Search Results - "Adams, Jeffrey K."

A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia by Paugh, Steven W., Paugh, Barbara S., Rahmani, Mohamed, Kapitonov, Dmitri, Almenara, Jorge A., Kordula, Tomasz, Milstien, Sheldon, Adams, Jeffrey K., Zipkin, Robert E., Grant, Steven, Spiegel, Sarah

“…The potent bioactive sphingolipid mediator, sphingosine-1-phosphate (S1P), is produced by 2 sphingosine kinase isoenzymes, SphK1 and SphK2. Expression of SphK1…”
Get full text

Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts by KAPITONOV, Dmitri, ALLEGOOD, Jeremy C, SPIEGEL, Sarah, MITCHELL, Clint, HAIT, Nitai C, ALMENARA, Jorge A, ADAMS, Jeffrey K, ZIPKIN, Robert E, DENT, Paul, KORDULA, Tomasz, MILSTIEN, Sheldon

“…Sphingosine-1-phosphate is a potent sphingolipid mediator of diverse processes important for brain tumors, including cell growth, survival, migration,…”
Get full text

Potential anti-inflammatory actions of the elmiric (lipoamino) acids by Burstein, Sumner H., Adams, Jeffrey K., Bradshaw, Heather B., Fraioli, Cristian, Rossetti, Ronald G., Salmonsen, Rebecca A., Shaw, John W., Walker, J. Michael, Zipkin, Robert E., Zurier, Robert B.

“…A library of amino acid-fatty acid conjugates (elmiric acids) was synthesized and tested for their possible use as anti-inflammatory agents. The compounds were…”
Get full text

The Future of Robotic Design: Trends From the History of Media Representations by Schaefer, Kristin E., Adams, Jeffrey K., Cook, Jacquelyn G., Bardwell-Owens, Angela, Hancock, Peter A.

“…The perception of what constitutes a robot depends on both technological advances and evolving social perceptions. Here, we explore how the fictional media…”
Get full text

Design and synthesis of compounds that extend yeast replicative lifespan by Yang, Hongying, Baur, Joseph A., Chen, Allen, Miller, Christine, Sinclair, David A.

“…Summary This past decade has seen the identification of numerous conserved genes that extend lifespan in diverse species, yet the number of compounds that…”
Get full text

Clearance of Aggresome‐Like Inclusion Bodies from SK‐N‐SH Human Neuroblastoma Cells through Increasing Autophagic Flux by Patton, Wayne Forrest, Shen, Dee, Adams, Jeffrey K., Sheppard, Paul W.

“…Pathological inclusion bodies containing aggregated proteins are characteristic of various neurodegenerative diseases, including Parkinson's, Alzheimer's and…”
Get full text

Augmented Emotion and its Remote Embodiment: The Importance of Design from Fiction to Reality by Schaefer, Kristin E., Cook, Jacquelyn G., Adams, Jeffrey K., Bell, Jonathan, Sanders, Tracy L., Hancock, P. A.

“…In this work, we address the under-emphasized need for attention to the emotional dynamics involved in human-robot interaction. This becomes more prominent as…”
Get full text

Syntheses and photophysical properties of some 5(2)-aryl-2(5)-(4-pyridyl)oxazoles and related oxadiazoles and furans by Herbert Hall, J., Chien, Joseph Yuming, Kauffman, Joel M., Litak, Peter T., Adams, Jeffrey K., Henry, Ronald A., Hollins, Richard A.

“…A number of 5‐aryl‐2‐(4‐pyridyl)oxazoles, a 2‐aryl‐5‐(4‐pyridyl)oxazole, the related oxadiazole and furan, several 2‐(4‐pyridyl)cycloalkano[d]oxazoles, and…”
Get full text