Search Results - "Adib, Mehdi"
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Design, synthesis, in vitro α-glucosidase inhibition, docking, and molecular dynamics of new phthalimide-benzenesulfonamide hybrids for targeting type 2 diabetes
Published in Scientific reports (22-06-2022)“…In the present work, a new series of 14 novel phthalimide-benzenesulfonamide derivatives 4a – n were synthesized, and their inhibitory activity against yeast…”
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2
A solvent-free reaction between acetophenone oximes and epoxy styrenes: an efficient synthesis of 2,4,6-triarylpyridines under neutral conditions
Published in Tetrahedron letters (16-07-2014)“…An efficient synthesis of 2,4,6-triarylpyridines is described which involves heating a mixture of an acetophenone oxime and an epoxy styrene under neutral,…”
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3
An efficient and targeted synthetic approach towards new highly substituted 6-amino-pyrazolo[1,5-a]pyrimidines with α-glucosidase inhibitory activity
Published in Scientific reports (13-02-2020)“…In an attempt to find novel α -glucosidase inhibitors, an efficient, straightforward reaction to synthesize a library of fully substituted…”
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4
Palladium supported magnetic Fucus Vesiculosus extract as a natural and novel catalyst for the synthesis of N-alkyl-2-(4-methyl-1-oxoisoquinolin-2(1H)-yl)-2-phenylacetamide derivatives
Published in Scientific reports (23-01-2023)“…In this paper, a novel catalyst is introduced based on the immobilization of palladium onto magnetic Fucus Vesiculosus extract (Pd@m FuVe catalyst). For the…”
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5
Catalyst-free three-component reaction between 2-aminopyridines (or 2-aminothiazoles), aldehydes, and isocyanides in water
Published in Tetrahedron letters (08-10-2007)“…A catalyst-free and convenient protocol is described for the preparation of 3-aminoimidazo[1,2- a]pyridines and 5-aminoimidazo[2,1- b][1,3]thiazoles via…”
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Design and synthesis of new imidazo[1,2-b]pyrazole derivatives, in vitro α-glucosidase inhibition, kinetic and docking studies
Published in Molecular diversity (01-02-2020)“…A new series of imidazo[1,2-b]pyrazole derivatives 4a–o was designed, synthesized, and screened for in vitro α-glucosidase inhibitory activity. All compounds…”
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7
A one-pot, three-component and solvent-free synthesis of 2,3-disubstituted isoindolin-1-ones
Published in Tetrahedron letters (12-08-2015)“…[Display omitted] A one-pot and three-component reaction is described for the preparation of 2,3-disubstituted isoindolin-1-ones. Heating a mixture of…”
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8
New acridine-9-carboxamide linked to 1,2,3-triazole-N-phenylacetamide derivatives as potent α-glucosidase inhibitors: design, synthesis, in vitro, and in silico biological evaluations
Published in Medicinal chemistry research (01-10-2020)“…α-Glucosidase plays a major role in degradation of carbohydrates to glucose. Therefore, inhibition of this enzyme can be useful in the treatment of…”
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9
One-Pot Four-Component Synthesis of Thieno[2,3-d]pyrimidin-4-amines via Sequential Gewald/Cyclocondensation Reactions
Published in Helvetica chimica acta (01-08-2015)“…A one‐pot four‐component synthesis of thieno[2,3‐d]pyrimidin‐4‐amines via sequential Gewald/cyclocondensation reactions is described…”
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10
Efficient highly diastereoselective synthesis of 1,8a-dihydro-7H-imidazo[2,1-b][1,3]oxazines
Published in Tetrahedron (03-04-2006)Get full text
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11
An efficient synthesis of 3-amino-2-arylimidazo[1,2- a]pyridines
Published in Tetrahedron letters (18-08-2008)“…An efficient synthesis of 3-amino-2-arylimidazo[1,2- a]pyridines is described via a novel multicomponent reaction between 2-aminopyridines, benzaldehydes and…”
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12
Reaction between isocyanides and chalcones: an efficient solvent-free synthesis of 5-hydroxy-3,5-diaryl-1,5-dihydro-2H-pyrrol-2-ones
Published in Tetrahedron letters (01-11-2007)Get full text
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13
A new, one-pot, three-component synthesis of 4H-pyrido[1,2-a]pyrimidines, 4H-pyrimido[1,2-a]pyrimidines, and 4H-pyrazino[1,2-a]pyrimidines
Published in Tetrahedron (01-11-2007)“…A new, one-pot and three-component synthesis of 4H-pyrido[1,2- a]pyrimidines, 4H-pyrimido[1,2-a]pyrimidines, and 4H- pyrazino[1,2-a]pyrimidines is described…”
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14
Convenient Synthesis of 2-Aminothiophene Derivatives by Acceleration of Gewald Reaction Under Ultrasonic Aqueous Conditions
Published in Synthetic communications (25-06-2010)“…Under ultrasound irradiation and in the presence of H 2 O/Et 2 NH, ethyl cyanoacetate or malononitrile can combine with α -methylene carbonyl compounds and…”
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15
1-Methylimidazole-catalyzed reaction between tosylmethyl isocyanide and dialkyl acetylenedicarboxylates:An efficient synthesis of functionalized pyrroles
Published in Chinese chemical letters (01-03-2011)“…An efficient 1-methylimidazole-catalyzed synthesis of dialkyl 2-[(4-methylphenyl)sulfonyl]-1H-pyrrole-3,4-dicarboxylates is described.The reactive 1:1…”
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16
Reaction between Guanidine Hydrochloride and Chalcones: An Efficient Solvent-free Synthesis of 2,4,6-Triarylpyridines under Microwave Irradiation
Published in Chemistry letters (05-10-2008)“…A series of 2,4,6-triarylpyridines have been synthesized via an efficient solvent-free reaction between guanidine hydrochloride and chalcones under microwave…”
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An efficient synthesis of fully substituted pyrazolo[3,4-b]pyridin-5-amines from α-azidochalcones
Published in Tetrahedron (17-05-2018)“…A facile, mild and efficient procedure for the synthesis of fully substituted pyrazolo[3,4-b]pyridin-5-amines is reported. A mixture of an α-azidochalcone, a…”
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18
A synthesis of pyrazino[1,2-a]indoles via one-pot cascade Ugi condensation and N-annulation under mild conditions
Published in Tetrahedron letters (21-12-2021)“…[Display omitted] A novel, one-pot, mild and operationally simple synthetic approach for the synthesis of pyrazino[1,2-a]indole derivatives is reported. The…”
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19
One-pot synthesis of imidazo[1,2- a]pyridines from benzyl halides or benzyl tosylates, 2-aminopyridines and isocyanides
Published in Tetrahedron letters (22-06-2011)“…A one-pot synthesis of imidazo[1,2- a]pyridines is described. Benzyl halides or benzyl tosylates are oxidized to aldehydes under mild Kornblum conditions which…”
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20
CuI catalyzed-novel one-pot synthesis of aryl alkenyl thioethers through Ullmann-type coupling reactions using carbon disulfide as a sulfur surrogate in the presence of nitroalkanes and aryl iodides
Published in Tetrahedron letters (16-05-2018)“…[Display omitted] •Some novel aryl alkenyl thioethers through Ullmann-type coupling were fabricated.•The products obtained in high yields.•The S-arylation of…”
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