Search Results - "Adegbola, RA"

Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial by Cutts, FT, Zaman, SMA, Enwere, G, Jaffar, S, Levine, OS, Okoko, JB, Oluwalana, C, Vaughan, A, Obaro, SK, Leach, A, McAdam, KP, Biney, E, Saaka, M, Onwuchekwa, U, Yallop, F, Pierce, NF, Greenwood, BM, Adegbola, RA

“…Pneumonia is estimated to cause 2 million deaths every year in children. Streptococcus pneumoniae is the most important cause of severe pneumonia. We aimed to…”
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Elimination of Haemophilus influenzae type b (Hib) disease from The Gambia after the introduction of routine immunisation with a Hib conjugate vaccine: a prospective study by Adegbola, Richard A, Secka, Ousman, Lahai, George, Lloyd-Evans, Nellie, Njie, Alpha, Usen, Stanley, Oluwalana, Claire, Obaro, Stephen, Weber, Martin, Corrah, Tumani, Mulholland, Kim, McAdam, Keith, Greenwood, Brian, Milligan, Paul JM

“…Routine immunisation of infants in The Gambia with a Haemophilus influenzae type b (Hib) polysaccharide-tetanus toxoid conjugate vaccine began in May, 1997. We…”
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DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans by Olesen, R, Wejse, C, Velez, D R, Bisseye, C, Sodemann, M, Aaby, P, Rabna, P, Worwui, A, Chapman, H, Diatta, M, Adegbola, R A, Hill, P C, Østergaard, L, Williams, S M, Sirugo, G

“…We investigated the role of DC-SIGN (CD209), long pentraxin 3 (PTX3) and vitamin D receptor (VDR) gene single nucleotide polymorphisms (SNPs) in susceptibility…”
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Bacterial Infections — A Major Cause of Death among Children in Africa by Mulholland, E. Kim, Adegbola, Richard A

“…For the past 25 years, since the United Nations Children's Fund (UNICEF) has been publishing estimates of mortality among children worldwide, the international…”
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Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum by Garton, Natalie J, Christensen, Henriette, Minnikin, David E, Adegbola, Richard A, Barer, Michael R

“…Department of Microbiology and Immunology 1 and Department of Chemistry 2 , University of Newcastle, Newcastle upon Tyne, UK MRC Laboratories, Fajara, Banjul,…”
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Timing of serotype 1 pneumococcal disease suggests the need for evaluation of a booster dose by Klugman, K.P, Madhi, S.A, Adegbola, R.A, Cutts, F, Greenwood, B, Hausdorff, W.P

“…Abstract Protection against serotype 1 could not be demonstrated in two randomized trials of 9 valent pneumococcal conjugate vaccines. An analysis of the…”
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Comparison of Enzyme-Linked Immunospot Assay and Tuberculin Skin Test in Healthy Children Exposed to Mycobacterium tuberculosis by Hill, Philip C, Brookes, Roger H, Adetifa, Ifedayo M.O, Fox, Annette, Jackson-Sillah, Dolly, Lugos, Moses D, Donkor, Simon A, Marshall, Roger J, Howie, Stephen R.C, Corrah, Tumani, Jeffries, David J, Adegbola, Richard A, McAdam, Keith P.W.J

“…To compare the enzyme-linked immunospot (ELISPOT) assay with the tuberculin skin test (TST) in children for the diagnosis of Mycobacterium tuberculosis…”
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Mycobacterium africanum Elicits an Attenuated T Cell Response to Early Secreted Antigenic Target, 6 kDa, in Patients with Tuberculosis and Their Household Contacts by de Jong, Bouke C., Hill, Philip C., Brookes, Roger H., Gagneux, Sebastien, Jeffries, David J., Otu, Jacob K., Donkor, Simon A., Fox, Annette, McAdam, Keith P. W. J., Small, Peter M., Adegbola, Richard A.

“…BackgroundMycobacterium africanum a member of the M. tuberculosis complex that is infrequently found outside of western Africa, is the cause of up to half of…”
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Carriage of pneumococci after pneumococcal vaccination by Obaro, S K, Adegbola, R A, Banya, W A, Greenwood, B M

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A randomised controlled trial of azithromycin following surgery for trachomatous trichiasis in the Gambia by Burton, M J, Kinteh, F, Jallow, O, Sillah, A, Bah, M, Faye, M, Aryee, E A N, Ikumapayi, U N, Alexander, N D E, Adegbola, R A, Faal, H, Mabey, D C W, Foster, A, Johnson, G J, Bailey, R L

“…Background/aim: Trachomatous trichiasis frequently returns following surgery. Several factors may promote recurrence: preoperative disease severity, surgeon…”
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Immunogenicity and serotype-specific efficacy of a 9-valent pneumococcal conjugate vaccine (PCV-9) determined during an efficacy trial in The Gambia by Saaka, M, Okoko, B.J, Kohberger, R.C, Jaffar, S, Enwere, G, Biney, E.E, Oluwalana, C, Vaughan, A, Zaman, S.M.A, Asthon, L, Goldblatt, D, Greenwood, B.M, Cutts, F.T, Adegbola, R.A

“…Abstract This study aimed to determine the immunogenicity of a 9-valent pneumococcal conjugate vaccine (PCV-9) in a subgroup of Gambian children enrolled in a…”
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The Long-Term Natural History of Trachomatous Trichiasis in The Gambia by Burton, Matthew J, Bowman, Richard J. C, Faal, Hannah, Aryee, Esther A. N, Ikumapayi, Usman N, Alexander, Neal D. E, Adegbola, Richard A, Mabey, David C. W, Foster, Allen, Johnson, Gordon J, Bailey, Robin L

“…Trachoma is the leading infectious cause of blindness. However, there are few data on the natural history of trachomatous trichiasis to guide program planning…”
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Fit Genotypes and Escape Variants of Subgroup III Neisseria meningitidis during Three Pandemics of Epidemic Meningitis by Zhu, Peixuan, van der Ende, Arie, Falush, Daniel, Brieske, Norbert, Morelli, Giovanna, Linz, Bodo, Popovic, Tanja, Ilse G. A. Schuurman, Adegbola, Richard A., Zurth, Kerstin, Gagneux, Sébastien, Platonov, Alexander E., Riou, Jean-Yves, Caugant, Dominique A., Nicolas, Pierre, Achtman, Mark

“…The genetic variability at six polymorphic loci was examined within a global collection of 502 isolates of subgroup III, serogroup A Neisseria meningitidis…”
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Quantitative T Cell Assay Reflects Infectious Load of Mycobacterium tuberculosis in an Endemic Case Contact Model by Hill, Philip C., Fox, Annette, Jeffries, David J., Jackson-Sillah, Dolly, Lugos, Moses D., Owiafe, Patrick K., Donkor, Simon A., Hammond, Abdulrahman S., Corrah, Tumani, Adegbola, Richard A., McAdam, Keith P. W. J., Brookes, Roger H.

“…Background. Currently, reliable efficacy markers for assessment of new interventions against tuberculosis (TB) are limited to disease and death. More precise…”
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ESAT-6/CFP-10 Fusion Protein and Peptides for Optimal Diagnosis of Mycobacterium tuberculosis Infection by Ex Vivo Enzyme-Linked Immunospot Assay in The Gambia by Hill, Philip C, Jackson-Sillah, Dolly, Fox, Annette, Franken, Kees L. M. C, Lugos, Moses D, Jeffries, David J, Donkor, Simon A, Hammond, Abdulrahman S, Adegbola, Richard A, Ottenhoff, Tom H. M, Klein, Michel R, Brookes, Roger H

“…Overlapping peptides of Mycobacterium tuberculosis antigens ESAT-6 and CFP-10 offer increased specificity over the purified protein derivative skin test when…”
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Mycobacterium africanum : a new opportunistic pathogen in HIV infection? by DE JONG, Bouke C, HILL, Philip C, BROOKES, Roger H, OTU, Jacob K, PETERSON, Kevin L, SMALL, Peter M, ADEGBOLA, Richard A

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Long term outcome of trichiasis surgery in the Gambia by Burton, M J, Bowman, R J C, Faal, H, Aryee, E A N, Ikumapayi, U N, Alexander, N D E, Adegbola, R A, West, S K, Mabey, D C W, Foster, A, Johnson, G J, Bailey, R L

“…Background: Trichiasis surgery is believed to reduce the risk of losing vision from trachoma. There are limited data on the long term outcome of surgery and…”
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Serotype-Specific Pneumococcal Antibodies in Breast Milk of Gambian Women Immunized With a Pneumococcal Polysaccharide Vaccine During Pregnancy by Obaro, Stephen K, Deubzer, Hedwig E, Newman, Vanessa O, Adegbola, Richard A, Greenwood, Brian M, Henderson, Don C

“…BACKGROUND:In breast-feeding populations, immunization during pregnancy with pneumococcal polysaccharide offers a potentially useful approach to preventing…”
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Incidence of tuberculosis and survival after its diagnosis in patients infected with HIV-1 and HIV-2 by VAN DER SANDE, Marianne A. B, SCHIM VAN DER LOEFF, Maarten F, JAYE, Assan, CORRAH, Tumani, MCCONKEY, Samuel, WHITTLE, Hilton C, BENNETT, Rachel C, DOWLING, Mary, AVEIKA, Akum A, TOGUN, Toyin O, SABALLY, Saihou, JEFFRIES, David, ADEGBOLA, Richard A, SARGE-NJIE, Ramu

“…In sub-Saharan Africa, tuberculosis (TB) is the most frequently diagnosed opportunistic infection and cause of death among HIV-infected patients. HIV-2 has…”
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Etiology of serious infections in young Gambian infants by Mulholland, E K, Ogunlesi, O O, Adegbola, R A, Weber, M, Sam, B E, Palmer, A, Manary, M J, Secka, O, Aidoo, M, Hazlett, D, Whittle, H, Greenwood, B M

“…Despite improvements in infant mortality rates in many developing countries including The Gambia, neonatal mortality remains high and many neonatal deaths are…”
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