Search Results - "Adam, N. R."
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Regulation of Peripheral Inflammation by a Non-Viable, Non-Colonizing Strain of Commensal Bacteria
Published in Frontiers in immunology (02-02-2022)“…The gastrointestinal tract represents one of the largest body surfaces that is exposed to the outside world. It is the only mucosal surface that is required to…”
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Forecasting of peak electricity demand in Mauritius using the non-homogeneous Gompertz diffusion process
Published in Energy (Oxford) (01-12-2011)“…In this study, the non-homogeneous Gompertz diffusion process (NHGDP) is used to model the monthly peak electricity demand in Mauritius in order to predict the…”
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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
Published in Cancer cell (11-01-2021)“…Cancer immunotherapy shows limited efficacy against many solid tumors that originate from epithelial tissues, including triple-negative breast cancer (TNBC)…”
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A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
Published in Cell (01-11-2018)“…Immune checkpoint inhibitors (ICIs) produce durable responses in some melanoma patients, but many patients derive no clinical benefit, and the molecular…”
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Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells
Published in The Journal of cell biology (03-09-2018)“…Natural Killer (NK) cells can engage multiple virally infected or tumor cells sequentially and deliver perforin for cytolytic killing of these targets. Using…”
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The immune synapse clears and excludes molecules above a size threshold
Published in Nature communications (19-11-2014)“…Natural killer cells assess target cell health via interactions at the immune synapse (IS) that facilitates signal integration and directed secretion. Here we…”
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Elevated Atmospheric CO2 Improved Sorghum Plant Water Status by Ameliorating the Adverse Effects of Drought
Published in The New phytologist (01-11-2001)“…• The interactive effects of atmospheric CO2 concentration and soil-water content on grain sorghum (Sorghum bicolor) are reported here. • Sorghum plants were…”
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CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells
Published in Cancer discovery (01-08-2021)“…A number of cancer drugs activate innate immune pathways in tumor cells but unfortunately also compromise antitumor immune function. We discovered that…”
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The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection
Published in Nature immunology (01-07-2017)“…Wucherpfennig and colleagues show that the microRNA miR-31 increases the sensitivity of T cells to type I interferons, which interferes with effector T cell…”
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Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Patients with melanoma resistant to RAF/MEK inhibitors (RMi) are frequently resistant to other therapies, such as immune checkpoint inhibitors (ICI), and…”
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CO2 enrichment increases water‐use efficiency in sorghum
Published in The New phytologist (01-08-2001)“…Summary • Sorghum (Sorghum bicolor) was grown for two consecutive seasons at Maricopa, AZ, USA, using the free‐air CO2 enrichment (FACE) approach to…”
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Free-air CO2 enrichment effects on the energy balance and evapotranspiration of sorghum
Published in Agricultural and forest meteorology (20-07-2004)“…Increasing atmospheric carbon dioxide (CO2) likely will affect future water requirements of most plants, including agricultural crops. This research quantifies…”
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Development of C4 photosynthesis in sorghum leaves grown under free‐air CO2 enrichment (FACE)
Published in Journal of experimental botany (01-08-2003)“…The developmental pattern of C4 expression has been well characterized in maize and other C4 plants. However, few reports have explored the possibility that…”
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Type I interferon is required for T helper (Th) 2 induction by dendritic cells
Published in The EMBO journal (15-08-2017)“…Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as well as being responsible for widespread suffering in allergies…”
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Genetic screens to study the immune system in cancer
Published in Current opinion in immunology (01-08-2016)“…Highlights • Powerful genetic tools are now available to study immune pathways in tumors. • Pooled screens enable simultaneous investigation of thousands of…”
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An authorization system for digital libraries
Published in The VLDB journal (01-08-2002)“…Digital Libraries (DLs) introduce several challenging requirements with respect to the formulation, specification, and enforcement of adequate data protection…”
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Multipurpose Cryogenic Surface Apparatus: A Liquid Nitrogen‐Chilled Sample Tray
Published in Crop science (01-05-2001)“…The use of cryogenic techniques allows collection and storage of large numbers of samples for later processing for biochemical assays. In large field studies…”
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Nursing Knowledge of Alcohol and Other Drugs (AOD) in a Regional Health District: An Exploratory Study
Published in Issues in mental health nursing (02-12-2019)“…Nurses remain at the forefront of direct patient care due to the nature of their role; they are in a position to provide assessment, response and referral of…”
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A content-based authorization model for digital libraries
Published in IEEE transactions on knowledge and data engineering (01-03-2002)“…Digital libraries (DLs) introduce several challenging requirements with respect to the formulation, specification and enforcement of adequate data protection…”
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