Search Results - "Adamson, Ella C."
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Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations
Published in Experimental hematology (01-02-2024)“…•In acute myeloid leukemia and myeloproliferative/myelodysplastic disorders, loss of function (LOF) mutations in EZH2 result in lower H3K27 methylation•EZH2…”
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A chemical probe to modulate human GID4 Pro/N-degron interactions
Published in Nature chemical biology (01-09-2024)“…The C-terminal to LisH (CTLH) complex is a ubiquitin ligase complex that recognizes substrates with Pro/N-degrons via its substrate receptor Glucose-Induced…”
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Journal Article