Search Results - "Adkins, L."
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Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis
Published in PLoS medicine (06-08-2019)“…Metformin is increasingly offered as an acceptable and economic alternative to insulin for treatment of gestational diabetes mellitus (GDM) in many countries…”
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2
Motor System Reorganization After Stroke: Stimulating and Training Toward Perfection
Published in Physiology (Bethesda, Md.) (01-09-2015)“…Stroke instigates regenerative responses that reorganize connectivity patterns among surviving neurons. The new connectivity patterns can be suboptimal for…”
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3
Comparative impact of pharmacological treatments for gestational diabetes on neonatal anthropometry independent of maternal glycaemic control: A systematic review and meta-analysis
Published in PLoS medicine (22-05-2020)“…Fetal growth in gestational diabetes mellitus (GDM) is directly linked to maternal glycaemic control; however, this relationship may be altered by oral…”
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4
Motor training induces experience-specific patterns of plasticity across motor cortex and spinal cord
Published in Journal of applied physiology (1985) (01-12-2006)“…1 Brain Rehabilitation Research Center, Malcom Randall Veterans Affairs Hospital, Gainesville; 2 Department of Neuroscience, Mcknight Brain Institute,…”
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The organization of the forelimb representation of the C57BL/6 mouse motor cortex as defined by intracortical microstimulation and cytoarchitecture
Published in Cerebral cortex (New York, N.Y. 1991) (01-04-2011)“…The organization of forelimb representation areas of the monkey, cat, and rat motor cortices has been studied in depth, but its characterization in the mouse…”
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6
Spending time: The impact of hours worked on work–family conflict
Published in Journal of vocational behavior (01-04-2012)“…Scholars have long assumed that as workers spend more time at work fewer hours are available for their non-work lives leading to negative effects in both…”
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7
Impact of metformin treatment during pregnancy on maternal outcomes: a systematic review/meta-analysis
Published in Scientific reports (29-04-2021)“…We systematically assessed the impact of metformin treatment on maternal pregnancy outcomes. PubMed, Ovid Embase, Medline, Web of Science, ClinicalTrials.gov…”
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8
Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet
Published in The FASEB journal (01-04-2016)“…Maternal diet during pregnancy influences the later life reproductive potential of female offspring. We investigate the molecular mechanisms underlying the…”
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9
Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets
Published in The FASEB journal (01-05-2009)“…Low birth weight (LBW) followed by accelerated postnatal growth is associated with increased risk of developing age-associated diseases such as type 2…”
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10
Maternal antioxidant treatment protects adult offspring against memory loss and hippocampal atrophy in a rodent model of developmental hypoxia
Published in The FASEB journal (01-05-2021)“…Chronic fetal hypoxia is one of the most common outcomes in complicated pregnancy in humans. Despite this, its effects on the long‐term health of the brain in…”
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Divergence of mechanistic pathways mediating cardiovascular aging and developmental programming of cardiovascular disease
Published in The FASEB journal (01-05-2016)“…Aging and developmental programming are both associated with oxidative stress and endothelial dysfunction, suggesting common mechanistic origins. However,…”
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12
Clinical and molecular evidence of accelerated ageing following very preterm birth
Published in Pediatric research (01-05-2020)“…Background The mechanisms responsible for the associations between very preterm birth and a higher risk of poor cardiovascular and metabolic health in adult…”
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13
Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair
Published in The Journal of biological chemistry (31-03-2017)“…Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity. When DSBs are repaired by homologous recombination, DNA ends can undergo…”
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14
Motor cortical stimulation promotes synaptic plasticity and behavioral improvements following sensorimotor cortex lesions
Published in Experimental neurology (01-07-2008)“…Cortical stimulation (CS) as a means to modulate regional activity and excitability in cortex is emerging as a promising approach for facilitating…”
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15
Suboptimal nutrition in utero causes DNA damage and accelerated aging of the female reproductive tract
Published in The FASEB journal (01-10-2013)“…Early life exposure to adverse environments can lead to a variety of metabolic and cardiovascular diseases in offspring. We hypothesize that female…”
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Chronic fetal hypoxia disrupts the peri‐conceptual environment in next‐generation adult female rats
Published in The Journal of physiology (01-05-2019)“…Key points Exposure to chronic hypoxia during gestation influences long‐term health and development, including reproductive capacity, across generations. If…”
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Poor maternal nutrition followed by accelerated postnatal growth leads to alterations in DNA damage and repair, oxidative and nitrosative stress, and oxidative defense capacity in rat heart
Published in The FASEB journal (01-01-2013)“…Low birth weight and accelerated postnatal growth lead to increased risk of cardiovascular disease. We reported previously that rats exposed to a low‐protein…”
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18
Blockade of SARS-CoV-2 spike protein-mediated cell–cell fusion using COVID-19 convalescent plasma
Published in Scientific reports (10-03-2021)“…The recent COVID-19 pandemic poses a serious threat to global public health, thus there is an urgent need to define the molecular mechanisms involved in…”
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Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats
Published in Disease models & mechanisms (01-10-2016)“…'Developmental programming', which occurs as a consequence of suboptimal in utero and early environments, can be associated with metabolic dysfunction in later…”
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20
Disrupted mitochondrial genes and inflammation following stroke
Published in Life sciences (1973) (01-12-2016)“…Determine the subacute time course of mitochondria disruption, cell death, and inflammation in a rat model of unilateral motor cortical ischemic stroke. Rats…”
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