Search Results - "Adler, I"

Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model by Guttenplan, Kevin A., Weigel, Maya K., Adler, Drew I., Couthouis, Julien, Liddelow, Shane A., Gitler, Aaron D., Barres, Ben A.

“…Reactive astrocytes have been implicated in the pathogenesis of neurodegenerative diseases, including a non-cell autonomous effect on motor neuron survival in…”
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Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury by Guttenplan, Kevin A., Stafford, Benjamin K., El-Danaf, Rana N., Adler, Drew I., Münch, Alexandra E., Weigel, Maya K., Huberman, Andrew D., Liddelow, Shane A.

“…Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells (RGCs) in the retina, often as a result of prolonged increases in…”
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Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes by Molitch, Mark E, Adler, Amanda I, Flyvbjerg, Allan, Nelson, Robert G, So, Wing-Yee, Wanner, Christoph, Kasiske, Bertram L, Wheeler, David C, de Zeeuw, Dick, Mogensen, Carl E

“…The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM)…”
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Seminal Fluid and Mate Choice: New Predictions by Crean, Angela J., Adler, Margo I., Bonduriansky, Russell

“…Recent evidence shows that seminal fluid can affect females and offspring independently of fertilisation in species lacking conventional ‘nuptial gifts’. We…”
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Evaluation of aneugenic effects of bisphenol A in somatic and germ cells of the mouse by Pacchierotti, F., Ranaldi, R., Eichenlaub-Ritter, U., Attia, S., Adler, I.-D.

“…Bisphenol A (BPA) is a synthetic monomer widely used to polymerize polycarbonate plastics and resins. It is shown in vitro to interfere with microtubules,…”
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Design of COVID-19 staged alert systems to ensure healthcare capacity with minimal closures by Yang, Haoxiang, Sürer, Özge, Duque, Daniel, Morton, David P., Singh, Bismark, Fox, Spencer J., Pasco, Remy, Pierce, Kelly, Rathouz, Paul, Valencia, Victoria, Du, Zhanwei, Pignone, Michael, Escott, Mark E., Adler, Stephen I., Johnston, S. Claiborne, Meyers, Lauren Ancel

“…Community mitigation strategies to combat COVID-19, ranging from healthy hygiene to shelter-in-place orders, exact substantial socioeconomic costs. Judicious…”
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Sexual conflict, life span, and aging by Adler, Margo I, Bonduriansky, Russell

“…The potential for sexual conflict to influence the evolution of life span and aging has been recognized for more than a decade, and recent work also suggests…”
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Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64) by Adler, Amanda I., Stevens, Richard J., Manley, Sue E., Bilous, Rudy W., Cull, Carole A., Holman, Rury R., UKPDS Group

“…Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64). The progression of nephropathy from…”
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Extrapolation beyond the end of trials to estimate long term survival and cost effectiveness by Latimer, Nicholas R, Adler, Amanda I

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Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes : a prospective observational study (UKPDS 75) by STRATTON, I. M, CULL, C. A, ADLER, A. I, MATTHEWS, D. R, NEIL, H. A. W, HOLMAN, R. R

“…The relative importance of glucose and blood pressure control in type 2 diabetes remains uncertain. We assessed interactive effects of glycaemia and systolic…”
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Gender effects on the incidence of aneuploidy in mammalian germ cells by Pacchierotti, F., Adler, I.-D., Eichenlaub-Ritter, U., Mailhes, J.B.

“…Aneuploidy occurs in 0.3% of newborns, 4% of stillbirths, and more than 35% of all human spontaneous abortions. Human gametogenesis is uniquely and…”
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Gamma-glutamyl transferase and risk of type II diabetes: an updated systematic review and dose-response meta-analysis by Kunutsor, Setor K., MD, PhD, Abbasi, Ali, MD, PhD, Adler, Amanda I., MD, PhD

“…Abstract Purpose We assessed the nature of the dose-response relationship between gamma-glutamyl transferase (GGT) levels and risk of incident type II diabetes…”
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Prevalence and projections of diabetes and pre-diabetes in adults in Sri Lanka-Sri Lanka Diabetes, Cardiovascular Study (SLDCS) by Katulanda, P., Constantine, G. R., Mahesh, J. G., Sheriff, R., Seneviratne, R. D. A., Wijeratne, S., Wijesuriya, M., McCarthy, M. I., Adler, A. I., Matthews, D. R.

“…Aims  To determine the prevalence of diabetes mellitus and pre‐diabetes (impaired fasting glucose and impaired glucose tolerance) in adults in Sri Lanka…”
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Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study by Stratton, Irene M, Adler, Amanda I, Neil, H Andrew W, Matthews, David R, Manley, Susan E, Cull, Carole A, Hadden, David, Turner, Robert C, Holman, Rury R

“…Abstract Objective: To determine the relation between exposure to glycaemia over time and the risk of macrovascular or microvascular complications in patients…”
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Diabetes as a Determinant of Mortality in Cystic Fibrosis by Chamnan, Parinya, Shine, Brian S.F, Haworth, Charles S, Bilton, Diana, Adler, Amanda I

“…OBJECTIVE: Diabetes is increasingly common in cystic fibrosis, but little information describing its influence on mortality exists. Using national U.K. data,…”
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Time-dependent event accumulation in a cardiovascular outcome trial of patients with type 2 diabetes and established atherosclerotic cardiovascular disease by Bethel, M Angelyn, Sourij, Harald, Stevens, Susanna R, Hannan, Karen, Lokhnygina, Yuliya, Adler, Amanda I, Peterson, Eric D, Holman, Rury R, Lopes, Renato D

“…Estimating cardiovascular (CV) event accrual is important for outcome trial planning. Limited data exist describing event accrual patterns in patients with…”
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Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study by Adler, Amanda I, Stratton, Irene M, Neil, H Andrew W, Yudkin, John S, Matthews, David R, Cull, Carole A, Wright, Alex D, Turner, Robert C, Holman, Rury R

“…Abstract Objective: To determine the relation between systolic blood pressure over time and the risk of macrovascular or microvascular complications in…”
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The role of national registries in improving patient safety for hip and knee replacements by Lübbeke, Anne, Silman, Alan J, Prieto-Alhambra, Daniel, Adler, Amanda I, Barea, Christophe, Carr, Andrew J

“…The serious adverse events associated with metal on metal hip replacements have highlighted the importance of improving methods for monitoring surgical…”
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Association of C-reactive protein with type 2 diabetes: prospective analysis and meta-analysis by Lee, C. C, Adler, A. I, Sandhu, M. S, Sharp, S. J, Forouhi, N. G, Erqou, S, Luben, R, Bingham, S, Khaw, K. T, Wareham, N. J

“…Aims/hypothesis We examined the association between serum C-reactive protein (CRP) and incident diabetes in a prospective study, and added these data to a…”
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Lower-extremity amputation in diabetes. The independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers by ADLER, A. I, BOYKO, E. J, AHRONI, J. H, SMITH, D. G

“…Lower-extremity amputation in diabetes. The independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers. A I Adler , E J Boyko , J…”
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