Clinical profile and containment of the Ebola virus disease outbreak in two large West African cities, Nigeria, July–September 2014

Highlights • The outbreak, mostly a severe febrile gastroenteritis syndrome (85% fever, 70% fatigue, 65% diarrhea, 50% vomiting), was in keeping with the West Africa Ebola virus disease pattern.. • It began in Africa's most populous city and spread to a second largest city, but involved only 20...

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Bibliographic Details
Published in:	International journal of infectious diseases Vol. 53; no. C; pp. 23 - 29
Main Authors:	Ohuabunwo, Chima, Ameh, Celestine, Oduyebo, Oyin, Ahumibe, Anthony, Mutiu, Bamidele, Olayinka, Adebola, Gbadamosi, Wasiu, Garcia, Erika, Nanclares, Carolina, Famiyesin, Wale, Mohammed, Abdulaziz, Nguku, Patrick, Koko, Richard I, Obasanya, Joshua, Adebayo, Durojaye, Gbadegesin, Yemi, Idigbe, Oni, Oguntimehin, Olukayode, Nyanti, Sara, Nzuki, Charles, Abdus-Salam, Ismail, Adeyemi, Joseph, Onyekwere, Nnanna, Musa, Emmanuel, Brett-Major, David, Shuaib, Faisal, Nasidi, Abdulsalami
Format:	Journal Article
Language:	English
Published:	Canada Elsevier Ltd 01-12-2016 Elsevier
Subjects:	Adult Brain Diseases - epidemiology Brain Diseases - mortality Cities Clinical profile Diarrhea Disease Outbreaks Ebola virus disease Fatigue Female Fever Gastroenteritis Gastroenteritis - epidemiology Gastroenteritis - mortality Health Personnel Hemorrhage - epidemiology Hemorrhage - mortality Hemorrhagic fever Hemorrhagic Fever, Ebola - epidemiology Hemorrhagic Fever, Ebola - mortality Hospitalization Humans Infectious Disease Male Middle Aged Nigeria Nigeria - epidemiology Outbreak containment Pulmonary/Respiratory Vomiting World Health Organization Hemorrhagic fever Clinical profile Nigeria Gastroenteritis Ebola virus disease Outbreak containment
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Summary:	Highlights • The outbreak, mostly a severe febrile gastroenteritis syndrome (85% fever, 70% fatigue, 65% diarrhea, 50% vomiting), was in keeping with the West Africa Ebola virus disease pattern.. • It began in Africa's most populous city and spread to a second largest city, but involved only 20 cases, mostly females and health workers; no case management worker was infected. • The case fatality rate was low at 40%. • A higher mortality was seen in males, those in the older age group (≥40 years), patients with diarrhea, vomiting, or bleeding, and those presenting late to the treatment center. • Early case identification (survivors 3 ± 2 days, non-survivors 5 ± 2 days) due to effective contact tracing by epidemiologists/trainee epidemiologists, as well as prompt suspected case evaluation/isolation achieved containment within 2 months.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1201-9712 1878-3511
DOI:	10.1016/j.ijid.2016.08.011