Search Results - "Adamkova, V"

A haemochromatosis-causing HFE mutation is associated with SARS-CoV-2 susceptibility in the Czech population by Hubacek, J.A., Philipp, T., Adamkova, V., Majek, O., Dusek, L.

“…•Severe acute respiratory syndrome coronavirus 2 rapidly spread to all continents.•Increased plasma levels of Fe have the potential to affect infection…”
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SARS-CoV-2 viral load is linked to remdesivir efficacy in severe Covid-19 admitted to intensive care by Balik, M., Waldauf, P., Jurisinova, I., Svobodova, E., Diblickova, M., Tencer, T., Zavora, J., Smela, G., Kupidlovska, L., Adamkova, V., Fridrichova, M., Jerabkova, K., Mikes, J., Duska, F., Dusek, L.

“…Remdesivir therapy has been declared as efficient in the early stages of Covid-19. Of the 339 patients (males 55.8%, age 71(59;77) years) with a detectable…”
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Relation of central and brachial blood pressure to left ventricular hypertrophy. The Czech Post-MONICA Study by Wohlfahrt, P, Wichterle, D, Seidlerová, J, Filipovský, J, Bruthans, J, Adámková, V, Cífková, R

“…Central blood pressure (BP) has been shown to be a better predictor of target organ damage and cardiovascular events than brachial BP. Whether central BP is a…”
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Polygenic hypercholesterolemia: examples of GWAS results and their replication in the Czech-Slavonic population by Hubacek, J A, Adamkova, V, Lanska, V, Dlouha, D

“…Since 2007, the year of their first widespread use, genome-wide association studies (GWAS) have become the "gold standard" for the detection of causal genes…”
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Statin-associated myopathy: from genetic predisposition to clinical management by Vrablik, M, Zlatohlavek, L, Stulc, T, Adamkova, V, Prusikova, M, Schwarzova, L, Hubacek, J A, Ceska, R

“…Statin-associated myopathy (SAM) represents a broad spectrum of disorders from insignificant myalgia to fatal rhabdomyolysis. Its frequency ranges from 1-5 %…”
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Carriers of the LDL receptor mutations within the exon 12 in general population by Hubacek, J, Fellnerova, A, Dlouha, D, Schwarzova, L, Adamkova, V

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Rs6922269 marker at the MTHFD1L gene predict cardiovascular mortality in males after acute coronary syndrome by Hubacek, J, Stanek, V, Poledne, R, Adamkova, V, Pitha, J

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SNPs within CHRNA5-A3-B4 and CYP2A6/B6 are associated with smoking dependence but not with tobacco dependence treatment outcomes in the Czech population by Hubacek, J.A., Pankova, A., Stepankova, L., Zvolska, K., Adamkova, V., Lanska, V., Kralikova, E.

“…Tobacco/nicotine dependence has a significant heritable component. Genome-wide association studies have associated the single nucleotide polymorphisms (SNPs)…”
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30-YEAR TRENDS IN BLOOD PRESSURE, PREVALENCE, AWARENESS, TREATMENT AND CONTROL OF HYPERTENSION IN THE CZECH REPUBLIC. THE CZECH MONICA AND CZECH POST-MONICA STUDIES by Cifkova, R, Bruthans, J, Wohlfahrt, P, Krajcoviechova, A, Sulc, P, Lanska, V, Jozifova, M, Filipovsky, J, Mayer, O, Linhart, A, Widimsky, J, Adamkova, V, Hovorkova, M, Skodova, Z

“…OBJECTIVE:Unlike most former East Bloc countries, the Czech Republic has seen a decrease in total, and cardiovascular (CV) mortality; the decrease, since 1985,…”
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Association between marker at chromosome 2 and acute coronary syndrome is modified by statins by Hubacek, J.A, Adamkova, V, Stanek, V, Pitha, J

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The risk factors of atherosclerosis in roma population in south bohemia by Adamkova, V, Hubacek, J, Novakova, D, Adamek, V, Lanska, V, Tothova, V

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Genetic Markers at ANRIL, FTO and 2q36.3 Locus in Czech Patients Undergoing Coronary Artery Bypass Graft Surgery by Kacer, P, Pirk, J, Lanska, V, Hubacek, J A, Adamek, V, Cervinkova, T, Belohoubek, J, Auzky, O, Adamkova, V

“…Coronary artery bypass graft (CABG) surgery is one of the most commonly performed operations worldwide. We compared genotype frequencies of three major…”
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Gene variants at FTO, 9p21, and 2q36.3 are age-independently associated with myocardial infarction in Czech men by Hubacek, J.A., Vrablik, M., Dlouha, D., Stanek, V., Gebauerova, M., Adamkova, V., Ceska, R., Dostálová, G., Linhart, A., Vitek, L., Pitha, J.

“…Cardiovascular disease (CVD) is a major cause of morbidity and mortality in developed countries. This study aimed to confirm the effect of common putative…”
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Rs6922269 marker at the MTHFD1L gene predict cardiovascular mortality in males after acute coronary syndrome by Hubacek, J. A., Staněk, V., Gebauerová, M., Poledne, R., Aschermann, M., Skalická, H., Matoušková, J., Kruger, A., Pěnička, M., Hrabáková, H., Veselka, J., Hájek, P., Lánská, V., Adámková, V., Piťha, J.

“…Myocardial infarction (MI) is the leading cause of death in industrialized countries. All the traditional risk factors for MI are responsible for approximately…”
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Traditional risk factors of acute coronary syndrome in four different male populations - total cholesterol value does not seem to be relevant risk factor by Hubacek, J A, Stanek, V, Gebauerova, M, Adamkova, V, Lesauskaite, V, Zaliaduonyte-Peksiene, D, Tamosiunas, A, Supiyev, A, Kossumov, A, Zhumadilova, A, Pitha, J

“…Cardiovascular diseases are the most common cause of mortality and morbidity in most populations. As the traditional modifiable risk factors (smoking,…”
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SLCO1B1 transporter polymorphism is not associated with risk of myopathy in Czech population by Hubacek, J.A, Dlouha, D, Adamkova, V, Ceska, R, Vrablik, M

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The effect of colesevelam treatment on bile acid and lipid metabolism and glycemic control in healthy men by Blahová, T, Peterková, L, Leníček, M, Vlachová, M, Zemánková, K, Adámková, V, Vítek, L, Kovář, J

“…The treatment of hypercholesterolemia with bile acid (BA) sequestrants results in upregulation of BA synthesis through the classical pathway initiated by…”
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Strong gender-specific additive effects of the NYD-SP18 and FTO variants on BMI values by Hubacek, J A, Dlouha, D, Lanska, V, Adamkova, V

“…The role of the FTO gene in obesity development is well established in populations around the world. The NYD-SP18 variant has been suggested to have a similar…”
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Strong Association between APOA5 Gene Polymorphisms and Hypertriglyceridaemic Episodes by Vrablik, M, Hubacek, J A, Dlouha, D, Satny, M, Adamkova, V, Ceska, R

“…Plasma triglyceride (TG) levels represent a significant risk factor of cardiovascular and total mortality. Concentrations of TG in the plasma depend, to a…”
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Large copy-number variations in patients with statin-associated myopathy affecting statin myopathy-related loci by Stránecký, V, Neřoldová, M, Hodaňová, K, Hartmannová, H, Piherová, L, Zemánková, P, Přistoupilová, A, Vrablík, M, Adámková, V, Kmoch, S, Jirsa, M

“…Some patients are susceptible to statin-associated myopathy (SAM) either because of genetic variations affecting statin uptake and metabolism, or because they…”
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