Search Results - "Addepalli, Pavani"

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    Artificial neural network-based pharmacogenomic algorithm for warfarin dose optimization by Pavani, Addepalli, Naushad, Shaik Mohammad, Kumar, Rajasekar Manoj, Srinath, Murali, Malempati, Amaresh Rao, Kutala, Vijay Kumar

    Published in Pharmacogenomics (01-01-2016)
    “…To develop more precise pharmacogenomic algorithm for prediction of safe and effective dose of warfarin. An artificial neural network (ANN) algorithm was…”
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    Journal Article
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    Aberrations in one-carbon metabolism induce oxidative DNA damage in sporadic breast cancer by Mohammad, Naushad Shaik, Yedluri, Rupasree, Addepalli, Pavani, Gottumukkala, Suryanarayana Raju, Digumarti, Raghunadha Rao, Kutala, Vijay Kumar

    Published in Molecular and cellular biochemistry (01-03-2011)
    “…The authors investigated the role of dietary micronutrients and eight functional polymorphisms of one-carbon metabolism in modulating oxidative stress in…”
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    Development of neuro-fuzzy model to explore gene-nutrient interactions modulating warfarin dose requirement by Pavani, Addepalli, Naushad, Shaik Mohammad, Lakshmitha, Ganapathy, Nivetha, Sriraman, Stanley, Balraj Alex, Malempati, Amaresh Rao, Kutala, Vijay Kumar

    Published in Pharmacogenomics (01-08-2016)
    “…To investigate the influence of alterations in vitamin K (K1, K2 and K3) in modulating warfarin dose requirement. Reverse phase HPLC to determine the plasma…”
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    Clinical utility of polymorphisms in one-carbon metabolism for breast cancer risk prediction by Naushad, Shaik Mohammad, Divyya, Shree, Pavani, Addepalli, Rupasree, Yedluri, Digumarti, Raghunadha Rao, Gottumukkala, Suryanarayana Raju, Kutala, Vijay Kumar

    Published in Journal of medical and allied sciences (31-01-2011)
    “…This study addresses the issues in translating the laboratory derived data obtained during discovery phase of research to a clinical setting using a breast…”
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    Journal Article
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    Recipient ABCB1, donor and recipient CYP3A5 genotypes influence tacrolimus pharmacokinetics in liver transplant cases by Naushad, Shaik Mohammad, Pavani, Addepalli, Rupasree, Yedluri, Hussain, Tajamul, Alrokayan, Salman A, Kutala, Vijay Kumar

    Published in Pharmacological reports (01-06-2019)
    “…Effective immunosuppression through optimization of trough levels tacrolimus reduces post-transplant mortality rate in liver transplant cases. Meta-analysis…”
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    Epistatic interactions between loci of one-carbon metabolism modulate susceptibility to breast cancer by Naushad, Shaik Mohammad, Pavani, Addepalli, Digumarti, Raghunadha Rao, Gottumukkala, Suryanarayana Raju, Kutala, Vijay Kumar

    Published in Molecular biology reports (01-11-2011)
    “…In view of growing body of evidence substantiating the role of aberrations in one-carbon metabolism in the pathophysiology of breast cancer and lack of studies…”
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  8. 8

    Methodological issues in the development of a pharmacogenomic algorithm for warfarin dosing: comparison of two regression approaches by Pavani, Addepalli, Naushad, Shaik Mohammad, Uma, Addepally, Kutala, Vijay Kumar

    Published in Pharmacogenomics (01-06-2014)
    “…To ascertain whether multiple polynomial regression (MPR) has any advantage over multiple linear regression (MLR) in developing pharmacogenomic algorithms. Two…”
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    Journal Article
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    Association of aberrations in one-carbon metabolism with molecular phenotype and grade of breast cancer by Naushad, Shaik Mohammad, Pavani, Addepalli, Rupasree, Yedluri, Divyya, Shree, Deepti, Sripurna, Digumarti, Raghunadha Rao, Gottumukkala, Suryanarayana Raju, Prayaga, Aruna, Kutala, Vijay Kumar

    Published in Molecular carcinogenesis (01-10-2012)
    “…We have earlier demonstrated the role of aberrant one‐carbon metabolism in the etiology of breast cancer. In the current study, we examine the clinical utility…”
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    Mechanistic insights into the effect of CYP2C92 and CYP2C93 variants on the 7-hydroxylation of warfarin by Pavani, Addepalli, Naushad, Shaik Mohammad, Stanley, Balraj Alex, Kamakshi, Renganathan Gnanambal, Abinaya, Krishnan, Amaresh Rao, Malempati, Uma, Addepally, Kutala, Vijay Kumar

    Published in Pharmacogenomics (01-03-2015)
    “…To evaluate the impact of CYP2C9*2 and CYP2C9*3 variants on binding and hydroxylation of warfarin. Multiple linear regression model of warfarin…”
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    Journal Article
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    Retrospective evidence for clinical validity of expanded genetic model in warfarin dose optimization in a South Indian population by Pavani, Addepalli, Naushad, Shaik Mohammad, Mishra, Ramesh C, Malempati, Amaresh Rao, Pinjala, Ramakrishna, Kumar, Takallapally Ramesh, Kutala, Vijay Kumar

    Published in Pharmacogenomics (01-06-2012)
    “…To optimize warfarin dose in patients at risk for thrombotic events, we have recently developed a pharmacogenomic algorithm, which explained 44.9% of the…”
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    Journal Article
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    Mechanistic insights into the effect of by Pavani, Addepalli, Naushad, Shaik Mohammad, Stanley, Balraj Alex, Kamakshi, Renganathan Gnanambal, Abinaya, Krishnan, Amaresh Rao, Malempati, Uma, Addepally, Kutala, Vijay Kumar

    Published in Pharmacogenomics (01-03-2015)
    “…To evaluate the impact of and variants on binding and hydroxylation of warfarin. Multiple linear regression model of warfarin pharmacokinetics was developed…”
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    Journal Article
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