Search Results - "Adermann, K."

Human β‐defensin 4: a novel inducible peptide with a specific salt‐sensitive spectrum of antimicrobial activity by García, José-Ramón Conejo, Krause, Alexander, Schulz, Sandra, Rodríguez-Jiménez, Francisco-Javier, Klüver, Enno, Adermann, Knut, Forssmann, Ulf, Frimpong-Boateng, Adjoa, Bals, Robert, Forssmann, Wolf-Georg

“…ABSTRACT β‐Defensins are antibiotic peptides involved in host defense at the epithelial surface. Three human β‐defensins (hBDs)‐‐hBD‐1, hBD‐2, and hBD‐3‐‐have…”
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Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily by ADERMANN, KNUT, WATTLER, FRANK, WATTLER, SIGRID, HEINE, GABRIELE, MEYER, MARKUS, FORSSMANN, WOLF-GEORG, NEHLS, MICHAEL

“…Members of the Ly-6/uPAR protein family share one or several repeat units of the Ly-6/uPAR domain that is defined by a distinct disulfide bonding pattern…”
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Dual function of the propeptide of prouroguanylin in the folding of the mature peptide: disulfide-coupled folding and dimerization by Hidaka, Y, Shimono, C, Ohno, M, Okumura, N, Adermann, K, Forssmann, W G, Shimonishi, Y

“…Guanylyl cyclase activating peptide II (GCAP-II), an endogenous ligand of guanylyl cyclase C, is produced via the processing of the precursor protein…”
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HCC-1, a novel chemokine from human plasma by Schulz-Knappe, P, Mägert, H J, Dewald, B, Meyer, M, Cetin, Y, Kubbies, M, Tomeczkowski, J, Kirchhoff, K, Raida, M, Adermann, K, Kist, A, Reinecke, M, Sillard, R, Pardigol, A, Uguccioni, M, Baggiolini, M, Forssmann, W G

“…A novel CC chemokine, HCC-1, was isolated from the hemofiltrate of patients with chronic renal failure. HCC-1 has a relative molecular mass of 8,673 and…”
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Segmental differences in the effects of guanylin and Escherichia coli heat-stable enterotoxin on Cl- secretion in human gut by Kuhn, M, Adermann, K, Jähne, J, Forssmann, W G, Rechkemmer, G

“…1. Mucosally added synthetic guanylin and Escherichia coli heat-stable enterotoxin (STa) increased short-circuit current (ISC) across isolated muscle-stripped…”
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Enterochromaffin Cells of the Digestive System: Cellular Source of Guanylin, a Guanylate Cyclase-Activating Peptide by CETIN, Y, KUHN, M, KULAKSIZ, H, ADERMANN, K, BARGSTEN, G, GRUBE, D, FORSMANN, W.-G

“…Guanylin, a bioactive peptide, has recently been isolated from the intestine; this peptide activates intestinal guanylate cyclase (i.e., guanylate cyclase C)…”
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The 15-domain serine proteinase inhibitor LEKTI: biochemical properties, genomic organization, and pathophysiological role by Mägert, Hans-Jürgen, Kreutzmann, P, Drögemüller, K, Ständker, L, Adermann, K, Walden, M, John, H, Korting, H C, Forssmann, W G

“…Proteinases are involved in specific and non-specific proteolytic reactions, and participate in many pathophysiological processes. Normally, they are regulated…”
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Immunocytochemical localization of human 5 alpha-reductase 2 with polyclonal antibodies in androgen target and non-target human tissues by Eicheler, W, Tuohimaa, P, Vilja, P, Adermann, K, Forssmann, WG, Aumuller, G

“…We studied the tissue distribution and cellular localization of 5 alpha-reductase 2, the human prostatic isoenzyme, in different human tissues, both…”
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Role of the prosequence of guanylin by SCHULZ, AXEL, MARX, UTE C., HIDAKA, YUJI, SHIMONISHI, YASUTSUGU, RÖSCH, PAUL, FORSSMANN, WOLF-GEORG, ADERMANN, KNUT

“…Guanylin is a guanylyl cyclase (GC)-activating peptide that is mainly secreted as the corresponding prohormone of 94 amino acid residues. In this study, we…”
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Monoclonal antibodies against boar sperm zona pellucida-binding protein AWN-1. Characterization of a continuous antigenic determinant and immunolocalization of AWN epitopes in inseminated sows by Calvete, J.J, Ensslin, M, Mburu, J, Iborra, A, Martinez, P, Adermann, K, Waberski, D, Sanz, K, Sanz, L, Topfer-Petersen, E, Weitze, K.F

“…Boar spermadhesin AWN-1 is a sperm surface-associated 14.7-kDa lectin and a major protein of porcine seminal plasma. AWN-1 binds to beta-galactosides and to…”
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Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection by Münch, Jan, Rücker, Elke, Ständker, Ludger, Adermann, Knut, Goffinet, Christine, Schindler, Michael, Wildum, Steffen, Chinnadurai, Raghavan, Rajan, Devi, Specht, Anke, Giménez-Gallego, Guillermo, Sánchez, Pedro Cuevas, Fowler, Douglas M., Koulov, Atanas, Kelly, Jeffery W., Mothes, Walther, Grivel, Jean-Charles, Margolis, Leonid, Keppler, Oliver T., Forssmann, Wolf-Georg, Kirchhoff, Frank

“…Sexual intercourse is the major route of HIV transmission. To identify endogenous factors that affect the efficiency of sexual viral transmission, we screened…”
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Functional analysis of chemically synthesized derivatives of the human CC chemokine CCL15/HCC-2, a high affinity CCR1 ligand by Escher, S.E., Vakili, J., Forssmann, U., Frimpong-Boateng, A., Sticht, H., Detheux, M., Adermann, K.

“…:  The CCL15 is a human CC chemokine that activates the receptors, CCR1 and CCR3. Unlike other chemokines, it contains an unusually long N‐terminal domain of…”
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Analysis of the Human Guanylin Gene and the Processing and Cellular Localization of the Peptide by Hill, Oliver, Kuhn, Michaela, Zucht, Hans-Dieter, Cetin, Yalcin, Kulaksiz, Hasan, Adermann, Knut, Klock, Gerd, Rechkemmer, Gerhard, Forssmann, Wolf-Georg, Magert, Hans-Jurgen

“…The complete cell biological analysis of human guanylin, a recently discovered regulatory peptide, is offered in this investigation: (i) the nucleotide…”
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Human natriuretic peptides exhibit antimicrobial activity by Krause, A, Liepke, C, Meyer, M, Adermann, K, Forssmann, W G, Maronde, E

“…Here we describe a novel function for members of the well-characterized human natriuretic peptide family. Human "brain-type natriuretic peptide" (hBNP-32) as…”
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Chemical synthesis of β-defensins and LEAP-1/hepcidin by Klüver, E., Schulz, A., Forssmann, W.-G., Adermann, K.

“…: A large and steadily growing subfamily of antimicrobially active peptides of animals and plants is formed by the defensins, which are highly…”
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Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide by Münch, Jan, Ständker, Ludger, Adermann, Knut, Schulz, Axel, Schindler, Michael, Chinnadurai, Raghavan, Pöhlmann, Stefan, Chaipan, Chawaree, Biet, Thorsten, Peters, Thomas, Meyer, Bernd, Wilhelm, Dennis, Lu, Hong, Jing, Weiguo, Jiang, Shibo, Forssmann, Wolf-Georg, Kirchhoff, Frank

“…A variety of molecules in human blood have been implicated in the inhibition of HIV-1. However, it remained elusive which circulating natural compounds are…”
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Pituitary adenylate cyclase-activating polypeptide: a potent activator of human intestinal ion transport by Fuchs, M, Adermann, K, Raab, H R, Forssmann, W G, Kuhn, M

“…To investigate the effects of PACAP-27 on electrolyte transport across the isolated human intestinal mucosa, changes in short-circuit current (Isc) were…”
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Bronchiolar Nonciliated Secretory (Clara) Cells: Source of Guanylin in the Mammalian Lung by Cetin, Yalcin, Kulaksiz, Hasan, Redecker, Peter, Bargsten, Gerhard, Adermann, Knut, Grube, Dietrich, Forssman, Wolf-Georg

“…The peptide guanylin, which has recently been isolated from the intestine, is involved in the regulation of fluid secretion in the intestinal epithelium by…”
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Guanylin stimulates regulated secretion from human neuroendocrine pancreatic cells by John, Mathias, Wiedenmann, Bertram, Kruhøffer, Mogens, Adermann, Knut, Ankorina–Stark, Ieva, Schlatter, Eberhard, Ahnert–Hilger, Gudrun, Forssmann, Wolf–Georg, Kuhn, Michaela

“…Background & Aims: Gastroenteropancreatic neuroendocrine cells secrete chemical messengers in a calcium-dependent fashion. So far, other second messenger…”
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LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity by Krause, Alexander, Neitz, Susanne, Mägert, Hans-Jürgen, Schulz, Axel, Forssmann, Wolf-Georg, Schulz-Knappe, Peter, Adermann, Knut

“…We report the isolation and characterization of a novel human peptide with antimicrobial activity, termed LEAP-1 (liver-expressed antimicrobial peptide). Using…”
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