Search Results - "Adile, Ashley A"

An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma by Adile, Ashley A., Bakhshinyan, David, Suk, Yujin, Uehling, David, Saini, Mehakpreet, Aman, Ahmed, Magolan, Jakob, Subapanditha, Minomi K., McKenna, Dillon, Chokshi, Chirayu, Savage, Neil, Kameda-Smith, Michelle M., Venugopal, Chitra, Singh, Sheila K.

“…Purpose Medulloblastomas (MBs) constitute the most common malignant brain tumor in children and adolescents. MYC -amplified Group 3 MBs are characterized by…”
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Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma by Kameda-Smith, Michelle M., Zhu, Helen, Luo, En-Ching, Suk, Yujin, Xella, Agata, Yee, Brian, Chokshi, Chirayu, Xing, Sansi, Tan, Frederick, Fox, Raymond G., Adile, Ashley A., Bakhshinyan, David, Brown, Kevin, Gwynne, William D., Subapanditha, Minomi, Miletic, Petar, Picard, Daniel, Burns, Ian, Moffat, Jason, Paruch, Kamil, Fleming, Adam, Hope, Kristin, Provias, John P., Remke, Marc, Lu, Yu, Reya, Tannishtha, Venugopal, Chitra, Reimand, Jüri, Wechsler-Reya, Robert J., Yeo, Gene W., Singh, Sheila K.

“…Pediatric medulloblastoma (MB) is the most common solid malignant brain neoplasm, with Group 3 (G3) MB representing the most aggressive subgroup. MYC…”
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Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma by Kameda-Smith, Michelle M., Zhu, Helen, Luo, En-Ching, Suk, Yujin, Xella, Agata, Yee, Brian, Chokshi, Chirayu, Xing, Sansi, Tan, Frederick, Fox, Raymond G., Adile, Ashley A., Bakhshinyan, David, Brown, Kevin, Gwynne, William D., Subapanditha, Minomi, Miletic, Petar, Picard, Daniel, Burns, Ian, Moffat, Jason, Paruch, Kamil, Fleming, Adam, Hope, Kristin, Provias, John P., Remke, Marc, Lu, Yu, Reya, Tannishtha, Venugopal, Chitra, Reimand, Jüri, Wechsler-Reya, Robert J., Yeo, Gene W., Singh, Sheila K.

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Dynamic profiling of medulloblastoma surfaceome by Bakhshinyan, David, Suk, Yujin, Kuhlmann, Laura, Adile, Ashley A, Ignatchenko, Vladimir, Custers, Stefan, Gwynne, William D, Macklin, Andrew, Venugopal, Chitra, Kislinger, Thomas, Singh, Sheila K

“…Medulloblastoma (MB) is the most common type of malignant pediatric brain cancer. The current standard of care (SOC) involves maximal safe resection and…”
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Correction to: Dynamic profiling of medulloblastoma surfaceome by Bakhshinyan, David, Suk, Yujin, Kuhlmann, Laura, Adile, Ashley A, Ignatchenko, Vladimir, Custers, Stefan, Gwynne, William D, Macklin, Andrew, Venugopal, Chitra, Kislinger, Thomas, Singh, Sheila K

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WNT: an unexpected tumor suppressor in medulloblastoma by Manoranjan, Branavan, Adile, Ashley A., Venugopal, Chitra, Singh, Sheila K.

“…Medulloblastoma (MB) represents the most common malignant pediatric brain tumor and is defined by four molecular subgroups with WNT MB having the most…”
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Salvage therapy for progressive, treatment-refractory or recurrent pediatric medulloblastoma: a systematic review protocol by Adile, Ashley A, Kameda-Smith, Michelle M, Bakhshinyan, David, Banfield, Laura, Salim, Sabra K, Farrokhyar, Forough, Fleming, Adam J

“…Central nervous system tumors remain the leading cause of cancer-related mortality amongst children with solid tumors, with medulloblastoma (MB) representing…”
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Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma by Nawar, Nabanita, Bukhari, Shazreh, Adile, Ashley A, Suk, Yujin, Manaswiyoungkul, Pimyupa, Toutah, Krimo, Olaoye, Olasunkanmi O, Raouf, Yasir S, Sedighi, Abootaleb, Garcha, Harsimran Kaur, Hassan, Muhammad Murtaza, Gwynne, William, Israelian, Johan, Radu, Tudor B, Geletu, Mulu, Abdeldayem, Ayah, Gawel, Justyna M, Cabral, Aaron D, Venugopal, Chitra, de Araujo, Elvin D, Singh, Sheila K, Gunning, Patrick T

“…Histone deacetylase 6 (HDAC6) has been targeted in clinical studies for anticancer effects due to its role in oncogenic transformation and metastasis. Through…”
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Wnt activation as a therapeutic strategy in medulloblastoma by Manoranjan, Branavan, Venugopal, Chitra, Bakhshinyan, David, Adile, Ashley A., Richards, Laura, Kameda-Smith, Michelle M., Whitley, Owen, Dvorkin-Gheva, Anna, Subapanditha, Minomi, Savage, Neil, Tatari, Nazanin, McKenna, Dillon, Bassey-Archibong, Blessing, Winegarden, Neil, Hallett, Robin, Provias, John P., Yarascavitch, Blake, Ajani, Olufemi, Fleming, Adam, Bader, Gary D., Pugh, Trevor J., Doble, Bradley W., Singh, Sheila K.

“…Medulloblastoma (MB) is defined by four molecular subgroups (Wnt, Shh, Group 3, Group 4) with Wnt MB having the most favorable prognosis. Since prior reports…”
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Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer by Shouksmith, Andrew E, Shah, Fenil, Grimard, Michelle L, Gawel, Justyna M, Raouf, Yasir S, Geletu, Mulu, Berger-Becvar, Angelika, de Araujo, Elvin D, Luchman, H. Artee, Heaton, William L, Bakhshinyan, David, Adile, Ashley A, Venugopal, Chitra, O’Hare, Thomas, Deininger, Michael W, Singh, Sheila K, Konieczny, Stephen F, Weiss, Samuel, Fishel, Melissa L, Gunning, Patrick T

“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, incurable cancer with a 20% 1 year survival rate. While standard-of-care therapy can prolong life in…”
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Introduction to Cancer Stem Cells: Past, Present, and Future by Bakhshinyan, David, Adile, Ashley A, Qazi, Maleeha A, Singh, Mohini, Kameda-Smith, Michelle M, Yelle, Nick, Chokshi, Chirayu, Venugopal, Chitra, Singh, Sheila K

“…The Cancer Stem Cell (CSC) hypothesis postulates the existence of a small population of cancer cells with intrinsic properties allowing for resistance to…”
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Salvage Therapy for Childhood Medulloblastoma: A Single Center Experience by Kameda-Smith, Michelle M, Wang, Alick, Abdulhadi, Noora, Voth, Rebecca, Sergeant, Anjali, Maharaj, Arjuna, Bakhshinyan, David, Adile, Ashley A, Pai, Akshat M, Ajani, Olufemi, Yarascavitch, Blake, Alyman, M Cheryl, Duckworth, JoAnn, Samaan, M Constantine, Farrokhyar, Forough, Singh, Sheila K, Fleming, Adam

“…Children diagnosed with medulloblastoma (MB) who are refractory to upfront therapy or experience recurrence have very poor prognoses. Although phase I and…”
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Temporal profiling of therapy resistance in human medulloblastoma identifies novel targetable drivers of recurrence by Bakhshinyan, David, Adile, Ashley A, Liu, Jeff, Gwynne, William D, Suk, Yujin, Custers, Stefan, Burns, Ian, Singh, Mohini, McFarlane, Nicole, Subapanditha, Minomi K, Qazi, Maleeha A, Vora, Parvez, Kameda-Smith, Michelle M, Savage, Neil, Desmond, Kim L, Tatari, Nazanin, Tran, Damian, Seyfrid, Mathieu, Hope, Kristin, Bock, Nicholas A, Venugopal, Chitra, Bader, Gary D, Singh, Sheila K

“…Medulloblastoma (MB) remains a leading cause of cancer-related mortality among children. The paucity of MB samples collected at relapse has hindered the…”
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EMBR-22. RATIONAL DEVELOPMENT OF SYNERGISTIC THERAPIES ALONGSIDE BMI1 INHIBITION FOR GROUP 3 MEDULLOBLASTOMA by Bakhshinyan, David, Adile, Ashley A, Venugopal, Chitra, Brown, Kevin, Chan, Katherine, Qazi, Maleeha A, Chokshi, Chirayu, Gwynne, William D, Tieu, David, Moffat, Jason, Singh, Sheila

“…Medulloblastoma (MB) is the most common pediatric brain tumor. Of its four distinct molecular subgroups, Group 3 MBs are associated with increased risk of…”
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BMI1 is a therapeutic target in recurrent medulloblastoma by Bakhshinyan, David, Venugopal, Chitra, Adile, Ashley A., Garg, Neha, Manoranjan, Branavan, Hallett, Robin, Wang, Xin, Mahendram, Sujeivan, Vora, Parvez, Vijayakumar, Thusyanth, Subapanditha, Minomi, Singh, Mohini, Kameda-Smith, Michelle Masayo, Qazi, Maleeha, McFarlane, Nicole, Mann, Aneet, Ajani, Olufemi A., Yarascavitch, Blake, Ramaswamy, Vijay, Farooq, Hamza, Morrissy, Sorana, Cao, Liangxian, Sydorenko, Nadiya, Baiazitov, Ramil, Du, Wu, Sheedy, Josephine, Weetall, Marla, Moon, Young-Choon, Lee, Chang-Sun, Kwiecien, Jacek M., Delaney, Kathleen H., Doble, Brad, Cho, Yoon-Jae, Mitra, Siddhartha, Kaplan, David, Taylor, Michael D., Davis, Thomas W., Singh, Sheila K.

“…Medulloblastoma (MB) is the most frequent malignant pediatric brain tumor, representing 20% of newly diagnosed childhood central nervous system malignancies…”
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