Search Results - "Adams, Sharon D"

HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia by Zaimoku, Yoshitaka, Patel, Bhavisha A., Adams, Sharon D., Shalhoub, Ruba, Groarke, Emma M., Lee, Audrey Ai Chin, Kajigaya, Sachiko, Feng, Xingmin, Rios, Olga Julia, Eager, Holly, Alemu, Lemlem, Quinones Raffo, Diego, Wu, Colin O., Flegel, Willy A., Young, Neal S.

“…Immune aplastic anemia (AA) features somatic loss of HLA class I allele expression on bone marrow cells, consistent with a mechanism of escape from…”
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The impact of pre-existing HLA and red blood cell antibodies on transfusion support and engraftment in sickle cell disease after nonmyeloablative hematopoietic stem cell transplantation from HLA-matched sibling donors: A prospective, single-center, observational study by Nickel, Robert Sheppard, Flegel, Willy A., Adams, Sharon D., Hendrickson, Jeanne E., Liang, Hua, Tisdale, John F., Hsieh, Matthew M.

“…Hematopoietic stem cell transplantation (HSCT) is curative for patients with sickle cell disease (SCD). Prior to HSCT, patients with SCD commonly receive RBC…”
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Ambiguous allele combinations in HLA Class I and Class II sequence-based typing: when precise nucleotide sequencing leads to imprecise allele identification by Adams, Sharon D, Barracchini, Kathleen C, Chen, Deborah, Robbins, FuMeei, Wang, Lu, Larsen, Paula, Luhm, Robert, Stroncek, David F

“…Sequence-based typing (SBT) is one of the most comprehensive methods utilized for HLA typing. However, one of the inherent problems with this typing method is…”
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A pilot trial of complement inhibition using eculizumab to overcome platelet transfusion refractoriness in human leukocyte antigen allo‐immunized patients by Vo, Phuong, Purev, Enkhtsetseg, West, Kamille A., McDuffee, Emily, Worthy, Tatyana, Cook, Lisa, Hawks, Geri, Wells, Brian, Shalabi, Reem, Flegel, Willy A., Adams, Sharon D., Reger, Robert, Aue, Georg, Tian, Xin, Childs, Richard

“…Summary Heavily transfused patients frequently develop human leukocyte antigen (HLA) allo‐immunization resulting in platelet transfusion refractoriness and a…”
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Combined haploidentical and cord blood transplantation for refractory severe aplastic anaemia and hypoplastic myelodysplastic syndrome by Childs, Richard W., Tian, Xin, Vo, Phuong, Purev, Enkhtsetseg, Kotecha, Ritesh R., Carlsten, Mattias, Clara, Joseph, Flegel, Willy A., Adams, Sharon D., Khuu, Hanh M., Stroncek, David F., Cook, Lisa, Worthy, Tat’yana, Geller, Nancy L., Wells, Brian, Wilder, Jennifer, Reger, Robert, Aue, Georg

“…Summary Umbilical cord blood (UCB) transplantation is a potentially curative treatment for patients with refractory severe aplastic anaemia (SAA), but has…”
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Revisiting the association of HLA alleles and haplotypes with CYP21A2 mutations in a large cohort of patients with congenital adrenal hyperplasia by Jayakrishnan, Rahul, Lao, Qizong, Adams, Sharon D., Ward, William W., Merke, Deborah P.

“…The CYP21A2 gene encoding 21‑hydroxylase is on chromosome 6p21.3 within the human leukocyte antigen (HLA) class III major histocompatibility complex and an…”
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The effect of cigarette smoking on the clinical and serological phenotypes of polymyositis and dermatomyositis by Schiffenbauer, Adam, Faghihi-Kashani, Sara, O'Hanlon, Terrence P., Flegel, Willy A., Adams, Sharon D., Targoff, Ira N., Oddis, Chester V., Ytterberg, Steven R., Aggarwal, Rohit, Christopher-Stine, Lisa, Shamim, Ejaz A., Dellaripa, Paul F., Danoff, Sonye K., Mammen, Andrew L., Miller, Frederick W.

“…Cigarette smoking is associated with immune-mediated disorders. We explored the contribution of smoking to polymyositis (PM) and dermatomyositis (DM)…”
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Integrating pharmacogenetic information and clinical decision support into the electronic health record by Goldspiel, Barry R, Flegel, Willy A, DiPatrizio, Gary, Sissung, Tristan, Adams, Sharon D, Penzak, Scott R, Biesecker, Leslie G, Fleisher, Thomas A, Patel, Jharana J, Herion, David, Figg, William D, Lertora, Juan J L, McKeeby, Jon W

“…Pharmacogenetics (PG) examines gene variations for drug disposition, response, or toxicity. At the National Institutes of Health Clinical Center (NIH CC), a…”
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Pharmacogenomics Implementation at the National Institutes of Health Clinical Center by Sissung, Tristan M., McKeeby, Jon W., Patel, Jharana, Lertora, Juan J., Kumar, Parag, Flegel, Willy A., Adams, Sharon D., Eckes, Ellen J., Mickey, Frank, Plona, Teri M., Mellott, Stephanie D., Baugher, Ryan N., Wu, Xiaolin, Soppet, Daniel R., Barcus, Mary E., Datta, Vivekananda, Pike, Kristen M., DiPatrizio, Gary, Figg, William D., Goldspiel, Barry R.

“…The National Institutes of Health Clinical Center (NIH CC) is the largest hospital in the United States devoted entirely to clinical research, with a highly…”
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P018 Evaluation of labtype CWD and XR assays utilizing labscan3d for high throughput/resolution HLA typing by Levy, Kimberly Y, Barracchini, Kathleen C, Adams, Sharon D, Flegel, Willy A

“…Aim High resolution HLA typing with clinical applications is preferred in some applications of transfusion and transplantation medicine. Concordance of results…”
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P064 by Yuan, Yao, Adams, Sharon D, Dinauer, David M, Rosenau, Christopher M, Uribe, Marcela R, Flegel, Willy A

“…Aim To develop assays to quantify the mRNA transcribed from 15 KIR functional genes utilizing a quantitative real-time PCR (qPCR) method. To study the KIR mRNA…”
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98-P by Yuan, Yao, Adams, Sharon D, Dinauer, David M, Rosenau, Christopher M, Uribe, Marcela R, Flegel, Willy A

“…Aim To develop assays to quantify the mRNA transcribed from KIR genes utilizing a quantitative real-time PCR (qPCR) method. To study the KIR mRNA expression…”
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51-OR by Tremblay, Christine A, Uribe, Marcela R, Peaceman, Daniel, Salit, Rachel B, Pavletic, Steven, Adams, Sharon D, Flegel, Willy A

“…Aim The goal of the study was to evaluate a correlation of an HLA restricted minor histocompatibility antigen (mHAg) with the development of graft versus host…”
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118-P Allele frequency assessment of 18 minor histocompatibility antigens (Mhags) in African Americans by Bakker, Gina R, Uribe, Marcela R, Adams, Sharon D, Flegel, Willy A

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Comprehensive epitope mapping of the Epstein-Barr virus latent membrane protein-2 in normal, non tumor-bearing individuals by Provenzano, Maurizio, Selleri, Silvia, Jin, Ping, Wang, Ena, Werden, Rosemary, Slezak, Stephanie, Adams, Sharon D, Panelli, Monica C, Leitman, Susan F, Stroncek, David F, Marincola, Francesco M

“…Latent membrane protein (LMP)-2 is one of the Epstein-Barr virus (EBV)-encoded proteins consistently expressed by nasopharyngeal carcinoma (NPC)…”
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Human Leukocyte Antigen Alleles Associated with Interstitial Lung Disease in North Americans with Idiopathic Inflammatory Myopathy by Johnson, Cheilonda, Schiffenbauer, Adam I, Miller, Frederick W, Perin, Jamie, Danoff, Sonye K, Diwadkar, Avantika R, Joo, Jaehyun, Himes, Blanca E, Meyer, Nuala J

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Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia by Zaimoku, Yoshitaka, Adams, Sharon D., Patel, Bhavisha A, Lee, Audrey Ai Chin, Kajigaya, Sachiko, Feng, Xingmin, Rios, Olga, DiFebo, Holly, Alemu, Lemlem, Raffo, Diego Quinones, Groarke, Emma M., Flegel, Willy A., Young, Neal S.

“…▪ Clonal hematopoiesis associated with loss of HLA class I alleles due to somatic mutations and/or 6p loss of heterozygosity (LOH) is frequent in immune…”
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High throughput HLA sequence-based typing (SBT) utilizing the ABI Prism 3700 DNA Analyzer by Adams, S D, Barracchini, K C, Simonis, T B, Stroncek, D, Marincola, F M

“…The genetic complexity of the human major histocompatibility complex (MHC) has required the development of various molecular typing methods. The purpose of…”
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The Impact of Cigarette Smoking on the Clinical and Serological Phenotypes of Polymyositis and Dermatomyositis by Schiffenbauer, Adam, Faghihi-Kashani, Sara, O’Hanlon, Terrence P., Flegel, Willy A., Adams, Sharon D., Targoff, Ira N., Oddis, Chester V., Ytterberg, Steven R., Aggarwal, Rohit, Christopher-Stine, Lisa, Shamim, Ejaz A., Dellaripa, Paul F., Danoff, Sonye K., Mammen, Andrew, Miller, Frederick W.

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P064 : KIR mRNA EXPRESSION IN NATURAL KILLER CELLS AND PERIPHERAL BLOOD MONONUCLEAR CELLS ASSAYED BY QUANTITATIVE REAL-TIME PCR by Yuan, Yao, Adams, Sharon D., Dinauer, David M., Rosenau, Christopher M., Uribe, Marcela R., Flegel, Willy A.

“…To develop assays to quantify the mRNA transcribed from 15 KIR functional genes utilizing a quantitative real-time PCR (qPCR) method. To study the KIR mRNA…”
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