Search Results - "Adkins, E. M"

Serotonin and Cocaine-sensitive Inactivation of Human Serotonin Transporters by Methanethiosulfonates Targeted to Transmembrane Domain I by Henry, L.Keith, Adkins, Erika M., Han, Qiao, Blakely, Randy D.

“…To explore aqueous accessibility and functional contributions of transmembrane domain (TM) 1 in human serotonin transporter (hSERT) proteins, we utilized the…”
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Rhodamine-Labeled 2β-Carbomethoxy-3β-(3,4-dichlorophenyl)tropane Analogues as High-Affinity Fluorescent Probes for the Dopamine Transporter by Cha, Joo Hwan, Zou, Mu-Fa, Adkins, Erika M, Rasmussen, Søren G. F, Loland, Claus Juul, Schoenenberger, Bernhard, Gether, Ulrik, Newman, Amy Hauck

“…Novel fluorescent ligands were synthesized to identify a high-affinity probe that would enable visualization of the dopamine transporter (DAT) in living cells…”
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Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition by Adkins, E M, Barker, E L, Blakely, R D

“…The serotonin (5-hydroxytryptamine, 5-HT) transporter (SERT) is responsible for the inactivation of synaptic 5-HT and is also a target for multiple…”
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High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol by Barker, E L, Perlman, M A, Adkins, E M, Houlihan, W J, Pristupa, Z B, Niznik, H B, Blakely, R D

“…Human and Drosophila melanogaster serotonin (5-HT) transporters (SERTs) exhibit similar 5-HT transport kinetics and can be distinguished pharmacologically by…”
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Sub-promille measurements and calculations of CO (3--0) overtone line intensities by Bielska, K, Kyuberis, A. A, Reed, Z. D, Li, Gang, Cygan, A, Ciuryło, R, Lisak, D, Adkins, E. M, Lodi, L, Hodges, J. T, Ebert, V, Zobov, N. F, Tennyson, J, Polyansky, O. L

“…Phys. Rev. Letts., 129, 043002 (2022) Intensities of lines in the near-infrared second overtone band (3--0) of $^{12}$C$^{16}$O are measured and calculated to…”
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The effects of advanced spectral line shapes on atmospheric carbon dioxide retrievals by Long, D.A., Adkins, E.M., Mendonca, J., Roche, S., Hodges, J.T.

“…•Advanced spectroscopic line shape models are required in the analysis of accurate laboratory and field observations of molecular spectra.•Incorporation of…”
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Membrane Mobility and Microdomain Association of the Dopamine Transporter Studied with Fluorescence Correlation Spectroscopy and Fluorescence Recovery after Photobleaching by Adkins, Erika M, Samuvel, Devadoss J, Fog, Jacob U, Eriksen, Jacob, Jayanthi, Lankupalle D, Vaegter, Christian Bjerggaard, Ramamoorthy, Sammanda, Gether, Ulrik

“…To investigate microdomain association of the dopamine transporter (DAT), we employed FCS (fluorescence correlation spectroscopy) and FRAP (fluorescence…”
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Targeting Cell Surface Receptors with Ligand-Conjugated Nanocrystals by Rosenthal, Sandra J, Tomlinson, Ian, Adkins, Erika M, Schroeter, Sally, Adams, Scott, Swafford, Laura, McBride, James, Wang, Yongqiang, DeFelice, Louis J, Blakely, Randy D

“…To explore the potential for use of ligand-conjugated nanocrystals to target cell surface receptors, ion channels, and transporters, we explored the ability of…”
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Tyr-95 and Ile-172 in Transmembrane Segments 1 and 3 of Human Serotonin Transporters Interact to Establish High Affinity Recognition of Antidepressants by Henry, L. Keith, Field, Julie R., Adkins, Erika M., Parnas, M. Laura, Vaughan, Roxanne A., Zou, Mu-Fa, Newman, Amy H., Blakely, Randy D.

“…In previous studies examining the structural determinants of antidepressant and substrate recognition by serotonin transporters (SERTs), we identified Tyr-95…”
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Oncology drugs for orphan indications: how are HTA processes evolving for this specific drug category? by Adkins, Elizabeth M, Nicholson, Lindsay, Floyd, David, Ratcliffe, Mark, Chevrou-Severac, Helene

“…Orphan drugs (ODs) are intended for the diagnosis, prevention, or treatment of rare diseases. Many cancer subtypes, including all childhood cancers, are…”
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Manipulating avocado fruit ripening with 1-methylcyclopropene by Adkins, Matthew F., Hofman, Peter J., Stubbings, Barbara A., Macnish, Andrew J.

“…Previous investigations with 1-methylcyclopropene (1-MCP) on avocado ( Persea americana Mill.) fruit have focussed mainly on improving storage life by reducing…”
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Recruitment of Tup1p and Cti6p regulates heme-deficient expression of Aft1p target genes by Crisp, R.J, Adkins, E.M, Kimmel, E, Kaplan, J

“…In the budding yeast Saccharomyces cerevisiae, transcription of genes encoding for the high‐affinity iron (FET3, FTR1) and copper (CTR1) transporters does not…”
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Using the National Weather Service's impact-based decision support services to prepare for extreme winter storms by Hosterman, Heather R, Lazo, Jeffrey K, Sprague-Hilderbrand, Jennifer M, Adkins, Jeffery E

“…In recent years, the National Weather Service (NWS) increased its focus on providing decision support services to the emergency management community and other…”
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Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy by Rasmussen, Søren G.F., Adkins, Erika M., Carroll, F.Ivy, Maresch, Martin J., Gether, Ulrik

“…Fluorescence spectroscopy techniques have proven extremely powerful for probing the molecular structure and function of membrane proteins. In this review, it…”
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