Search Results - "Adam, Sylvain Marchand"

Determinants of survival after lung transplantation in telomerase‐related gene mutation carriers: A retrospective cohort by Phillips‐Houlbracq, Mathilde, Mal, Hervé, Cottin, Vincent, Gauvain, Clément, Beier, Fabian, Sicre de Fontbrune, Flore, Sidali, Sabrina, Mornex, Jean François, Hirschi, Sandrine, Roux, Antoine, Weisenburger, Gaelle, Roussel, Arnaud, Wémeau‐Stervinou, Lidwine, Le Pavec, Jérôme, Pison, Christophe, Marchand Adam, Sylvain, Froidure, Antoine, Lazor, Romain, Naccache, Jean‐Marc, Jouneau, Stéphane, Nunes, Hilario, Reynaud‐Gaubert, Martine, Le Borgne, Aurélie, Boutboul, David, Ba, Ibrahima, Boileau, Catherine, Crestani, Bruno, Kannengiesser, Caroline, Borie, Raphaël

“…Carriers of germline telomerase‐related gene (TRG) mutations can show poor prognosis, with an increase in common hematological complications after lung…”
Get full text

Inhibition of the Arp2/3 complex represses human lung myofibroblast differentiation and attenuates bleomycin‐induced pulmonary fibrosis by Mergault, Coralie, Lisée, Fanny, Tiroille, Victor, Magnien, Mélia, Parent, Christelle, Lenga Mabonda, Woodys, Sizaret, Damien, Jaillet, Madeleine, Crestani, Bruno, Marchand‐Adam, Sylvain, Plantier, Laurent

“…Background and Purpose The Arp2/3 multiprotein complex regulates branched polymerisation of the actin cytoskeleton and may contribute to collagen synthesis and…”
Get full text

Population pharmacokinetics of mycophenolate in patients treated for interstitial lung disease (EVER‐ILD study) by Xu, Yan‐Min, Ternant, David, Reynaud‐Gaubert, Martine, Bejan‐Angoulvant, Théodora, Marchand‐Adam, Sylvain

“…Background Mycophenolate mofetil (MMF) has been used to treat interstitial lung disease (ILD), but mycophenolate (MPA) pharmacokinetics was not reported for…”
Get full text

Transcutaneous PCO2‐based dead space ventilation at submaximal exercise accurately discriminates healthy controls from patients with chronic obstructive pulmonary disease by Leprat, Thibault, Ivanes, Fabrice, Bernard, Anne, Marchand‐Adam, Sylvain, Plantier, Laurent

“…Background Increased physiological dead space ventilation (VD/VT) at exercise reflects pulmonary gas exchange impairment and is a sensitive marker of…”
Get full text

Impulse oscillometry and spirometry measurements relative to personal best values at the time of acute exacerbations of cystic fibrosis in adults by Blin, Timothée, Flament, Thomas, Mankikian, Julie, Chambellan, Arnaud, Marchand‐Adam, Sylvain, Plantier, Laurent

“…Background Diagnosis of acute exacerbation (AE) of cystic fibrosis (CF) must be precise because both under‐ and over‐prescription of antibiotics may be…”
Get full text

Similarities and differences of interstitial lung disease associated with pathogenic variants in SFTPC and ABCA3 in adults by Diesler, Rémi, Legendre, Marie, Si‐Mohamed, Salim, Brillet, Pierre‐Yves, Wemeau, Lidwine, Manali, Effrosyni D., Gagnadoux, Frédéric, Hirschi, Sandrine, Lorillon, Gwenaël, Reynaud‐Gaubert, Martine, Bironneau, Vanessa, Blanchard, Elodie, Bourdin, Arnaud, Dominique, Stéphane, Justet, Aurélien, Macey, Julie, Marchand‐Adam, Sylvain, Morisse‐Pradier, Hélène, Nunes, Hilario, Papiris, Spyros A., Traclet, Julie, Traore, Ibrahim, Crestani, Bruno, Amselem, Serge, Nathan, Nadia, Borie, Raphaël, Cottin, Vincent, Taam, Rola Abou, Bermudez, Julien, Bonniaud, Philippe, Brudon, Alexandre, Cros, Pierrick, Delestrain, Céline, Epaud, Ralph, Fouquet, Helen, Gondouin, Anne, Duverge, Alice Hadchouel, Jouneau, Stéphane, Juvin, Karine, Le Pavec, Jérôme, Meurice, Jean‐Claude, Nasser, Mouhamad, Pastre, Jean, Picard, Clément, Provost, Mathilde, Tissot, Adrien, Uzunhan, Yurdagul, Valeyre, Dominique

“…Background and Objective Variants in surfactant genes SFTPC or ABCA3 are responsible for interstitial lung disease (ILD) in children and adults, with few…”
Get full text

Comprehensive clinical profiling of the Gauting locoregional lung adenocarcinoma donors by Klotz, Laura V., Courty, Yves, Lindner, Michael, Petit‐Courty, Agnès, Stowasser, Anja, Koch, Ina, Eichhorn, Martin E., Lilis, Ioannis, Morresi‐Hauf, Alicia, Arendt, Kristina A. M., Pepe, Mario, Giopanou, Ioanna, Ntaliarda, Giannoula, Behrend, Sabine J., Oplopoiou, Maria, Gissot, Valérie, Guyetant, Serge, Marchand‐Adam, Sylvain, Behr, Jürgen, Kaiser, Jan‐Christian, Hatz, Rudolf A., Lamort, Anne‐Sophie, Stathopoulos, Georgios T.

“…A comprehensive characterization of lung adenocarcinoma (LADC) clinical features is currently missing. We prospectively evaluated Caucasian patients with…”
Get full text

Pulmonary manifestations of Sjögren's syndrome by Flament, Thomas, Bigot, Adrien, Chaigne, Benjamin, Henique, Helene, Diot, Elisabeth, Marchand-Adam, Sylvain

“…In 9-20% of cases, Sjögren's syndrome is associated with various respiratory symptoms. The most typical manifestations are chronic interstitial lung disease…”
Get full text

Physiology of the lung in idiopathic pulmonary fibrosis by Plantier, Laurent, Cazes, Aurélie, Dinh-Xuan, Anh-Tuan, Bancal, Catherine, Marchand-Adam, Sylvain, Crestani, Bruno

“…The clinical expression of idiopathic pulmonary fibrosis (IPF) is directly related to multiple alterations in lung function. These alterations derive from a…”
Get full text

Extracellular ATP Is a Danger Signal Activating P2X7 Receptor in Lung Inflammation and Fibrosis by RITEAU, Nicolas, GASSE, Pamela, RYFFEL, Bernhard, COUILLIN, Isabelle, FAUCONNIER, Louis, GOMBAULT, Aurélie, COUEGNAT, Marion, FICK, Lizette, KANELLOPOULOS, Jean, QUESNIAUX, Valérie F. J, MARCHAND-ADAM, Sylvain, CRESTANI, Bruno

“…Pulmonary fibrosis is a devastating as yet untreatable disease. We previously investigated the endogenous mediators released on lung injury and showed that…”
Get full text

Comorbidities of COPD by Cavaillès, Arnaud, Brinchault-Rabin, Graziella, Dixmier, Adrien, Goupil, François, Gut-Gobert, Christophe, Marchand-Adam, Sylvain, Meurice, Jean-Claude, Morel, Hugues, Person-Tacnet, Christine, Leroyer, Christophe, Diot, Patrice

“…By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality. Extrapulmonary comorbidities influence the prognosis of patients…”
Get full text

Women and COPD: do we need more evidence? by Gut-Gobert, Christophe, Cavaillès, Arnaud, Dixmier, Adrien, Guillot, Stéphanie, Jouneau, Stéphane, Leroyer, Christophe, Marchand-Adam, Sylvain, Marquette, David, Meurice, Jean-Claude, Desvigne, Nicolas, Morel, Hugues, Person-Tacnet, Christine, Raherison, Chantal

“…The increasingly female face of chronic obstructive pulmonary disease (COPD) prevalence among women has equalled that of men since 2008, due in part to…”
Get full text

Transcutaneous PCO 2 -based dead space ventilation at submaximal exercise accurately discriminates healthy controls from patients with chronic obstructive pulmonary disease by Leprat, Thibault, Ivanes, Fabrice, Bernard, Anne, Marchand-Adam, Sylvain, Plantier, Laurent

“…Increased physiological dead space ventilation (V /V ) at exercise reflects pulmonary gas exchange impairment and is a sensitive marker of cardio-respiratory…”
Get full text

Clinical performance of four immunoassays for antibodies to SARS-CoV-2, including a prospective analysis for the diagnosis of COVID-19 in a real-life routine care setting by Marlet, Julien, Petillon, Camille, Ragot, Emma, Abou El Fattah, Yazid, Guillon, Antoine, Marchand Adam, Sylvain, Lemaignen, Adrien, Bernard, Louis, Desoubeaux, Guillaume, Blasco, Hélène, Barin, Francis, Stefic, Karl, Gaudy-Graffin, Catherine

“…•The sensitivity of evaluated SARS-CoV-2 immunoassays ranged from 95.6% to 97.8%.•The specificity was 92.1% for Euroimmun IgG and ≥ 98.9% for Abbott IgG,…”
Get full text

Tracheal involvement in ulcerative colitis: clinical presentation and potential interest of 2-deoxy-2[18F]fluoro-d-glucose positron emission tomography (18F-FDG PET) for the management by Jouan, Youenn, Venel, Yann, Lioger, Bertrand, du Sorbier, Christophe Monegier, Gaucher, Luc, Marchand-Adam, Sylvain, Diot, Patrice, Diot, Elisabeth

“…Ulcerative colitis (UC) is an inflammatory bowel disease that can on rare occasions affect the respiratory tract. We report the case of a 32-year-old woman…”
Get full text

B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis by François, Antoine, Gombault, Aurélie, Villeret, Bérengère, Alsaleh, Ghada, Fanny, Manoussa, Gasse, Paméla, Adam, Sylvain Marchand, Crestani, Bruno, Sibilia, Jean, Schneider, Pascal, Bahram, Seiamak, Quesniaux, Valérie, Ryffel, Bernhard, Wachsmann, Dominique, Gottenberg, Jacques-Eric, Couillin, Isabelle

“…Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive devastating, yet untreatable fibrotic disease of unknown origin. We investigated the contribution…”
Get full text

Transcriptome of Cultured Lung Fibroblasts in Idiopathic Pulmonary Fibrosis: Meta-Analysis of Publically Available Microarray Datasets Reveals Repression of Inflammation and Immunity Pathways by Plantier, Laurent, Renaud, Hélène, Respaud, Renaud, Marchand-Adam, Sylvain, Crestani, Bruno

“…Heritable profibrotic differentiation of lung fibroblasts is a key mechanism of idiopathic pulmonary fibrosis (IPF). Its mechanisms are yet to be fully…”
Get full text

Proteomic biomarkers for survival in systemic sclerosis-associated pulmonary hypertension by Mismetti, Valentine, Delavenne, Xavier, Montani, David, Bezzeghoud, Souad, Delezay, Olivier, Hodin, Sophie, Launay, David, Marchand-Adam, Sylvain, Nunes, Hilario, Ollier, Edouard, Reynaud-Gaubert, Martine, Pastre, Jean, Traclet, Julie, Quetant, Sébastien, Zeghmar, Sabrina, Bertoletti, Laurent, Cottin, Vincent

“…Background Interstitial lung disease (ILD) and pulmonary hypertension (PH) represent the major causes of mortality in systemic sclerosis (SSc). Patients with…”
Get full text

Chronic interstitial lung disease associated with systemic lupus erythematosus: A multicentric study of 89 cases by Deneuville, Lou, Mageau, Arthur, Debray, Marie Pierre, Sacre, Karim, Costedoat‐Chalumeau, Nathalie, Hachulla, Eric, Uzunhan, Yurdagul, Le Tallec, Erwan, Cadranel, Jacques, Marchand Adam, Sylvain, Montani, David, Rémi‐Jardin, Martine, Reynaud‐Gaubert, Martine, Prevot, Gregoire, Beltramo, Guillaume, Crestani, Bruno, Cottin, Vincent, Borie, Raphael, Ahmad, Kais, Traclet, Julie, Leguen, Pierre, Bravais, Juliette, Nieves, Ana, Audia, Sylvain, Nunes, Hilario

“…Background and Objective Chronic interstitial lung disease (ILD) occurs rarely with systemic lupus erythematosus (SLE) as compared with other connective tissue…”
Get full text

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases by Hamon, Yveline, Legowska, Monika, Hervé, Virginie, Dallet-Choisy, Sandrine, Marchand-Adam, Sylvain, Vanderlynden, Lise, Demonte, Michèle, Williams, Rich, Scott, Christopher J., Si-Tahar, Mustapha, Heuzé-Vourc'h, Nathalie, Lalmanach, Gilles, Jenne, Dieter E., Lesner, Adam, Gauthier, Francis, Korkmaz, Brice

“…The cysteine protease cathepsin C (CatC) activates granule-associated proinflammatory serine proteases in hematopoietic precursor cells. Its early inhibition…”
Get full text