Search Results - "Adamson, I Y"

Acute pulmonary toxicity of urban particulate matter and ozone by Vincent, R, Bjarnason, SG, Adamson, IY, Hedgecock, C, Kumarathasan, P, Guenette, J, Potvin, M, Goegan, P, Bouthillier, L

“…We have investigated the acute lung toxicity of urban particulate matter in interaction with ozone. Rats were exposed for 4 hours to clean air, ozone (0.8…”
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Collagenase and gelatinase activities in bronchoalveolar lavage fluids during bleomycin-induced lung injury by Bakowska, J., Adamson, I. Y. R.

“…Basement membrane degradation can be indicative of tissue injury, but the process may also release matrix‐bound cytokines to stimulate cell regeneration. To…”
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COMPARATIVE PULMONARY TOXICITY OF VARIOUS SOLUBLE METALS FOUND IN URBAN PARTICULATE DUSTS by Prieditis, H., Adamson, I. Y. R.

“…The potential toxicity of an atmospheric dust sample EHC-93 has been attributed to the soluble fraction and, more specifically, to the zinc component. The…”
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Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis by Adamson, IY, Young, L, Bowden, DH

“…Explants of mouse lung were cultured at various stages of injury after exposure to hyperoxia for determination of whether endothelial or epithelial injury…”
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DIFFERENTIAL PRODUCTION OF METALLOPROTEINASES AFTER INSTILLING VARIOUS URBAN AIR PARTICLE SAMPLES TO RAT LUNG by Adamson, I. Y. R., Vincent, R., Bakowska, J.

“…To test the hypothesis that the development of tracheal stenosis would depend on the extent of tracheal cartilaginous injury, either 90° (n=6) or 180° (n=6) of…”
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Epithelial cell-fibroblast interactions in lung injury and repair by Adamson, IY, Hedgecock, C, Bowden, DH

“…Although direct intercellular contacts between alveolar epithelial cells and fibroblasts have been described in developing and adult lung, the frequency of…”
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Early Mesothelial Cell Proliferation after Asbestos Exposure: In Vivo and in Vitro Studies by Adamson, I Y

“…There is some evidence that proliferation of pleural mesothelial cells (MC) occurs soon after deposition of asbestos fibers. To study this effect, we instilled…”
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Zinc Is the Toxic Factor in the Lung Response to an Atmospheric Particulate Sample by Adamson, I.Y.R., Prieditis, H., Hedgecock, C., Vincent, R.

“…The atmospheric dust sample EHC-93 is known to induce lung cell injury and inflammation in which the toxicity has been attributed to a soluble component,…”
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Alveolar macrophage kinetics and multinucleated giant cell formation after lung injury by Prieditis, H., Adamson, I. Y. R.

“…Multinucleated giant cells (MGC) are a prominent feature of some chronic inflammatory states in the lung. These cells are formed by macrophage fusion, but how…”
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Mesothelial cell proliferation: a nonspecific response to lung injury associated with fibrosis by Adamson, I Y, Bakowska, J, Bowden, D H

“…An early proliferative response of mesothelial and subpleural cells has been reported in animals after inhalation or intratracheal (I.T.) instillation to the…”
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Alveolar type II cell growth on a pulmonary endothelial extracellular matrix by Adamson, I Y, Young, L

“…Most of the alveolar epithelium overlies a fused basement membrane produced by epithelial and endothelial cells. To determine how this type of matrix…”
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Pulmonary Toxicity of an Atmospheric Particulate Sample Is Due to the Soluble Fraction by Adamson, Ian Y.R., Prieditis, Heather, Vincent, Renaud

“…Adverse health effects have been associated with the inhalation of a variety of atmospheric particles. The potential toxicity of a recently collected urban air…”
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Cellular kinetics in the lungs of aging Fischer 344 rats after acute exposure to ozone by Vincent, R, Adamson, IY

“…Lung repair in aging Fischer 344 male rats was investigated after an acute inhalation exposure to ozone. Adult (9-month-old) and senescent (24-month-old) rats…”
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Mesothelial cell proliferation after instillation of long or short asbestos fibers into mouse lung by Adamson, IY, Bakowska, J, Bowden, DH

“…The relationship of asbestos deposition in the lung to subsequent cell proliferation at the pleural surface is not clear. The present study examines DNA…”
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Acute Effects of Inhaled Urban Particles and Ozone : Lung Morphology, Macrophage Activity, and Plasma Endothelin-1 by Bouthillier, Leo, Vincent, Renaud, Goegan, Patrick, Adamson, Ian Y. R, Bjarnason, Stephen, Stewart, Mark, Guenette, Josee, Potvin, Marc, Kumarathasan, Prem

“…We studied acute responses of rat lungs to inhalation of urban particulate matter and ozone. Exposure to particles (40 mg/m3 for 4 hours; mass median…”
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Enhanced alveolar type II cell growth on a pulmonary extracellular matrix over fibroblasts by Adamson, I Y, Young, L, Bakowska, J

“…The growth of alveolar type II cells was studied when these cells were maintained for 2 days on a pulmonary endothelium-derived extracellular matrix (ECM) on a…”
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KGF AND HGF ARE GROWTH FACTORS FOR MESOTHELIAL CELLS IN PLEURAL LAVAGE FLUID AFTER INTRATRACHEAL ASBESTOS by ADAMSON, I. Y. R, BAKOWSKA, J

“…Mesothelial cells proliferate soon after asbestos deposition in the lung. The present study investigates whether the known mesothelial cell mitogens…”
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Instillation of chemotactic factor to silica-injected lungs lowers interstitial particle content and reduces pulmonary fibrosis by Adamson, IY, Prieditis, H, Bowden, DH

“…Silica-induced pulmonary fibrosis usually follows exposure to increased levels of this particulate and its retention in interstitial macrophages of the lung…”
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Lung mesothelial cell and fibroblast responses to pleural and alveolar macrophage supernatants and to lavage fluids from crocidolite-exposed rats by Adamson, I Y, Prieditis, H, Young, L

“…An early phase of proliferation by mesothelial cells and fibroblasts occurs in the lung after asbestos deposition, but the source and identity of the…”
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Degradation of type IV collagen during the development of fetal rat lung by Arden, M G, Spearman, M A, Adamson, I Y

“…Lung structure undergoes rapid remodeling during late gestation as a functional respiratory unit is formed. To determine the role of collagen turnover in this…”
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