Search Results - "Adeyemi, Samson A"

In Vitro Prototyping of a Nano-Organogel for Thermo-Sonic Intra-Cervical Delivery of 5-Fluorouracil-Loaded Solid Lipid Nanoparticles for Cervical Cancer by Adeyemi, Samson A., Az-Zamakhshariy, Zardad, Choonara, Yahya E.

“…Solid lipid nanoparticles (SLNs) are used extensively to achieve site-specific drug delivery with improved bioavailability and reduced toxicity. This work…”
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In Vitro and In Vivo Evaluation of a Cyclic LyP-1-Modified Nanosystem for Targeted Endostatin Delivery in a KYSE-30 Cell Xenograft Athymic Nude Mice Model by Adeyemi, Samson A, Choonara, Yahya E

“…This work investigated the use of LyP-1 as a homing peptide for p32 receptor targeting on the surface of an endostatin (ENT)-loaded chitosan-grafted nanosystem…”
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Cell Secretome Strategies for Controlled Drug Delivery and Wound-Healing Applications by Ibrahim, Ranya, Mndlovu, Hillary, Kumar, Pradeep, Adeyemi, Samson A., Choonara, Yahya E.

“…There is significant interest in using stem cells in the management of cutaneous wounds. However, potential safety, efficacy, and cost problems associated with…”
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Cellulose nanocrystals from Siam weed: Synthesis and physicochemical characterization by Ogunjobi, Joseph K., Adewale, Adetola I., Adeyemi, Samson A.

“…The use of biomass for the development of environmentally friendly and industrially useful materials is still attracting global interest. Herein, cellulose…”
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Synthesis and Cytotoxic Activity of 1,2,4-Triazolo-Linked Bis-Indolyl Conjugates as Dual Inhibitors of Tankyrase and PI3K by Yakkala, Prasanna A., Panda, Samir R., Shafi, Syed, Naidu, V. G. M., Yar, M. Shahar, Ubanako, Philemon N., Adeyemi, Samson A., Kumar, Pradeep, Choonara, Yahya E., Radchenko, Eugene V., Palyulin, Vladimir A., Kamal, Ahmed

“…A series of new 1,2,4-triazolo-linked bis-indolyl conjugates (15a–r) were prepared by multistep synthesis and evaluated for their cytotoxic activity against…”
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Dual Rifampicin and Isoniazid Mannose-Decorated Lipopolysaccharide Nanospheres for Macrophage- Targeted Lung Delivery by Sumaila, Mumuni, Kumar, Pradeep, Ubanako, Philemon, Adeyemi, Samson A, Choonara, Yahya E

“…Currently, the treatment protocols for tuberculosis (TB) have several challenges, such as inconsistent oral bioavailability, dose-related adverse effects, and…”
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Synthesis of Novel Conjugated Linoleic Acid (CLA)-Coated Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for the Delivery of Paclitaxel with Enhanced In Vitro Anti-Proliferative Activity on A549 Lung Cancer Cells by Ngema, Lindokuhle M, Adeyemi, Samson A, Marimuthu, Thashree, Ubanako, Philemon, Wamwangi, Daniel, Choonara, Yahya E

“…The application of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) as a nanomedicine for Non-Small Cell Lung Carcinoma (NSCLC) can provide effective…”
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Folate-decorated, endostatin-loaded, nanoparticles for anti-proliferative chemotherapy in esophaegeal squamous cell carcinoma by Adeyemi, Samson A., Choonara, Yahya E., Kumar, Pradeep, du Toit, Lisa C., Marimuthu, Thashree, Kondiah, Pierre P.D., Pillay, Viness

“…[Display omitted] •Folate decorated nanocarriers are synthesized for squamous cell carcinoma.•Enhanced uptake and intra-cellular trafficking of functionalized…”
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A Closed Loop Stimuli-Responsive Concanavalin A-Loaded Chitosan–Pluronic Hydrogel for Glucose-Responsive Delivery of Short-Acting Insulin Prototyped in RIN-5F Pancreatic Cells by Mansoor, Shazia, Adeyemi, Samson A, Kondiah, Pierre P. D, Choonara, Yahya E

“…The optimal treatment of diabetes (in particular, type 1 diabetes—T1D) remains a challenge. Closed-loop systems (implants/inserts) provide significant…”
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Capparis sepiaria -Loaded Sodium Alginate Single- and Double-Layer Membrane Composites for Wound Healing by Ndlovu, Sindi P, Motaung, Keolebogile S C M, Razwinani, Mapula, Alven, Sibusiso, Adeyemi, Samson A, Ubanako, Philemon N, Ngema, Lindokuhle M, Fonkui, Thierry Y, Ndinteh, Derek T, Kumar, Pradeep, Choonara, Yahya E, Aderibigbe, Blessing A

“…: Effective wound dressing is the key solution to combating the increased death rate and prolonged hospital stay common to patients with wounds. : Sodium…”
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Short Antiangiogenic MMP‑2 Peptide-Decorated Conjugated Linoleic Acid-Coated SPIONs for Targeted Paclitaxel Delivery in an A549 Cell Xenograft Mouse Tumor Model by Ngema, Lindokuhle M., Adeyemi, Samson A., Marimuthu, Thashree, Ubanako, Philemon N., Ngwa, Wilfred, Choonara, Yahya E.

“…The design of targeted antiangiogenic nanovectors for the delivery of anticancer drugs presents a viable approach for effective management of nonsmall-cell…”
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A review on engineered magnetic nanoparticles in Non-Small-Cell lung carcinoma targeted therapy by Ngema, Lindokuhle M., Adeyemi, Samson A., Marimuthu, Thashree, Choonara, Yahya E.

“…[Display omitted] •Magnetic nanoparticles offer high drug-loading capacity and tumor penetration.•Homing peptides facilitate specific targeting of angiogenesis…”
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Synthesis and in vitro assessment of gold nanoparticles conjugated with extracts, sterols and pure compounds derived from marine sponges from the Indian and Pacific Oceans by Ramanjooloo, Avin, Bekah, Devesh, Adeyemi, Samson A., Ubanako, Philemon, Ngema, Lindokuhle, Choonara, Yahya E., Williams, David E., Polishchuk, Elena A., Andersen, Raymond J., Bhaw-Luximon, Archana

“…Gold nanoparticles (AuNPs) exhibit different physical properties compared to small molecules, bulk materials and other nanoparticles. Their synthesis using…”
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Novel ferrocenylbisphosphonate hybrid compounds: Synthesis, characterization and potent activity against cancer cell lines by Anusionwu, Chioma G., Aderibigbe, Blessing A., Adeyemi, Samson A., Ubanako, Philemon, Oselusi, Samson O., Choonara, Yahya E., Yangkou Mbianda, Xavier

“…[Display omitted] The toxicity of existing anticancer agents on healthy cells and the emergence of multidrug-resistance cancer cells have led to the search for…”
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Sodium alginate-based nanofibers loaded with Capparis Sepiaria plant extract for wound healing by Ndlovu, Sindi P., Motaung, Keolebogile S. C. M, Adeyemi, Samson A., Ubanako, Philemon, Ngema, Lindokuhle, Fonkui, Thierry Y., Ndinteh, Derek T., Kumar, Pradeep, Choonara, Yahya E., Aderibigbe, Blessing A.

“…Burn wounds are associated with infections, drug resistance, allergic reactions, odour, bleeding, excess exudates, and scars, requiring prolonged hospital…”
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Carboxymethyl cellulose/poloxamer gels enriched with essential oil and Ag nanoparticles: promising wound dressings by Alven, Sibusiso, Ubanako, Philemon, Adeyemi, Samson A, Ndinteh, Derek T, Choonara, Yahya E, Aderibigbe, Blessing Atim

“…Essential oils are promising antibacterial and wound-healing agents that should be explored for the design of wound dressings. Topical gels prepared from a…”
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Recent patents on water-soluble polysaccharides for advanced drug delivery, tissue engineering and regenerative medicine by Adeyemi, Samson A, Choonara, Yahya E

“…Water-soluble polysaccharides have unique properties and have found wide application in the design of advanced drug-delivery systems and the biofabrication of…”
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Surface Immobilization of Anti-VEGF Peptide on SPIONs for Antiangiogenic and Targeted Delivery of Paclitaxel in Non-Small-Cell Lung Carcinoma by Ngema, Lindokuhle M., Adeyemi, Samson A., Marimuthu, Thashree, Ubanako, Philemon N., Ngwa, Wilfred, Choonara, Yahya E.

“…A design has been established for the surface decoration of superparamagnetic iron oxide nanoparticles (SPIONs) with anti-vascular endothelial growth factor…”
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A Topical Alginate-Based Wound Gel Fixated with Metal-Based Nanoparticles and Tranexamic Acid as a Hemostatic Wound Healing System by Nqoro, Xhamla, Adeyemi, Samson A., Ubanako, Philemon, Ndinteh, Derek T., Kumar, Pradeep, Choonara, Yahya E., Aderibigbe, Blessing A.

“…Wounds are usually accompanied by complications such as excessive bleeding and bacteria invasion. The design of wound dressings that rapidly stop excessive…”
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Dopamine-Loaded Polymer-Drug Conjugates for Potential Synergistic Anti-Cancer Treatment by Tobeka Naki, Matshe, W, Ubanako, Philemon, Adeyemi, Samson A, Balogun, MO, S Sinha Ray, Choonara, Yahya E, Blessing Atim Aderibigbe

“…The combination of dopamine with anticancer drugs can result in enhanced anticancer activity. Polymer-drug conjugates (PDCs) containing anticancer drugs, such…”
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