Search Results - "Adam, Sebastian"

Identifying Sex-Specific Risk Factors for Low Bone Mineral Density in Adolescent Runners by Tenforde, Adam Sebastian, Fredericson, Michael, Sayres, Lauren Carter, Cutti, Phil, Sainani, Kristin Lynn

“…Background: Adolescent runners may be at risk for low bone mineral density (BMD) associated with sports participation. Few prior investigations have evaluated…”
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Biosynthesis of Cittilins, Unusual Ribosomally Synthesized and Post-translationally Modified Peptides from Myxococcus xanthus by Hug, Joachim J, Dastbaz, Jan, Adam, Sebastian, Revermann, Ole, Koehnke, Jesko, Krug, Daniel, Müller, Rolf

“…Cittilins are secondary metabolites from myxobacteria comprised of three l-tyrosines and one l-isoleucine forming a bicyclic tetrapeptide scaffold with biaryl…”
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Macroamidine Formation in Bottromycins Is Catalyzed by a Divergent YcaO Enzyme by Franz, Laura, Adam, Sebastian, Santos-Aberturas, Javier, Truman, Andrew W, Koehnke, Jesko

“…The YcaO superfamily of proteins catalyzes the phosphorylation of peptide backbone amide bonds, which leads to the formation of azolines and azoles in…”
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Latest Trends in Biosensing for Microphysiological Organs-on-a-Chip and Body-on-a-Chip Systems by Kratz, Sebastian Rudi Adam, Höll, Gregor, Schuller, Patrick, Ertl, Peter, Rothbauer, Mario

“…Organs-on-chips are considered next generation tools capable of recreating like, physiological-relevant microenvironments needed to cultivate 3D…”
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Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design by Axer, Alexander, Jumde, Ravindra P, Adam, Sebastian, Faust, Andreas, Schäfers, Michael, Fobker, Manfred, Koehnke, Jesko, Hirsch, Anna K H, Gilmour, Ryan

“…Single site OH → F substitution at the termini of maltotetraose leads to significantly improved hydrolytic stability towards α-amylase and α-glucosidase…”
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Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus by Viehrig, Konrad, Surup, Frank, Volz, Carsten, Herrmann, Jennifer, Abou Fayad, Antoine, Adam, Sebastian, Köhnke, Jesko, Trauner, Dirk, Müller, Rolf

“…Secondary metabolome mining efforts in the myxobacterial multiproducer of natural products, Chondromyces crocatus Cm c5, resulted in the isolation and…”
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Fabrication of biomimetic placental barrier structures within a microfluidic device utilizing two-photon polymerization by Mandt, Denise, Gruber, Peter, Markovic, Marica, Tromayer, Maximillian, Rothbauer, Mario, Kratz, Sebastian Rudi Adam, Ali, Syed Faheem, Hoorick, Jasper Van, Holnthoner, Wolfgang, Mühleder, Severin, Dubruel, Peter, Vlierberghe, Sandra Van, Ertl, Peter, Liska, Robert, Ovsianikov, Aleksandr

“…The placenta is a transient organ, essential for development and survival of the unborn fetus. It interfaces the body of the pregnant woman with the unborn…”
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Participation in Ball Sports May Represent a Prehabilitation Strategy to Prevent Future Stress Fractures and Promote Bone Health in Young Athletes by Tenforde, Adam Sebastian, MD, Lynn Sainani, Kristin, PhD, Carter Sayres, Lauren, BA, Milgrom, Charles, MD, Fredericson, Michael, MD

“…Abstract Sports participation has many benefits for the young athlete, including improved bone health. However, a subset of athletes may attain suboptimal bone…”
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Structure and Substrate Recognition of the Bottromycin Maturation Enzyme BotP by Mann, Greg, Huo, Liujie, Adam, Sebastian, Nardone, Brunello, Vendome, Jeremie, Westwood, Nicholas James, Müller, Rolf, Koehnke, Jesko

“…The bottromycins are a family of highly modified peptide natural products, which display potent antimicrobial activity against Gram‐positive bacteria,…”
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FINCA syndrome—Defining neurobehavioral phenotype in survivors into late childhood by Badura‐Stronka, Magdalena, Śmigiel, Robert, Rutkowska, Karolina, Szymańska, Krystyna, Hirschfeld, Adam Sebastian, Monkiewicz, Michał, Kosińska, Joanna, Wolańska, Ewelina, Rydzanicz, Małgorzata, Latos‐Bieleńska, Anna, Płoski, Rafał

“…Background By 2021, 10 cases of fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA, MIM #618278) syndrome have been reported, and five causative…”
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The Mexican Drug War and the Consequent Population Exodus: Transnational Movement at the U.S.-Mexican Border by Morales, Maria, Morales, Oscar, Menchaca, Angelica, Sebastian, Adam

“…At the frontline of México’s “war on drugs” is the Mexican-U.S. border city of Cd. Juárez, Chihuahua, which has become internationally known as the “murder…”
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Combinatorial in Vitro and in Silico Approach To Describe Shear-Force Dependent Uptake of Nanoparticles in Microfluidic Vascular Models by Charwat, Verena, Olmos Calvo, Isabel, Rothbauer, Mario, Kratz, Sebastian Rudi Adam, Jungreuthmayer, Christian, Zanghellini, Jürgen, Grillari, Johannes, Ertl, Peter

“…In the present work, we combine experimental and computational methods to define the critical shear stress as an alternative parameter for nanotoxicological…”
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Optimized alamarBlue assay protocol for drug dose-response determination of 3D tumor spheroids by Eilenberger, Christoph, Kratz, Sebastian Rudi Adam, Rothbauer, Mario, Ehmoser, Eva-Kathrin, Ertl, Peter, Küpcü, Seta

“…[Display omitted] The assessment of drug-dose responses is vital for the prediction of unwanted toxicological effects in modern medicine. Three-dimensional…”
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Thioholgamides: Thioamide-Containing Cytotoxic RiPP Natural Products by Kjaerulff, Louise, Sikandar, Asfandyar, Zaburannyi, Nestor, Adam, Sebastian, Herrmann, Jennifer, Koehnke, Jesko, Müller, Rolf

“…Thioviridamide is a structurally unique ribosomally synthesized and post-translationally modified peptide that contains several thioamide bonds and is active…”
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1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding by Hamid, Rawia, Adam, Sebastian, Lacour, Antoine, Monjas, Leticia, Köhnke, Jesko, Hirsch, Anna K.H.

“…The ESKAPE bacteria are the six highly virulent and antibiotic-resistant pathogens that require the most urgent attention for the development of novel…”
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Characterization of the Stereoselective P450 Enzyme BotCYP Enables the In Vitro Biosynthesis of the Bottromycin Core Scaffold by Adam, Sebastian, Franz, Laura, Milhim, Mohammed, Bernhardt, Rita, Kalinina, Olga V, Koehnke, Jesko

“…Bottromycins are ribosomally synthesized and post-translationally modified peptide natural product antibiotics that are effective against high-priority human…”
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Autoimmune mediated hyperkinetic movement disorders in SARS-CoV-2 infection - a systematic review by Hirschfeld, Adam S

“…Various neurological symptoms have been confirmed in the course of SARS-CoV-2 infection. Some of these are undoubtedly the aftermath of the developing…”
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Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis by Adam, Sebastian, Zheng, Dazhong, Klein, Andreas, Volz, Carsten, Mullen, William, Shirran, Sally L., Smith, Brian O., Kalinina, Olga V., Müller, Rolf, Koehnke, Jesko

“…Ribosomally synthesized and post-translationally modified peptide natural products have provided many highly unusual scaffolds. This includes the intriguing…”
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Gold Loaded Polymersome Studies in Mammalian Cells by Zmijewski, Sebastian Adam

“…Polymersomes have potential for drug delivery applications due to their ability to efficiently encapsulate both hydrophobic and hydrophilic molecules. The…”
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Pineapple Lectin AcmJRL Binds SARS‐CoV‐2 Spike Protein in a Carbohydrate‐Dependent Fashion by Meiers, Joscha, Dastbaz, Jan, Adam, Sebastian, Rasheed, Sari, Kirsch, Susanne H., Meiser, Peter, Gross, Peter, Müller, Rolf, Titz, Alexander

“…The highly glycosylated spike protein of SARS‐CoV‐2 is essential for infection and constitutes a prime target for antiviral agents and vaccines. The…”
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