Search Results - "Adam, R M"

Multiciliated ependymal cells: an update on biology and pathology in the adult brain by Groh, Adam M. R., Song, Yeji Lori, Tea, Fiona, Lu, Brianna, Huynh, Stephanie, Afanasiev, Elia, Bigotte, Maxime, Del Bigio, Marc R., Stratton, Jo Anne

“…Mature multiciliated ependymal cells line the cerebral ventricles where they form a partial barrier between the cerebrospinal fluid (CSF) and brain parenchyma…”
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Correction: Multiciliated ependymal cells: an update on biology and pathology in the adult brain by Groh, Adam M. R., Song, Yeji Lori, Tea, Fiona, Lu, Brianna, Huynh, Stephanie, Afanasiev, Elia, Bigotte, Maxime, Del Bigio, Marc R., Stratton, Jo Anne

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Role of Proteome Physical Chemistry in Cell Behavior by Ghosh, Kingshuk, de Graff, Adam M. R, Sawle, Lucas, Dill, Ken A

“…We review how major cell behaviors, such as bacterial growth laws, are derived from the physical chemistry of the cell’s proteins. On one hand, cell actions…”
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A scoping review assessing the usability of digital health technologies targeting people with multiple sclerosis by Tea, Fiona, Groh, Adam M. R., Lacey, Colleen, Fakolade, Afolasade

“…Digital health technologies (DHTs) have become progressively more integrated into the healthcare of people with multiple sclerosis (MS). To ensure that DHTs…”
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Analysis of the microglia transcriptome across the human lifespan using single cell RNA sequencing by Yaqubi, Moein, Groh, Adam M R, Dorion, Marie-France, Afanasiev, Elia, Luo, Julia Xiao Xuan, Hashemi, Hadi, Sinha, Sarthak, Kieran, Nicholas W, Blain, Manon, Cui, Qiao-Ling, Biernaskie, Jeff, Srour, Myriam, Dudley, Roy, Hall, Jeffery A, Sonnen, Joshua A, Arbour, Nathalie, Prat, Alexandre, Stratton, Jo Anne, Antel, Jack, Healy, Luke M

“…Microglia are tissue resident macrophages with a wide range of critically important functions in central nervous system development and homeostasis. In this…”
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Pathogenic role of autoantibodies at the ependyma in autoimmune disorders of the central nervous system by Bigotte, Maxime, Groh, Adam M. R., Marignier, Romain, Stratton, Jo Anne

“…Ependymal cells make up the epithelial monolayer that lines the brain ventricles and the spinal cord central canal that are filled with cerebrospinal fluid…”
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A Pilot Study of a Physical Therapy Cadaveric Anatomy Course: Assessing the Impact of Examination Format on the Learning Environment by Fournier, Dale E., Groh, Adam M. R.

“…Anatomy education continues to evolve in health professional programs as curricula shift to competency‐based models and contact hours decrease. These changes…”
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A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups by Sulong, Sarina, Moorman, Anthony V., Irving, Julie A.E., Strefford, Jonathan C., Konn, Zoe J., Case, Marian C., Minto, Lynne, Barber, Kerry E., Parker, Helen, Wright, Sarah L., Stewart, Adam R.M., Bailey, Simon, Bown, Nick P., Hall, Andrew G., Harrison, Christine J.

“…Inactivation of the tumor suppressor gene, CDKN2A, can occur by deletion, methylation, or mutation. We assessed the principal mode of inactivation in childhood…”
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Heterogeneity of mature oligodendrocytes in the central nervous system by Weng, Chao, Groh, Adam M R, Yaqubi, Moein, Cui, Qiao-Ling, Stratton, Jo Anne, Moore, G R Wayne, Antel, Jack P

“…Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system…”
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DNA Bending through Large Angles Is Aided by Ionic Screening by Spiriti, Justin, Kamberaj, Hiqmet, de Graff, Adam M. R, Thorpe, M. F, van der Vaart, Arjan

“…We used adaptive umbrella sampling on a modified version of the roll angle to simulate the bending of DNA dodecamers. Simulations were carried out with the…”
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Proteostasis collapse is a driver of cell aging and death by Santra, Mantu, Dill, Ken A., de Graff, Adam M. R.

“…What molecular processes drive cell aging and death? Here, we model how proteostasis—i.e., the folding, chaperoning, and maintenance of protein…”
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The anatomy of the infrarenal lumbar splanchnic nerves in human cadavers: implications for retroperitoneal nerve‐sparing surgery by Beveridge, Tyler S., Fournier, Dale E., Groh, Adam M.R., Johnson, Marjorie, Power, Nicholas E., Allman, Brian L.

“…Injury to the nerves of the aortic‐ and superior hypogastric plexuses during retroperitoneal surgery often results in significant post‐operative complications,…”
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Scaffold attachment factor B1 regulates the androgen receptor in concert with the growth inhibitory kinase MST1 and the methyltransferase EZH2 by Mukhopadhyay, N K, Kim, J, You, S, Morello, M, Hager, M H, Huang, W-C, Ramachandran, A, Yang, J, Cinar, B, Rubin, M A, Adam, R M, Oesterreich, S, Di Vizio, D, Freeman, M R

“…The androgen receptor (AR) is a transcription factor that employs many diverse interactions with coregulatory proteins in normal physiology and in prostate…”
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Ghost cells: Wilder Penfield and the characterization of glia and glial pathology, 1924-1932 by Groh, Adam M R, Leblanc, Richard

“…Wilder Penfield is known for his contributions to the structure-function relationship of the brain and for the surgical treatment of focal epilepsy. Less well…”
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The long-wavelength limit of the structure factor of amorphous silicon and vitreous silica by De Graff, Adam M. R., Thorpe, M. F.

“…Liquids are in thermal equilibrium and have a non‐zero structure factor = = in the long‐wavelength limit where is the number density, is the temperature, is…”
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Burnout in Medical Oncology Fellows: a Prospective Multicenter Cohort Study in Brazilian Institutions by Cubero, Daniel I. G., Fumis, Renata Rego Lins, de Sá, Thiago Hérick, Dettino, Aldo, Costa, Felipe Osório, Van Eyll, Brigitte M. R. H. Adam, Beato, Carlos, Peria, Fernanda Maris, Mota, Augusto, Altino, José, Azevedo, Sérgio Jobim, da Rocha Filho, Duílio Reis, Moura, Melba, Lessa, Álvaro Edson Ramos, del Giglio, Auro

“…Burnout syndrome is a common occurrence among oncologists. Doctors enrolled in residency programs in clinical oncology are exposed to similar risk factors;…”
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Technology, policy and politics: critical success factors in high-technology infrastructure projects by Adam, R. M.

“…The article examines critical success factors in high technology projects by comparing the Square Kilometre Array, the Pebble Bed Modular Reactor and the…”
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Mechanical Strain Delivers Anti-apoptotic and Proliferative Signals to Gingival Fibroblasts by Danciu, T.E., Gagari, E., Adam, R.M., Damoulis, P.D., Freeman, M.R.

“…Physical forces play a critical role in the survival and proliferation of many cell types, including fibroblasts. Gingival fibroblasts are exposed to…”
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Innervation of the Human Intervertebral Disc: A Scoping Review by Groh, Adam M R, Fournier, Dale E, Battié, Michele C, Séguin, Cheryle A

“…Abstract Objective Back pain is an elusive symptom complicated by a variety of possible causes, precipitating and maintaining factors, and consequences…”
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The phosphatidylinositol 3'-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells by JIANQING LIN, ADAM, R. M, SANTIESTEVAN, E, FREEMAN, M. R

“…Intracellular signaling pathways that mediate survival of prostate carcinoma (PCa) cells are poorly understood. We examined the potential role of the…”
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