Assessing the Impact of Migraine on Health-Related Quality of Life: An Additional Use of the Quality of Well-being Scale-Self-administered

Objectives.—To compare the interviewer‐administered Quality of Well‐being Scale (QWB) with a self‐administered form (QWB‐SA) for patients with migraine, and to compare the health status of migraineurs to other medical populations. Background.—With the increasing need to document the cost‐effectivene...

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Bibliographic Details
Published in:	Headache Vol. 40; no. 8; pp. 662 - 671
Main Authors:	Sieber, William J., David, Kristin M., Adams, Jim E., Kaplan, Robert M., Ganiats, Theodore G.
Format:	Journal Article
Language:	English
Published:	Boston, MA, USA Blackwell Science Inc 01-09-2000 Blackwell Wiley Subscription Services, Inc
Subjects:	Adult Biological and medical sciences cost-effectiveness Female Health Status health-related quality of life Humans Interviews as Topic Male Medical sciences Middle Aged migraine Migraine Disorders - physiopathology Neurology Quality of Life QWB-SA Self Administration Sickness Impact Profile Vascular diseases and vascular malformations of the nervous system Human Nervous system diseases Prognosis Self evaluation Migraine Cardiovascular disease Cerebral disorder Quality of life Vascular disease Disability Pain Treatment Central nervous system disease Cerebrovascular disease
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Summary:	Objectives.—To compare the interviewer‐administered Quality of Well‐being Scale (QWB) with a self‐administered form (QWB‐SA) for patients with migraine, and to compare the health status of migraineurs to other medical populations. Background.—With the increasing need to document the cost‐effectiveness of treatment for migraine, limitations with both the Medical Outcomes Study Short Form‐36 items and the QWB have been an impediment to research using cost‐effectiveness as an outcome. Demonstrating the sensitivity of an alternative instrument which addresses these limitations would facilitate cost‐effectiveness analyses on treatments for migraine. Methods.—Eighty‐nine adults (87% women) known to suffer from migraine were asked to complete both the interviewer‐administered QWB and the self‐administered version (QWB‐SA) on three occasions. The first occasion was on a day when no migraine was experienced in the previous 7 days. The second and third assessments were completed within 48 hours of the onset of a migraine. Results.—While both the QWB and the QWB‐SA successfully distinguished migraine from nonmigraine days, more migraines were reported on the QWB‐SA. Overall, both instruments showed similar patterns of patient dysfunction during a migraine attack. Each component of the QWB‐SA successfully distinguished migraine from nonmigraine days, and the QWB‐SA showed a linear sensitivity to pain intensity and disability during a migraine episode. Both instruments are able to detect a migraine's effect on multiple domains of quality of life. Study participants scored significantly lower on the QWB‐SA during a migraine episode than several comparison medical populations. Conclusions.—The QWB and the QWB‐SA appear to have sensitivity to migraine severity, and the ability to quantitate an effect in multiple quality‐of‐life domains. Both measures can be used to calculate quality‐adjusted life‐years, thus facilitating cost‐effectiveness and health policy work in this important clinical area.
Bibliography:	istex:DC721BE0C6B7D20536A00DEF258DDE1D648AE743 ark:/67375/WNG-6R86SD32-W ArticleID:HEAD40008662 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0017-8748 1526-4610
DOI:	10.1046/j.1526-4610.2000.040008662.x