Search Results - "Adamo, Ana M"
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Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis
Published in Redox biology (01-09-2019)“…The gastrointestinal (GI) tract can play a critical role in the development of pathologies associated with overeating, overweight and obesity. We previously…”
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(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance
Published in Redox biology (01-04-2018)“…Increased permeability of the intestinal barrier is proposed as an underlying factor for obesity-associated pathologies. Consumption of high fat diets (HFD) is…”
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Early Developmental Marginal Zinc Deficiency Affects Neurogenesis Decreasing Neuronal Number and Altering Neuronal Specification in the Adult Rat Brain
Published in Frontiers in cellular neuroscience (01-03-2019)“…During pregnancy, a decreased availability of zinc to the fetus can disrupt the development of the central nervous system leading to defects ranging from…”
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Hexameric procyanidins inhibit colorectal cancer cell growth through both redox and non-redox regulation of the epidermal growth factor signaling pathway
Published in Redox biology (01-01-2021)“…Dietary proanthocyanidins (PAC) consumption is associated with a decreased risk for colorectal cancer (CRC). Dysregulation of the epidermal growth factor (EGF)…”
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Zinc deficiency and neurodevelopment: The case of neurons
Published in BioFactors (Oxford) (01-03-2010)“…Zinc is essential for normal brain development. Gestational severe zinc deficiency can lead to overt fetal brain malformations. Although not teratogenic,…”
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Gestational zinc deficiency impairs brain astrogliogenesis in rats through multistep alterations of the JAK/STAT3 signaling pathway
Published in Redox biology (01-08-2021)“…We previously showed that zinc (Zn) deficiency affects the STAT3 signaling pathway in part through redox-regulated mechanisms. Given that STAT3 is central to…”
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The Role of Zinc in the Modulation of Neuronal Proliferation and Apoptosis
Published in Neurotoxicity research (01-01-2010)“…Although a requirement of zinc (Zn) for normal brain development is well documented, the extent to which Zn can modulate neuronal proliferation and apoptosis…”
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Di-2-ethylhexyl phthalate affects zinc metabolism and neurogenesis in the developing rat brain
Published in Archives of biochemistry and biophysics (30-09-2022)Get full text
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Oligodeoxynucleotide IMT504: Effects on Central Nervous System Repair Following Demyelination
Published in Molecular neurobiology (01-07-2024)“…Multiple sclerosis (MS) is an immune-mediated central nervous system (CNS) disease characterized by demyelination resulting from oligodendrocyte loss and…”
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Sphingolipid Metabolism Is a Crucial Determinant of Cellular Fate in Nonstimulated Proliferating Madin-Darby Canine Kidney (MDCK) Cells
Published in The Journal of biological chemistry (12-09-2008)“…The present report was addressed to study the influence of sphingolipid metabolism in determining cellular fate. In nonstimulated proliferating Madin-Darby…”
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Nutritional factors and aging in demyelinating diseases
Published in Genes & nutrition (01-01-2014)“…Demyelination is a pathological process characterized by the loss of myelin around axons. In the central nervous system, oligodendroglial damage and…”
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Demyelination-remyelination in the Central Nervous System: Ligand-dependent Participation of the Notch Signaling Pathway
Published in Toxicological sciences (01-09-2019)“…Multiple sclerosis (MS) is an immune-mediated central nervous system disease mostly affecting young people. Multiple sclerosis and other neurodegenerative and…”
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(−)-Epicatechin reduces blood pressure increase in high-fructose-fed rats: effects on the determinants of nitric oxide bioavailability
Published in The Journal of nutritional biochemistry (01-07-2015)“…This work investigated the blood pressure (BP)-lowering effect of the flavanol (−)-epicatechin in a model of metabolic syndrome. Rats were fed a regular chow…”
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Curcumin induces cell‐arrest and apoptosis in association with the inhibition of constitutively active NF‐κB and STAT3 pathways in Hodgkin's lymphoma cells
Published in International journal of cancer (01-07-2008)“…Although treatment of Hodgkin's lymphoma (HL) with a multi‐drug approach has been very successful, its toxicity becomes evident after several years as…”
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TGF‐β pro‐oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway
Published in Glia (01-02-2018)“…Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming…”
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Blood pressure-lowering effect of dietary (−)-epicatechin administration in L-NAME-treated rats is associated with restored nitric oxide levels
Published in Free radical biology & medicine (15-11-2012)“…Epidemiological and intervention studies have shown that the intake of certain chocolates or cocoa products decreases blood pressure (BP) in humans…”
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Gestational marginal zinc deficiency impaired fetal neural progenitor cell proliferation by disrupting the ERK1/2 signaling pathway
Published in The Journal of nutritional biochemistry (01-11-2015)“…This study investigated if a marginal zinc deficiency during gestation in rats could affect fetal neural progenitor cell (NPC) proliferation through a…”
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Presenilin 1 overexpressions in Chinese hamster ovary (CHO) cells decreases the phosphorylation of retinoblastoma protein: relevance for neurodegeneration
Published in Neuroscience letters (21-06-2002)“…Mutations in the presenilin 1 (PS1) gene have been associated to familial Alzheimer disease although the exact pathogenic mechanism is unclear. We report that…”
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TGF-[beta] pro-oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway
Published in Glia (01-02-2018)“…Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming…”
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