Search Results - "Adighibe, Omanma"

Vessel co‐option in primary human tumors and metastases: an obstacle to effective anti‐angiogenic treatment? by Donnem, Tom, Hu, Jiangting, Ferguson, Mary, Adighibe, Omanma, Snell, Cameron, Harris, Adrian L., Gatter, Kevin C., Pezzella, Francesco

“…Angiogenesis has been regarded as essential for tumor growth and progression. Studies of many human tumors, however, suggest that their microcirculation may be…”
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Why some tumours trigger neovascularisation and others don't: the story thus far by Adighibe, Omanma, Leek, Russell D, Fernandez-Mercado, Marta, Hu, Jiangting, Snell, Cameron, Gatter, Kevin C, Harris, Adrian L, Pezzella, Francesco

“…Angiogenesis is not essential for tumours to develop and expand, as cancer can also grow in a non-angiogenic fashion, but why this type of growth occurs is…”
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The Role of JMY in p53 Regulation by Adighibe, Omanma, Pezzella, Francesco

“…Following the event of DNA damage, the level of tumour suppressor protein p53 increases inducing either cell cycle arrest or apoptosis. Junctional Mediating…”
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Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs by Blom, Elin S, Giedraitis, Vilmantas, Arepalli, Sampath, Hamshere, Marian L, Adighibe, Omanma, Goate, Alison, Williams, Julie, Lannfelt, Lars, Hardy, John, Vrièze, Fabienne Wavrant-De, Glaser, Anna

“…Genome-wide linkage studies for Alzheimer's disease have implicated several chromosomal regions as potential loci for susceptibility genes. In the present…”
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JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues by Adighibe, Omanma, Turley, Helen, Leek, Russell, Harris, Adrian, Coutts, Amanda S, La Thangue, Nick, Gatter, Kevin, Pezzella, Francesco

“…JMY is a p300-binding protein with dual action: by enhancing P53 transcription in the nucleus, it plays an important role in the cellular response to DNA…”
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Genetic variability at the LXR gene ( NR1H2) may contribute to the risk of Alzheimer's disease by Adighibe, Omanma, Arepalli, Sampath, Duckworth, Jaime, Hardy, John, Wavrant-De Vrièze, Fabienne

“…We have initiated a systematic analysis of the role of cholesterol metabolizing genes as risk factors for Alzheimer's disease pathogenesis. As part of this…”
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Loss of chaperone protein in human cancer by Adighibe, Omanma

“…TRAP1 is a Heat Shock Protein (HSP) chaperone to retinoblastoma but also associated to the tumor necrosis factor receptor. HSPs are primarily up regulated in…”
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ABCA1 polymorphisms and Alzheimer's disease by Wavrant-De Vrièze, Fabienne, Compton, Danielle, Womick, Meridith, Arepalli, Sampath, Adighibe, Omanma, Li, Ling, Pérez-Tur, Jordi, Hardy, John

“…In our search for genetic factors related to the development of Alzheimer's disease, we have genotyped 332 pedigrees for three coding polymorphisms in the…”
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P4-141 The liver X receptor: candidate gene for Alzheimer's disease by Adighibe, Omanma, Arepalli, Sampath, Hardy, John, Wavrant-De Vrieze, Fabienne

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Chromosome 21 BACE2 haplotype associates with Alzheimer's disease: A two-stage study by Myllykangas, Liisa, Wavrant-De Vrièze, Fabienne, Polvikoski, Tuomo, Notkola, Irma-Leena, Sulkava, Raimo, Niinistö, Leena, Edland, Steven D., Arepalli, Sampath, Adighibe, Omanma, Compton, Danielle, Hardy, John, Haltia, Matti, Tienari, Pentti J.

“…Genetic linkage studies have provided evidence for a late-onset Alzheimer's disease (AD) susceptibility locus on chromosome 21q. We have tested, in a two-stage…”
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Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? by Blom, Elin S., Holmans, Peter, Arepalli, Sampath, Adighibe, Omanma, Hamshere, Marian L., Gatz, Margaret, Pedersen, Nancy L., Bergem, A. L. Mina, Owen, Michael J., Hollingworth, Paul, Goate, Alison, Williams, Julie, Lannfelt, Lars, Hardy, John, Wavrant-De Vrièze, Fabienne, Glaser, Anna

“…We have studied the impact of the apolipoprotein E gene (APOE) on the chromosome 19 linkage peak from an analysis of sib‐pairs affected by Alzheimer's disease…”
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P4-070 Is APOE exclusively responsible for the AD linkage peak on chromosome 19? by Blom, Elin, Holmans, Peter, Arepalli, Sampath, Adighibe, Omanma, Hardy, John, Lannfelt, Lars, Glaser, Anna, Wavrant-De Vrièze, Fabienne

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Why some tumours trigger neovascularisation andothers don’t：the story thus far by Omanma Adighibe, Russell DLeek, Marta FernandezMercado, JiangtingHu, Cameron Snell, Kevin CGatter, AdrianLHarris, Francesco Pezzella

“…Background:Angiogenesis is not essential for tumours to develop and expand, as cancer can also grow in a non?angiogenic fashion, but why this type of growth…”
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