Search Results - "Adhikari, Bandita"
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Computational Modeling of Macrophage Iron Sequestration during Host Defense against Aspergillus
Published in mSphere (31-08-2022)“…Iron is essential to the virulence of Aspergillus species, and restricting iron availability is a critical mechanism of antimicrobial host defense. Macrophages…”
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A feasibility study on yoga's mechanism of action for chronic low back pain: psychological and neurophysiological changes, including global gene expression and DNA methylation, following a yoga intervention for chronic low back pain
Published in Pilot and feasibility studies (07-07-2022)“…Yoga has been shown to reduce pain and improve function in populations with chronic low back pain (cLBP), yet the underlying molecular mechanisms remain…”
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Understanding Fungal Infection and Chronic Pain from a Systems Biology Perspective
Published 01-01-2021“…Systems biology is an interdisciplinary field that integrates key biological elements such as DNA, RNA, protein, cell, organ etc. into a computational or a…”
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Dissertation -
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Short Telomeres Associate with Hyperphosphorylated Tau Burden in Primary Age‐Related Tauopathy
Published in Alzheimer's & dementia (01-12-2022)“…Background Primary age‐related tauopathy (PART) is characterized by neuropathological hyperphosphorylated tau burden (p‐tau) in the absence of significant…”
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Journal Article -
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Multi-scale mechanistic modelling of the host defence in invasive aspergillosis reveals leucocyte activation and iron acquisition as drivers of infection outcome
Published in Journal of the Royal Society interface (01-04-2022)“…Aspergillus species are ubiquitous environmental moulds, with spores inhaled daily by most humans. Immunocompromised hosts can develop an invasive infection…”
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SHORT TELOMERES ASSOCIATE WITH HYPERPHOSPHORYLATED TAU BURDEN IN PRIMARY AGE-RELATED TAUOPATHY
Published in Innovation in aging (20-12-2022)“…Abstract Aging is a major risk factor for hyperphosphorylated tau burden (p-tau). Telomeres lengths (TL) shorten with age and various sources of DNA damage,…”
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Abstract 1956: miR-181d degradation mediated genetic heterogeneity and acquired resistance
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract When unrepaired, alkylated DNA can induce cell death or trigger mutagenesis. Cellular capacity for repair of these lesions by O6-methylguanine…”
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The use of TMZ embedded hydrogels for the treatment of orthotopic human glioma xenografts
Published in Journal of clinical neuroscience (01-11-2017)“…•Therapeutic effect of systemic temozolomide is limited by the blood brain barrier.•Temozolomide can be loaded onto a novel hydrogel matrix.•Hydrogels locally…”
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EPIG-03EPIGENETIC SUPPRESSION OF EGFR SIGNALING IN G-CIMP + GLIOBLASTOMAS
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2015)Get full text
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Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas
Published in Oncotarget (15-09-2014)“…The intrinsic signaling cascades and cell states associated with the Glioma CpG Island Methylator Phenotype (G-CIMP) remain poorly understood. Using published…”
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Journal Article