Search Results - "Adamala, Katarzyna"

A simple physical mechanism enables homeostasis in primitive cells by Engelhart, Aaron E., Adamala, Katarzyna P., Szostak, Jack W.

“…The emergence of homeostatic mechanisms that enable maintenance of an intracellular steady state during growth was critical to the advent of cellular life…”
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Laws of thought in living cells by Sorenson, Carlise, Adamala, Katarzyna P

“…Building biological computers is one of the most intensively pursued goals of modern synthetic biology. The new TriLoS tristate-based logic synthesis platform,…”
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Nonenzymatic Template-Directed RNA Synthesis Inside Model Protocells by Adamala, Katarzyna, Szostak, Jack W.

“…Efforts to recreate a prebiotically plausible protocell, in which RNA replication occurs within a fatty acid vesicle, have been stalled by the destabilizing…”
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Competition between model protocells driven by an encapsulated catalyst by Adamala, Katarzyna, Szostak, Jack W.

“…The advent of Darwinian evolution required the emergence of molecular mechanisms for the heritable variation of fitness. One model for such a system involves…”
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Engineering genetic circuit interactions within and between synthetic minimal cells by Adamala, Katarzyna P., Martin-Alarcon, Daniel A., Guthrie-Honea, Katriona R., Boyden, Edward S.

“…Genetic circuits and reaction cascades are of great importance for synthetic biology, biochemistry and bioengineering. An open question is how to maximize the…”
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Toward synthetic life: Biomimetic synthetic cell communication by Robinson, Abbey O., Venero, Orion M., Adamala, Katarzyna P.

“…Engineering synthetic minimal cells provide a controllable chassis for studying the biochemical principles of natural life, increasing our understanding of…”
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Synthetic cells in biomedical applications by Sato, Wakana, Zajkowski, Tomasz, Moser, Felix, Adamala, Katarzyna P.

“…Synthetic cells are engineered vesicles that can mimic one or more salient features of life. These features include directed localization, sense‐and‐respond…”
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Collaboration between primitive cell membranes and soluble catalysts by Adamala, Katarzyna P., Engelhart, Aaron E., Szostak, Jack W.

“…One widely held model of early life suggests primitive cells consisted of simple RNA-based catalysts within lipid compartments. One possible selective…”
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Reconstituting Natural Cell Elements in Synthetic Cells by Gaut, Nathaniel J., Adamala, Katarzyna P.

“…Building a live cell from non‐living building blocks would be a fundamental breakthrough in biological sciences, and it would enable engineering new lineages…”
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Toward artificial photosynthesis by Gaut, Nathaniel J, Adamala, Katarzyna P

“…Microfluidics lights the way to a synthetic plant-like cell The creation of a fully artificial living cell would signify progress in both understanding current…”
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Present and future of synthetic cell development by Adamala, Katarzyna P., Dogterom, Marileen, Elani, Yuval, Schwille, Petra, Takinoue, Masahiro, Tang, T-Y Dora

“…Scientists are captivated by the prospect of creating a fully synthetic cell, offering the potential to revolutionize biology, medicine and biotechnology. In…”
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PACRAT: pathogen detection with aptamer-observed cascaded recombinase polymerase amplification-in vitro transcription by Khan, Pavana, Aufdembrink, Lauren M, Adamala, Katarzyna P, Engelhart, Aaron E

“…The SARS-CoV-2 pandemic underscored the need for early, rapid, and widespread pathogen detection tests that are readily accessible. Many existing rapid…”
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Akaby-Cell-free protein expression system for linear templates by Sato, Wakana, Sharon, Judee, Deich, Christopher, Gaut, Nathaniel, Cash, Brock, Engelhart, Aaron E, Adamala, Katarzyna P

“…Cell-free protein expression is increasingly becoming popular for biotechnology, biomedical and research applications. Among cell-free systems, the most…”
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Expanding luciferase reporter systems for cell-free protein expression by Sato, Wakana, Rasmussen, Melanie, Deich, Christopher, Engelhart, Aaron E., Adamala, Katarzyna P.

“…Luciferases are often used as a sensitive, versatile reporter in cell-free transcription-translation (TXTL) systems, for research and practical applications…”
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Programmable RNA-binding protein composed of repeats of a single modular unit by Adamala, Katarzyna P., Martin-Alarcon, Daniel A., Boyden, Edward S.

“…The ability to monitor and perturb RNAs in living cells would benefit greatly from a modular protein architecture that targets unmodified RNA sequences in a…”
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Diffusion control in biochemical specificity by Alejo, Jose L., Kempes, Christopher P., Adamala, Katarzyna P.

“…Biochemical specificity is critical in enzyme function, evolution, and engineering. Here we employ an established kinetic model to dissect the effects of…”
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Rapid deployment of smartphone‐based augmented reality tools for field and online education in structural biology by Sung, Rou‐Jia, Adamala, Katarzyna Z., Engelhart, Aaron E.

“…Structural biology education commonly employs molecular visualization soft‐ ware, such as PyMol, RasMol, and VMD, to allow students to appreciate…”
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Emergent ribozyme behaviors in oxychlorine brines indicate a unique niche for molecular evolution on Mars by Hoog, Tanner G., Pawlak, Matthew R., Gaut, Nathaniel J., Baxter, Gloria C., Bethel, Thomas A., Adamala, Katarzyna P., Engelhart, Aaron E.

“…Mars is a particularly attractive candidate among known astronomical objects to potentially host life. Results from space exploration missions have provided…”
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A gene expression control technology for cell‐free systems and synthetic cells via targeted gene silencing and transfection by Sato, Wakana, Rasmussen, Melanie, Gaut, Nathaniel, Devarajan, Mahima, Stokes, Kaitlin, Deich, Christopher, Engelhart, Aaron E., Adamala, Katarzyna P.

“…Synthetic cells, expressing proteins using cell‐free transcription‐translation (TXTL), is a technology utilized for a variety of applications, such as…”
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Preparing for the future of precision medicine: synthetic cell drug regulation by Sampson, Kira, Sorenson, Carlise, Adamala, Katarzyna P

“…Abstract Synthetic cells are a novel class of cell-like bioreactors, offering the potential for unique advancements in synthetic biology and biomedicine. To…”
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