Search Results - "Aday, Sezin"

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells by Cecchelli, Romeo, Aday, Sezin, Sevin, Emmanuel, Almeida, Catarina, Culot, Maxime, Dehouck, Lucie, Coisne, Caroline, Engelhardt, Britta, Dehouck, Marie-Pierre, Ferreira, Lino

“…The human blood brain barrier (BBB) is a selective barrier formed by human brain endothelial cells (hBECs), which is important to ensure adequate neuronal…”
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Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition by Aday, Sezin, Zoldan, Janet, Besnier, Marie, Carreto, Laura, Saif, Jaimy, Fernandes, Rui, Santos, Tiago, Bernardino, Liliana, Langer, Robert, Emanueli, Costanza, Ferreira, Lino

“…Several cell-based therapies are under pre-clinical and clinical evaluation for the treatment of ischemic diseases. Poor survival and vascular engraftment…”
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Heparin-functionalized chitosan scaffolds for bone tissue engineering by Gümüşderelioğlu, Menemşe, Aday, Sezin

“…The aim of this study is to investigate the effects of heparin-functionalized chitosan scaffolds on the activity of preosteoblasts. The chitosan scaffolds…”
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An in vitro Blood-brain Barrier Model to Study the Penetration of Nanoparticles by Aday, Sezin, Li, Wen, Karp, Jeffrey M, Joshi, Nitin

“…The blood-brain barrier (BBB), a crucial protection mechanism in the central nervous system (CNS), is a selective barrier comprised of endothelial cells. It…”
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Controlling the Neuronal Differentiation of Stem Cells by the Intracellular Delivery of Retinoic Acid-Loaded Nanoparticles by Maia, João, Santos, Tiago, Aday, Sezin, Agasse, Fabienne, Cortes, Luísa, Malva, João O, Bernardino, Liliana, Ferreira, Lino

“…The manipulation of endogenous stem cell populations from the subventricular zone (SVZ), a neurogenic niche, creates an opportunity to induce neurogenesis and…”
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Ultrasound‐mediated delivery of flexibility‐tunable polymer drug conjugates for treating glioblastoma by Sun, Tao, Krishnan, Vinu, Pan, Daniel C., Filippov, Sergey K., Ravid, Sagi, Sarode, Apoorva, Kim, Jayoung, Zhang, Yongzhi, Power, Chanikarn, Aday, Sezin, Guo, Junling, Karp, Jeffrey M., McDannold, Nathan J., Mitragotri, Samir S.

“…Effective chemotherapy delivery for glioblastoma multiforme (GBM) is limited by drug transport across the blood–brain barrier and poor efficacy of single…”
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Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration by Fernandes, Hugo, Zonnari, Alessandra, Abreu, Ricardo, Aday, Sezin, Barão, Marta, Albino, Inês, Lino, Miguel, Branco, Ana, Seabra, Cátia, Barata, Tânia, Leal, Ermelindo C., Tralhão, José Guilherme, Gonçalves, Lino, de Jong, Alwin, Peters, Hendrika A.B., de Vries, Margreet R., da Costa Martins, Paula, Quax, Paul H.A., Ferreira, Lino

“…Endothelial cell (EC) activity is essential for tissue regeneration in several (patho)physiological contexts. However, our capacity to deliver in vivo…”
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Analysis of Neat Biofluids Obtained During Cardiac Surgery Using Nanoparticle Tracking Analysis: Methodological Considerations by Shearn, Andrew I U, Aday, Sezin, Ben-Aicha, Soumaya, Carnell-Morris, Pauline, Siupa, Agnieszka, Angelini, Gianni D, Clayton, Aled, Boulanger, Chantal, Punjabi, Prakash, Emanueli, Costanza, Biglino, Giovanni

“…Small extracellular vesicles (sEVs) are those nanovesicles 30-150 nm in size with a role in cell signalling and potential as biomarkers of disease…”
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A cost-effective and simple culture method for primary hepatocytes by Aday, Sezin, Ege University, Izmir, Turkey, Hasirci, Nesrin, Middle East Technical University, Ankara, Turkey, Deliloglu Gurhan, Ismet, Ege University, Izmir, Turkey

“…Hepatocytes, the major epithelial cells of the liver, maintain their morphology in culture dishes coated with extracellular matrix (ECM) components such as…”
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Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo by Aday, Sezin, Hazan-Halevy, Inbal, Chamorro-Jorganes, Aranzazu, Anwar, Maryam, Goldsmith, Meir, Beazley-Long, Nicholas, Sahoo, Susmita, Dogra, Navneet, Sweaad, Walid, Catapano, Francesco, Ozaki-Tan, Sho, Angelini, Gianni D., Madeddu, Paolo, Benest, Andrew V., Peer, Dan, Emanueli, Costanza

“…MicroRNAs (miRNAs) regulate gene expression by post-transcriptional inhibition of target genes. Proangiogenic small extracellular vesicles (sEVs; popularly…”
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BBB pathophysiology-independent delivery of siRNA in traumatic brain injury by Li, Wen, Qiu, Jianhua, Li, Xiang-Ling, Aday, Sezin, Zhang, Jingdong, Conley, Grace, Xu, Jun, Joseph, John, Lan, Haoyue, Langer, Robert, Mannix, Rebekah, Karp, Jeffrey M, Joshi, Nitin

“…Small interfering RNA (siRNA)-based therapeutics can mitigate the long-term sequelae of traumatic brain injury (TBI) but suffer from poor permeability across…”
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Abstract 13859: The Omics Signature of Human Pericardial Fluid Exosomes Reveals the Therapeutic Potential of APAF-1 Inhibition in Ischemic Heart Disease by Bellahcene, Mohamed, Saif, Jaimy, Sarkar, Moumita, Anwar, Maryam, Aday, Sezin, Sedani, Sunny, Guan, Yingshu, Chamorro-Jorganes, Aranzazu, Ruiz Polo de Lara, Inigo, Heesom, Kate, angelini, gianni, Punjabi, Prakash, Peer, Dan, Emanueli, Costanza

“…Abstract only Background: The human pericardial fluid (PF) contains heart-derived small extracellular vesicles (sEVs) able to induce vascular responses via…”
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Abstract 130: Development of Bioinspired Synthetic Exosomes With Proangiogenic Potential by Aday, Sezin, Halevy, Inbal, Anwar, Maryam, Madeddu, Paolo, Sahoo, Susmita, Petretto, Enrico, Peer, Dan, Emanueli, Costanza

“…Abstract only Exosomes with variable microRNA cargos are released from different cell types and stimulate angiogenesis in animal models. Therefore, exosomes…”
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Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential by Comune, Michela, Rai, Akhilesh, Chereddy, Kiran K., Pinto, Sandra, Aday, Sezin, Ferreira, André F., Zonari, Alessandra, Blersch, Josephine, Cunha, Rodrigo, Rodrigues, Ricardo, Lerma, Juan, Simões, Pedro N., Préat, Veronique, Ferreira, Lino

“…Chronic skin wounds affect ≈3% of persons aged >60years (Davies et al., 2007) [1]. These wounds are typically difficult to heal by conventional therapies and…”
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miR-210 Enhances the Therapeutic Potential of Bone-Marrow-Derived Circulating Proangiogenic Cells in the Setting of Limb Ischemia by Besnier, Marie, Gasparino, Stefano, Vono, Rosa, Sangalli, Elena, Facoetti, Amanda, Bollati, Valentina, Cantone, Laura, Zaccagnini, Germana, Maimone, Biagina, Fuschi, Paola, Da Silva, Daniel, Schiavulli, Michele, Aday, Sezin, Caputo, Massimo, Madeddu, Paolo, Emanueli, Costanza, Martelli, Fabio, Spinetti, Gaia

“…Therapies based on circulating proangiogenic cells (PACs) have shown promise in ischemic disease models but require further optimization to reach the bedside…”
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Endothelial progenitor cells enhance blood-brain barrier permeability in subacute stroke by Sargento-Freitas, João, Aday, Sezin, Nunes, César, Cordeiro, Miguel, Gouveia, Ana, Silva, Fernando, Machado, Cristina, Rodrigues, Bruno, Santo, Gustavo Cordeiro, Ferreira, Carlos, Amorim, André, Sousa, Susana, Gomes, Ana Catarina, Castelo-Branco, Miguel, Ferreira, Lino, Cunha, Luís

“…To study the association among endothelial progenitor cells (EPCs), subacute blood-brain barrier (BBB) permeability, and clinical outcome after ischemic…”
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Abstract 10: MicroRNA 17 in Angiogenesis: Lessons Learned From Immobilized Vascular Endothelial Growth Factor by Aday, Sezin, Besnier, Marie, Zoldan, Janet, Saif, Jaimy, Santos, Tiago, Carreto, Laura, Bernardino, Liliana, Langer, Robert, Emanueli, Costanza, Ferreira, Lino

“…Abstract only Several pre-clinical and clinical studies are exploring the therapeutic effect of cell-based therapies in ischemic diseases, including Peripheral…”
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Endothelial Progenitor Cells influence acute and subacute stroke hemodynamics by Sargento-Freitas, João, Aday, Sezin, Nunes, César, Cordeiro, Miguel, Gouveia, Ana, Silva, Fernando, Machado, Cristina, Rodrigues, Bruno, Santo, Gustavo Cordeiro, Ferreira, Carlos, Castelo-Branco, Miguel, Ferreira, Lino, Cunha, Luís

“…Endothelial Progenitor Cells (EPCs) are a circulating stem cell population with in vivo capacity of promoting angiogenesis after ischemic events. Despite the…”
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Lysophosphatidic acid enhances survival of human CD34+ cells in ischemic conditions by Kostic, Ivana, Fidalgo-Carvalho, Isabel, Aday, Sezin, Vazão, Helena, Carvalheiro, Tiago, Grãos, Mário, Duarte, António, Cardoso, Carla, Gonçalves, Lino, Carvalho, Lina, Paiva, Artur, Ferreira, Lino

“…Several clinical trials are exploring therapeutic effect of human CD34 + cells in ischemic diseases, including myocardial infarction. Unfortunately, most of…”
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Bone-like apatite-coated chitosan scaffolds: Characterization and osteoblastic activity by Aday, Sezin, Gümüşderelioğlu, Menemşe

“…In this study, porous scaffolds were prepared from chitosan (2% w/v in acetic acid and deacetylation degree: DD > 85%) by freeze‐drying method, and freshly…”
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