Search Results - "Adams, Melissa D"
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Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae Cause Dependence on the Hir/Hpc Pathway: Polymerase Passage May Degrade Chromatin Structure
Published in Genetics (Austin) (01-12-2002)“…Spt16/Cdc68, Pob3, and Nhp6 collaborate in vitro and in vivo as the yeast factor SPN, which is homologous to human FACT. SPN/FACT complexes mediate passage of…”
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Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion
Published in Proceedings of the National Academy of Sciences - PNAS (02-11-2004)“…Bloom syndrome is a rare disorder associated with cancer predisposition and genomic instability and is caused by loss of the RecQ helicase BLM. The Drosophila…”
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The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90
Published in PloS one (10-06-2009)“…A hallmark of AIDS progression is a switch of cytokines from Th1 to Th2 in the plasma of patients. IL-12, a critical Th1 cytokine secreted by antigen…”
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Modulation of P-Element Pre-mRNA Splicing by a Direct Interaction between PSI and U1 snRNP 70K Protein
Published in Molecular cell (01-08-2001)“…P-element somatic inhibitor (PSI) is a KH domain-containing splicing factor highly expressed in Drosophila somatic tissues. Here we have identified a direct…”
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Biochemistry and regulation of pre-mRNA splicing
Published in Current opinion in cell biology (01-06-1996)“…During the past year, significant advances have been made in the field of pre-mRNA splicing. It is now clear that members of the serine—arginine-rich protein…”
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Drosophila BLM in Double-Strand Break Repair by Synthesis-Dependent Strand Annealing
Published in Science (American Association for the Advancement of Science) (10-01-2003)“…Bloom syndrome, characterized by a predisposition to cancer, is caused by mutation of the RecQ DNA helicase gene BLM. The precise function of BLM remains…”
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From sequence to phenotype: reverse genetics in drosophila melanogaster
Published in Nature reviews. Genetics (01-03-2002)“…There has been a long history of innovation and development of tools for gene discovery and genetic analysis in Drosophila melanogaster. This includes methods…”
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Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion
Published in BMC molecular biology (17-10-2008)“…RNA transfection into dendritic cells (DCs) is widely used to achieve antigen expression as well as to modify DC properties. CD40L is expressed by activated T…”
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Comparative Effects of Englitazone and Glyburide on Gluconeogenesis and Glycolysis in the Isolated Perfused Rat Liver
Published in Biochemical pharmacology (01-06-1998)“…Englitazone (CP 68,722, Pfizer) is a member of a family of drugs known as thiazolidinediones. One member of this family, troglitazone (Rezulin), is currently…”
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Isolation of RNA from cell lines and cervical cytology specimens stored in BD SurePath™ preservative fluid and downstream detection of housekeeping gene and HPV E6 expression using real time RT-PCR
Published in Journal of virological methods (01-03-2009)“…This study was performed to demonstrate that RNA isolated from cell lines and cervical cytology specimens stored in SurePath™ preservative fluid would be…”
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The KH-type RNA-binding protein PSI is required for Drosophila viability, male fertility, and cellular mRNA processing
Published in Genes & development (01-01-2002)“…Direct interactions between RNA-binding proteins and snRNP particles modulate eukaryotic pre-mRNA processing patterns to control gene expression. Here, we…”
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An in vitro-selected RNA-binding site for the KH domain protein PSI acts as a splicing inhibitor element
Published in RNA (Cambridge) (01-09-2001)“…P element somatic inhibitor (PSI) is a 97-kDa RNA-binding protein with four KH motifs that is involved in the inhibition of splicing of the Drosophila P…”
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RNA Binding Activity of Heterodimeric Splicing Factor U2AF: at Least One RS Domain Is Required for High-Affinity Binding
Published in Molecular and Cellular Biology (01-07-1998)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Unconventional Processing of the 3' Termini of the Epstein-Barr Virus DNA Polymerase mRNA
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-1993)“…Northern blot analysis of the Epstein-Barr virus DNA polymerase mRNA identified two discrete sizes of virally encoded polymerase transcripts, 5.08 kb detected…”
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Abstract 4620: The Secretory Leukocyte Peptidase Inhibitor (SLPI) is differentially expressed in normal ovary and ovarian tumor tissues
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Background: The prognosis for epithelial ovarian cancer (EOC) is significantly improved if detected and treated while contained in the ovaries…”
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Abstract 2739: Claudin-3 expression is up-regulated in epithelial ovarian cancer tissues, including tumors with minimally elevated levels of CA125
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Background: Epithelial ovarian cancer (EOC) is a leading cause of death from gynecological malignancies in the US. The high mortality rate associated…”
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Isolation of RNA from residual BD SurePath™ liquid-based cytology specimens and detection of HPV E6/E7 mRNA using the PreTect™ HPV-Proofer assay
Published in Journal of virological methods (01-12-2008)“…Infection with high-risk human papillomavirus (HPV) is known to be associated directly with the development of cervical cancer. Recent data suggests that the…”
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Isolation of RNA from residual BD SurePath liquid-based cytology specimens and detection of HPV E6/E7 mRNA using the PreTectt HPV-Proofer assay
Published in Journal of virological methods (01-12-2008)“…Infection with high-risk human papillomavirus (HPV) is known to be associated directly with the development of cervical cancer. Recent data suggests that the…”
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The alternative splicing factor PSI regulates P-element third intron splicing in vivo
Published in Genes & development (01-01-1997)“…Splicing of the Drosophila P-element third intron (IVS3) is inhibited in somatic cells, restricting transposase expression to the germ line. Somatic inhibition…”
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