Search Results - "Adedapo, Adeolu"
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Cardioprotective Effects of Curcumin-Nisin Based Poly Lactic Acid Nanoparticle on Myocardial Infarction in Guinea Pigs
Published in Scientific reports (09-11-2018)“…Myocardial infarction (MI) is the most prevalent cause of cardiovascular death. A possible way of preventing MI maybe by dietary supplements. The present study…”
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2
Chrysophyllum albidum fruit ethanol extract ameliorates hyperglycaemia and elevated blood pressure in streptozotocin-induced diabetic rats through modulation of oxidative stress, NF-κB and PPAR-γ
Published in Biomedicine & pharmacotherapy (01-09-2021)“…Oxidative stress and inflammation arising from hyperglycaemia have been identified as important targets in mitigating hyperglycaemia-induced organ dysfunction…”
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3
Antihypertensive effect of Phragmanthera incana (Schum) Balle on NG-nitro-L-Arginine methyl ester (L-NAME) induced hypertensive rats
Published in Journal of ethnopharmacology (15-07-2020)“…Phragmanthera incana (Schum) Balle is a member of the African mistletoes that has been reported to be used in ethnomedicine for the treatment of hypertension…”
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Ramipril mitigates Glycerol‐induced Acute Kidney Injury in Rats via its Anti‐oxidant, Anti‐renin and Anti‐apoptosis Effects
Published in The FASEB journal (01-05-2022)“…A sudden decrease in the functionality of the kidney with concomitant structural damage and functional loss is known as acute kidney injury (AKI), with some of…”
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5
The Protective Effect of the Ethanol Leaf Extract of Andrographis Paniculata on Cisplatin-Induced Acute Kidney Injury in Rats Through nrf2/KIM-1 Signalling Pathway
Published in Drug research (01-01-2018)“…The ethanol leaf extract of was used to ameliorate the renal toxicity induced by cisplatin in 28 rats divided into four groups of seven rats per group. Group A…”
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Modulatory effect of Luteolin on potassium dichromate‐induced nephrotoxicity, cardiotoxicity and genotoxicity via Kim‐1/Nrf2 signaling pathways
Published in The FASEB journal (01-05-2022)“…Environmental and occupational exposure to chromium compounds has become a potential aetiologic agent for kidney disease through excessive generation of free…”
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7
Naringenin antihypertensive power is mediated via abrogation of mineralocorticoid receptor (MCR)/ angiotensin converting enzyme (ACE)/ kidney injury molecule (Kim‐1) signaling pathway
Published in The FASEB journal (01-05-2022)“…Hypertension is a condition with chronic elevation of blood pressure and a common preventable risk factor for cardiovascular disease with attendant global…”
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Cardio-protective and antioxidant properties of caffeic acid and chlorogenic acid: Mechanistic role of angiotensin converting enzyme, cholinesterase and arginase activities in cyclosporine induced hypertensive rats
Published in Biomedicine & pharmacotherapy (01-01-2019)“…[Display omitted] •Caffeic acid (CAA) and chlorogenic acid (CHA) possessed BP reducing effect in hypertensive rats (HTR).•CAA and CHA reduced ACE,…”
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9
Clofibrate, a Peroxisome Proliferator–Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride–Induced Toxicity
Published in Biological trace element research (01-03-2022)“…Sodium fluoride (NaF) is one of the neglected environmental pollutants. It is ubiquitously found in the soil, water, and environment. Interestingly, fluoride…”
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10
Clofibrate, a PPAR‐α agonist, abrogates sodium fluoride‐induced neuroinflammation, oxidative stress, and motor incoordination via modulation of GFAP/Iba‐1/anti‐calbindin signaling pathways
Published in Environmental toxicology (01-02-2020)“…Fluoride is an environmental contaminant that is ubiquitously present in air, water, and soil. It is commonly added in minute quantity to drinking water,…”
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11
Naringin mitigates testicular injury and associated neuronal toxicity in lead-exposed cockerel chicks
Published in Avicenna journal of phytomedicine (01-01-2024)“…Lead (Pb) poisoning affects multiple organs including the reproductive system. The experiment was performed to explore the protective effect of naringin on…”
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12
Oxidative stress changes observed in selected organs of African giant rats (Cricetomys gambianus) exposed to sodium metavanadate
Published in International journal of veterinary science and medicine (01-06-2018)“…Vanadium is a contaminant of crude oil that released into the atmosphere through burning of fossil fuels. The mechanism by which it exerts toxic influences had…”
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Phytochemical screening, safety evaluation, anti-inflammatory and analgesic studies of the leaf extracts of Sterculia tragacantha
Published in Journal of complementary & integrative medicine (01-09-2016)“…Sterculia tragacantha (Sterculiaceae) is used in the treatment of boils, diarrhea, dyspepsia, fever, gonorrhea, snake bite, syphilis, and tapeworm in some West…”
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Cardiovascular and renal oxidative stress-mediated toxicities associated with bisphenol-A exposures are mitigated by Curcuma longa in rats
Published in Avicenna journal of phytomedicine (01-03-2024)“…Rhizome (CLR), due to its potent antioxidant phytochemical constituents, was investigated for its effects on bisphenol A (BPA)-induced cardiovascular and renal…”
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15
Luteolin‐mediated Kim‐1/NF‐kB/Nrf2 signaling pathways protects sodium fluoride‐induced hypertension and cardiovascular complications
Published in BioFactors (Oxford) (01-11-2018)“…The use of sodium fluoride (NaF) as a major ingredient for tooth paste, mouth wash, and mouth rinse has become inevitable in our day‐to‐day life. However,…”
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16
Kolaviron, biflavonoid complex from the seed of Garcinia kola attenuated angiotensin II- and lypopolysaccharide-induced vascular smooth muscle cell proliferation and nitric oxide production
Published in Pharmacognosy research (01-03-2016)“…Introduction: Kolaviron (KV), a biflavonoid extract from Garcinia kola seeds has been reported to possess anti-inflammatory, anti-oxidant, hepato-protective,…”
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Phytochemistry, anti-inflammatory and analgesic activities of the aqueous leaf extract of Lagenaria breviflora (Cucurbitaceae) in laboratory animals
Published in Revista de biología tropical (01-03-2013)“…The plant, and especially the fruit of Lagenaria breviflora is widely used in folklore medicine in West Africa as a herbal remedy for the treatment of human…”
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18
Antihypertensive effect of methanol leaf extract of Azadirachta indica is mediated through suppression of renal caspase 3 expressions on Nω-Nitro-l-arginine methyl ester induced hypertension
Published in Pharmacognosy research (01-10-2020)“…Background: Azadirachta indica (AI) Adr Juss (Meliaceae), known as neem, has been used traditionally for the treatment of various disease conditions including…”
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19
Luteolin mitigates potassium dichromate‐induced nephrotoxicity, cardiotoxicity and genotoxicity through modulation of Kim‐1/Nrf2 signaling pathways
Published in Environmental toxicology (01-11-2021)“…Environmental and occupational exposure to chromium compounds has become potential aetiologic agent for kidney disease with excessive generation of free…”
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20
Cardioprotective effects and antioxidant status of Andrographis paniculata in isoproterenol-induced myocardial infarction in rats
Published in Journal of Medicinal Plants for Economic Development (01-01-2019)“…Abstract only…”
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