Search Results - "Adamson, E D"

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFβ1, PTEN, p53, and fibronectin by Baron, V, Adamson, E D, Calogero, A, Ragona, G, Mercola, D

“…Recent studies are reviewed indicating that the transcription factor early growth response-1 (Egr1) is a direct regulator of multiple tumor suppressors…”
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A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells by Yu, J, Baron, V, Mercola, D, Mustelin, T, Adamson, E D

“…p73, a transcription factor rarely mutated in cancer, regulates a subset of p53 target genes that cause cells to respond to genotoxic stress by growth arrest…”
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Decreased Egr‐1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation by Huang, Ruo‐Pan, Fan, Yan, De Belle, Ian, Niemeyer, Christina, Gottardis, Marco M., Mercola, Dan, Adamson, Eileen D.

“…We have examined several types of tumor cell lines and shown that they invariably expressed little or no Egr‐1, in contrast to their normal counterparts. We…”
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Targeted Disruption of Vinculin Genes in F9 and Embryonic Stem Cells Changes Cell Morphology, Adhesion, and Locomotion by J.-L. Coll, A. Ben-Ze'ev, Ezzell, R. M., J. L. Rodriguez Fernandez, Baribault, H., Oshima, R. G., Adamson, E. D.

“…Vinculin, a major constituent of focal adhesions and zonula adherens junctions, is thought to be involved in linking the microfilaments to areas of…”
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UV Activates Growth Factor Receptors via Reactive Oxygen Intermediates by Huang, Ruo-Pan, Wu, Jie-Xin, Fan, Yan, Adamson, Eileen D.

“…Exposure of mammalian cells to UV irradiation induces rapid and transient expression of early growth response-1 gene (Egr-1) encoding a transcription factor…”
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Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain by RUO-PAN HUANG, CHAOTING LIU, YAN FAN, DAN MERCOLA, ADAMSON, E. D

“…Human HT1080 fibrosarcoma cells, subclone H4, express little or no Egr-1 (Zif/268, Krox 24), an early growth response gene encoding a transcription factor…”
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Differences in Elasticity of Vinculin-Deficient F9 Cells Measured by Magnetometry and Atomic Force Microscopy by Goldmann, Wolfgang H., Galneder, Reinhard, Ludwig, Markus, Xu, Weiming, Adamson, Eileen D., Wang, Ning, Ezzell, Robert M.

“…We have investigated a mouse F9 embryonic carcinoma cell line, in which both vinculin genes were inactivated by homologous recombination, that exhibits…”
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Activities of growth factors in preimplantation embryos by Adamson, E D

“…The development of the mammalian preimplantation embryo in vitro occurs more slowly and less successfully compared to development in the uterus. The fact that…”
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Oncogenes in development by Adamson, E D

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Method for cloning in vivo targets of the Egr-1 transcription factor by de Belle, I, Mercola, D, Adamson, E D

“…A methodology is described that allows the in vivo trapping of transcription factors to their target regulatory elements in multiple genes simultaneously…”
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The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling by de Belle, Ian, Virolle, Thierry, Adamson, Eileen D, Baron, Veronique, Birle, Diana, Mercola, Dan, Mustelin, Tomas

“…The PTEN tumour suppressor and pro-apoptotic gene is frequently mutated in human cancers. We show that PTEN transcription is upregulated by Egr-1 after…”
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Characterization of the DNA-binding properties of the early growth response-1 (Egr-1) transcription factor: evidence for modulation by a redox mechanism by Huang, R P, Adamson, E D

“…The binding of the transcription factor early growth response-1 (Egr-1) to its specific DNA-binding sequence GCGGGGGCG occurs through the interaction of three…”
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Suppression of v-sis-dependent transformation by the transcription factor, Egr-1 by Huang, R P, Darland, T, Okamura, D, Mercola, D, Adamson, E D

“…The transcription factor Egr-1, stimulates the activity of a number of genes and inhibits other genes, by binding to the sequence GCGGGGGCG in 5' enhancer…”
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The heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene by Andrews, G K, Harding, M A, Calvet, J P, Adamson, E D

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Preneoplastic mammary tumor markers: Cripto and amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice by Niemeyer, Christina C., Spencer‐Dene, Bradley, Wu, Jie‐Xin, Adamson, Eileen D.

“…Amphiregulin (Ar) and Cripto (Cr) are autocrine growth factors for mammary cells and both have been observed to exhibit high expression in human mammary…”
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Epidermal growth factor receptor mRNA and protein increase after the four-cell preimplantation stage in murine development by Wiley, Lynn M., Wu, Jie-Xin, Harari, Ilana, Adamson, Eileen D.

“…Epidermal growth factor receptors (EGF-Rs) are expressed at increasing levels on mouse preimplantation embryos. Immunofluorescence assays were used to show…”
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Vinculin knockout results in heart and brain defects during embryonic development by Xu, W, Baribault, H, Adamson, E D

“…The vinculin gene codes for a cytoskeletal protein, found in focal adhesion plaques and in cell-cell adherens junctions. Vinculin was inactivated by homologous…”
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Suppression of human fibrosarcoma cell growth by transcription factor, Egr‐1, involves down‐regulation of Bcl‐2 by Huang, Ruo‐Pan, Fan, Yan, Peng, Ao, Zeng, Zi‐Li, Reed, John C., Adamson, Eileen D., Boynton, Alton L.

“…Previously, we showed that the transcription factor Egr‐1 suppressed the proliferation of v‐sis transformed NIH3T3 cells and also a number of human tumor…”
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The EGFR gene family in embryonic cell activities by Adamson, E D, Wiley, L M

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α-Catenin-Vinculin Interaction Functions to Organize the Apical Junctional Complex in Epithelial Cells by Watabe-Uchida, Mitsuko, Uchida, Naoshige, Imamura, Yuzo, Nagafuchi, Akira, Fujimoto, Kazushi, Uemura, Tadashi, Vermeulen, Stefan, van Roy, Frans, Adamson, Eileen D., Takeichi, Masatoshi

“…αE-catenin, a cadherin-associated protein, is required for tight junction (TJ) organization, but its role is poorly understood. We transfected an…”
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