Search Results - "Adelroth, Pia"

Structure and Mechanism of Respiratory III–IV Supercomplexes in Bioenergetic Membranes by Brzezinski, Peter, Moe, Agnes, Ädelroth, Pia

“…In the final steps of energy conservation in aerobic organisms, free energy from electron transfer through the respiratory chain is transduced into a proton…”
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Reduction of Nitric Oxide to Nitrous Oxide in Flavodiiron Proteins: Catalytic Mechanism and Plausible Intermediates by Blomberg, Margareta R. A., Ädelroth, Pia

“…The flavin dependent nonheme diiron proteins comprise a family of enzymes, which can act as scavengers for both molecular oxygen and nitric oxide. The…”
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Structure of a functional obligate complex III2IV2 respiratory supercomplex from Mycobacterium smegmatis by Wiseman, Benjamin, Nitharwal, Ram Gopal, Fedotovskaya, Olga, Schäfer, Jacob, Guo, Hui, Kuang, Qie, Benlekbir, Samir, Sjöstrand, Dan, Ädelroth, Pia, Rubinstein, John L, Brzezinski, Peter, Högbom, Martin

“…In the mycobacterial electron-transport chain, respiratory complex III passes electrons from menaquinol to complex IV, which in turn reduces oxygen, the…”
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Reduction of molecular oxygen in flavodiiron proteins - Catalytic mechanism and comparison to heme-copper oxidases by Blomberg, Margareta R.A., Ädelroth, Pia

“…The family of flavodiiron proteins (FDPs) plays an important role in the scavenging and detoxification of both molecular oxygen and nitric oxide. Using…”
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An Engineered Glutamate in Biosynthetic Models of Heme-Copper Oxidases Drives Complete Product Selectivity by Tuning the Hydrogen-Bonding Network by Petrik, Igor D, Davydov, Roman, Kahle, Maximilian, Sandoval, Braddock, Dwaraknath, Sudharsan, Ädelroth, Pia, Hoffman, Brian, Lu, Yi

“…Efficiently carrying out the oxygen reduction reaction (ORR) is critical for many applications in biology and chemistry, such as bioenergetics and fuel cells,…”
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Extraction and liposome reconstitution of membrane proteins with their native lipids without the use of detergents by Smirnova, Irina A., Ädelroth, Pia, Brzezinski, Peter

“…Functional studies of membrane-bound channels, transporters or signal transducers require that the protein of interest resides in a membrane that separates two…”
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Insights into the structure-function relationship of the NorQ/NorD chaperones from Paracoccus denitrificans reveal shared principles of interacting MoxR AAA+/VWA domain proteins by Kahle, Maximilian, Appelgren, Sofia, Elofsson, Arne, Carroni, Marta, Ädelroth, Pia

“…NorQ, a member of the MoxR-class of AAA+ ATPases, and NorD, a protein containing a Von Willebrand Factor Type A (VWA) domain, are essential for non-heme iron…”
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Mechanisms for enzymatic reduction of nitric oxide to nitrous oxide - A comparison between nitric oxide reductase and cytochrome c oxidase by Blomberg, Margareta R.A., Ädelroth, Pia

“…Cytochrome c oxidases (CcO) reduce O2 to H2O in the respiratory chain of mitochondria and many aerobic bacteria. In addition, some species of CcO can also…”
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Modulation of protein function in membrane mimetics: Characterization of P. denitrificans cNOR in nanodiscs or liposomes by ter Beek, Josy, Kahle, Maximilian, Ädelroth, Pia

“…For detailed functional characterization, membrane proteins are usually studied in detergent. However, it is becoming clear that detergent micelles are often…”
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The insertion of the non-heme FeB cofactor into nitric oxide reductase from P. denitrificans depends on NorQ and NorD accessory proteins by Kahle, Maximilian, ter Beek, Josy, Hosler, Jonathan P., Ädelroth, Pia

“…Bacterial NO reductases (NOR) catalyze the reduction of NO into N2O, either as a step in denitrification or as a detoxification mechanism. cNOR from Paracoccus…”
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NMR Structure and Dynamics Studies of Yeast Respiratory Supercomplex Factor 2 by Zhou, Shu, Pettersson, Pontus, Huang, Jingjing, Brzezinski, Peter, Pomès, Régis, Mäler, Lena, Ädelroth, Pia

“…The Saccharomyces cerevisiae respiratory supercomplex factor 2 (Rcf2) is a 224-residue protein located in the mitochondrial inner membrane where it is involved…”
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Membrane-tethering of cytochrome c accelerates regulated cell death in yeast by Toth, Alexandra, Aufschnaiter, Andreas, Fedotovskaya, Olga, Dawitz, Hannah, Ädelroth, Pia, Büttner, Sabrina, Ott, Martin

“…Intrinsic apoptosis as a modality of regulated cell death is intimately linked to permeabilization of the outer mitochondrial membrane and subsequent release…”
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Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis by Nilsson, Tobias, Lundin, Camilla Rydström, Nordlund, Gustav, Ädelroth, Pia, von Ballmoos, Christoph, Brzezinski, Peter

“…Energy conversion in biological systems is underpinned by membrane-bound proton transporters that generate and maintain a proton electrochemical gradient…”
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NMR structural analysis of the yeast cytochrome c oxidase subunit Cox13 and its interaction with ATP by Zhou, Shu, Pettersson, Pontus, Björck, Markus L, Dawitz, Hannah, Brzezinski, Peter, Mäler, Lena, Ädelroth, Pia

“…Mitochondrial respiration is organized in a series of enzyme complexes in turn forming dynamic supercomplexes. In Saccharomyces cerevisiae (baker's yeast),…”
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Insights into the mechanism of nitric oxide reductase from a Fe B -depleted variant by Kahle, Maximilian, Blomberg, Margareta R A, Jareck, Sascha, Ädelroth, Pia

“…A key step of denitrification, the reduction of toxic nitric oxide to nitrous oxide, is catalysed by cytochrome c-dependent NO reductase (cNOR). cNOR contains…”
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Functional proton transfer pathways in the heme–copper oxidase superfamily by Lee, Hyun Ju, Reimann, Joachim, Huang, Yafei, Ädelroth, Pia

“…Heme–copper oxidases (HCuOs) terminate the respiratory chain in mitochondria and most bacteria. They are transmembrane proteins that catalyse the reduction of…”
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Design principles of proton-pumping haem-copper oxidases by Brzezinski, Peter, Ädelroth, Pia

“…Transmembrane electrochemical proton gradients are used to store free energy in biological systems, and to drive the synthesis of biomolecules and…”
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Structural and functional heterogeneity of cytochrome c oxidase in S. cerevisiae by Schäfer, Jacob, Dawitz, Hannah, Ott, Martin, Ädelroth, Pia, Brzezinski, Peter

“…Respiration in Saccharomyces cerevisiae is regulated by small proteins such as the respiratory supercomplex factors (Rcf). One of these factors (Rcf1) has been…”
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Regulatory role of the respiratory supercomplex factors in Saccharomyces cerevisiae by Lundin, Camilla Rydström, von Ballmoos, Christoph, Ott, Martin, Ädelroth, Pia, Brzezinski, Peter

“…The respiratory supercomplex factors (Rcf) 1 and 2 mediate supramolecular interactions between mitochondrial complexes III (ubiquinol-cytochrome c reductase;…”
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Functional interactions between nitrite reductase and nitric oxide reductase from Paracoccus denitrificans by Albertsson, Ingrid, Sjöholm, Johannes, ter Beek, Josy, Watmough, Nicholas J., Widengren, Jerker, Ädelroth, Pia

“…Denitrification is a microbial pathway that constitutes an important part of the nitrogen cycle on earth. Denitrifying organisms use nitrate as a terminal…”
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