Search Results - "Adam, Matti"

Diabetic Cardiovascular Disease Induced by Oxidative Stress by Kayama, Yosuke, Raaz, Uwe, Jagger, Ann, Adam, Matti, Schellinger, Isabel N, Sakamoto, Masaya, Suzuki, Hirofumi, Toyama, Kensuke, Spin, Joshua M, Tsao, Philip S

“…Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular…”
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MPO (Myeloperoxidase) Reduces Endothelial Glycocalyx Thickness Dependent on Its Cationic Charge by Manchanda, Kashish, Kolarova, Hana, Kerkenpaß, Christina, Mollenhauer, Martin, Vitecek, Jan, Rudolph, Volker, Kubala, Lukas, Baldus, Stephan, Adam, Matti, Klinke, Anna

“…OBJECTIVE—The leukocyte heme-enzyme MPO (myeloperoxidase) exerts proinflammatory effects on the vascular system primarily linked to its catalytic properties…”
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miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development by Maegdefessel, Lars, Spin, Joshua M., Raaz, Uwe, Eken, Suzanne M., Toh, Ryuji, Azuma, Junya, Adam, Matti, Nagakami, Futoshi, Heymann, Helen M., Chernugobova, Ekaterina, Jin, Hong, Roy, Joy, Hultgren, Rebecka, Caidahl, Kenneth, Schrepfer, Sonja, Hamsten, Anders, Eriksson, Per, McConnell, Michael V., Dalman, Ronald L., Tsao, Philip S.

“…Identification and treatment of abdominal aortic aneurysm (AAA) remain among the most prominent challenges in vascular medicine. MicroRNAs (miRNAs) are crucial…”
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MicroRNA-Mediated Therapy Modulating Blood–Brain Barrier Disruption Improves Vascular Cognitive Impairment by Toyama, Kensuke, Spin, Joshua M, Deng, Alicia C, Huang, Ting-Ting, Wei, Ke, Wagenhäuser, Markus U, Yoshino, Takuya, Nguyen, Huy, Mulorz, Joscha, Kundu, Soumajit, Raaz, Uwe, Adam, Matti, Schellinger, Isabel N, Jagger, Ann, Tsao, Philip S

“…OBJECTIVE—There are currently no effective treatments for the prevention of dementia associated with vascular cognitive impairment. MicroRNAs regulate gene…”
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The Enzymatic and Non-Enzymatic Function of Myeloperoxidase (MPO) in Inflammatory Communication by Kargapolova, Yulia, Geißen, Simon, Zheng, Ruiyuan, Baldus, Stephan, Winkels, Holger, Adam, Matti

“…Myeloperoxidase is a signature enzyme of polymorphonuclear neutrophils in mice and humans. Being a component of circulating white blood cells, myeloperoxidase…”
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Segmental aortic stiffening contributes to experimental abdominal aortic aneurysm development by Raaz, Uwe, Zöllner, Alexander M, Schellinger, Isabel N, Toh, Ryuji, Nakagami, Futoshi, Brandt, Moritz, Emrich, Fabian C, Kayama, Yosuke, Eken, Suzanne, Adam, Matti, Maegdefessel, Lars, Hertel, Thomas, Deng, Alicia, Jagger, Ann, Buerke, Michael, Dalman, Ronald L, Spin, Joshua M, Kuhl, Ellen, Tsao, Philip S

“…Stiffening of the aortic wall is a phenomenon consistently observed in age and in abdominal aortic aneurysm (AAA). However, its role in AAA pathophysiology is…”
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Meta-Analysis of Stroke and Mortality Rates in Patients Undergoing Valve-in-Valve Transcatheter Aortic Valve Replacement by Macherey, Sascha, Meertens, Max, Mauri, Victor, Frerker, Christian, Adam, Matti, Baldus, Stephan, Schmidt, Tobias

“…Background During the past decade, the use of transcatheter aortic valve replacement (TAVR) was extended beyond treatment-naïve patients and implemented for…”
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Myeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling by Mollenhauer, Martin, Friedrichs, Kai, Lange, Max, Gesenberg, Jan, Remane, Lisa, Kerkenpaß, Christina, Krause, Jenny, Schneider, Johanna, Ravekes, Thorben, Maass, Martina, Halbach, Marcel, Peinkofer, Gabriel, Saric, Tomo, Mehrkens, Dennis, Adam, Matti, Deuschl, Florian G, Lau, Denise, Geertz, Birgit, Manchanda, Kashish, Eschenhagen, Thomas, Kubala, Lukas, Rudolph, Tanja K, Wu, Yuping, Tang, W H Wilson, Hazen, Stanley L, Baldus, Stephan, Klinke, Anna, Rudolph, Volker

“…Ventricular arrhythmias remain the leading cause of death in patients suffering myocardial ischemia. Myeloperoxidase, a heme enzyme released by…”
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Vascular Ultrasound for In Vivo Assessment of Arterial Pathologies in a Murine Model of Atherosclerosis and Aortic Aneurysm by Hof, Alexander, Guthoff, Henning, Ahdab, Maysam, Landerer, Max, Schäkel, Jasper, Niehues, Jana, Schorscher, Maximilian, Zimmermann, Oscar, Winkels, Holger, von Stein, Philipp, Geißen, Simon, Baldus, Stephan, Adam, Matti, Mollenhauer, Martin, Mehrkens, Dennis

“…Vascular diseases like atherosclerosis and abdominal aortic aneurysm (AAA) are common pathologies in the western world, promoting various potentially fatal…”
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Comparison of Resting Full-Cycle Ratio and Fractional Flow Reserve in a German Real-World Cohort by Wienemann, Hendrik, Meyer, Annika, Mauri, Victor, Baar, Till, Adam, Matti, Baldus, Stephan, Halbach, Marcel

“…The aim of this study was to evaluate non-hyperemic resting pressure ratios (NHPRs), especially the novel "resting full-cycle ratio" (RFR; lowest pressure…”
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Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm by Adam, Matti, Kooreman, Nigel Geoffrey, Jagger, Ann, Wagenhäuser, Markus U, Mehrkens, Dennis, Wang, Yongming, Kayama, Yosuke, Toyama, Kensuke, Raaz, Uwe, Schellinger, Isabel N, Maegdefessel, Lars, Spin, Joshua M, Hamming, Jaap F, Quax, Paul H.A, Baldus, Stephan, Wu, Joseph C, Tsao, Philip S

“…OBJECTIVE—Recruitment of immunologic competent cells to the vessel wall is a crucial step in formation of abdominal aortic aneurysms (AAA). Innate immunity…”
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Myeloperoxidase induces monocyte migration and activation after acute myocardial infarction by Peters, Vera B M, Matheis, Friederike, Erdmann, Immanuel, Nemade, Harshal N, Muders, David, Toubartz, Martin, Torun, Merve, Mehrkens, Dennis, Geißen, Simon, Nettersheim, Felix Sebastian, Picard, Felix, Guthoff, Henning, Hof, Alexander, Arkenberg, Per, Arand, Birgit, Klinke, Anna, Rudolph, Volker, Hansen, Hinrich Peter, Bachurski, Daniel, Adam, Matti, Hoyer, Friedrich Felix, Winkels, Holger, Baldus, Stephan, Mollenhauer, Martin

“…Myocardial infarction (MI) is a significant contributor to morbidity and mortality worldwide. Many individuals who survive the acute event continue to…”
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Induction of atrial fibrillation by neutrophils critically depends on CD11b/CD18 integrins by Friedrichs, Kai, Adam, Matti, Remane, Lisa, Mollenhauer, Martin, Rudolph, Volker, Rudolph, Tanja K, Andrié, René P, Stöckigt, Florian, Schrickel, Jan W, Ravekes, Thorben, Deuschl, Florian, Nickenig, Georg, Willems, Stephan, Baldus, Stephan, Klinke, Anna

“…Recent observational clinical and ex-vivo studies suggest that inflammation and in particular leukocyte activation predisposes to atrial fibrillation (AF)…”
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Chronic Nicotine Exposure Induces Murine Aortic Remodeling and Stiffness Segmentation-Implications for Abdominal Aortic Aneurysm Susceptibility by Wagenhäuser, Markus U, Schellinger, Isabel N, Yoshino, Takuya, Toyama, Kensuke, Kayama, Yosuke, Deng, Alicia, Guenther, Sabina P, Petzold, Anne, Mulorz, Joscha, Mulorz, Pireyatharsheny, Hasenfuß, Gerd, Ibing, Wiebke, Elvers, Margitta, Schuster, Andreas, Ramasubramanian, Anand K, Adam, Matti, Schelzig, Hubert, Spin, Joshua M, Raaz, Uwe, Tsao, Philip S

“…Arterial stiffness is a significant risk factor for many cardiovascular diseases, including abdominal aortic aneurysms (AAA). Nicotine, the major active…”
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Low Left-Ventricular Ejection Fraction as a Predictor of Intraprocedural Cardiopulmonary Resuscitation in Patients Undergoing Transcatheter Aortic Valve Implantation by Gerfer, Stephen, Großmann, Clara, Gablac, Hannah, Elderia, Ahmed, Wienemann, Hendrik, Krasivskyi, Ihor, Mader, Navid, Lee, Samuel, Mauri, Victor, Djordjevic, Ilija, Adam, Matti, Kuhn, Elmar, Baldus, Stephan, Eghbalzadeh, Kaveh, Wahlers, Thorsten

“…Transcatheter aortic valve replacement (TAVR) has become an established alternative to surgical aortic valve replacement (AVR) for patients with…”
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Transcatheter Aortic Valve Implantation with ACURATE neo: Results from the PROGRESS PVL Registry by Kim, Won-Keun, Thiele, Holger, Linke, Axel, Kuntze, Thomas, Fichtlscherer, Stephan, Webb, John, Chu, Michael W. A., Adam, Matti, Schymik, Gerhard, Geisler, Tobias, Kharbanda, Rajesh, Christen, Thomas, Allocco, Dominic

“…Objectives. The PROGRESS PVL registry evaluated transcatheter aortic valve implantation (TAVI) in patients treated with ACURATE neo, a supra-annular…”
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Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse by Hennigs, Jan K, Müller, Julia, Adam, Matti, Spin, Joshua M, Riedel, Emilia, Graefen, Markus, Bokemeyer, Carsten, Sauter, Guido, Huland, Hartwig, Schlomm, Thorsten, Minner, Sarah

“…Somatostatin receptor subtype 2 (SSTR2) is the most frequently expressed SSTR subtype in normal human tissues. SSTR2 expression is differentially regulated in…”
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Nitro-Oleic Acid (NO 2 -OA) Improves Systolic Function in Dilated Cardiomyopathy by Attenuating Myocardial Fibrosis by Braumann, Simon, Schumacher, Wibke, Im, Nam Gyu, Nettersheim, Felix Sebastian, Mehrkens, Dennis, Bokredenghel, Senai, Hof, Alexander, Nies, Richard Julius, Adler, Christoph, Winkels, Holger, Knöll, Ralph, Freeman, Bruce A, Rudolph, Volker, Klinke, Anna, Adam, Matti, Baldus, Stephan, Mollenhauer, Martin, Geißen, Simon

“…Nitro-oleic acid (NO -OA), a nitric oxide (NO)- and nitrite (NO )-derived electrophilic fatty acid metabolite, displays anti-inflammatory and anti-fibrotic…”
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Stamp2 Protects From Maladaptive Structural Remodeling and Systolic Dysfunction in Post-Ischemic Hearts by Attenuating Neutrophil Activation by Mollenhauer, Martin, Bokredenghel, Senai, Geißen, Simon, Klinke, Anna, Morstadt, Tobias, Torun, Merve, Strauch, Sabrina, Schumacher, Wibke, Maass, Martina, Konradi, Jürgen, Peters, Vera B M, Berghausen, Eva, Vantler, Marius, Rosenkranz, Stephan, Mehrkens, Dennis, Braumann, Simon, Nettersheim, Felix, Hof, Alexander, Simsekyilmaz, Sakine, Winkels, Holger, Rudolph, Volker, Baldus, Stephan, Adam, Matti, Freyhaus, Henrik Ten

“…The six-transmembrane protein of prostate 2 (Stamp2) acts as an anti-inflammatory protein in macrophages by protecting from overt inflammatory signaling and…”
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Impact of transradial versus transfemoral access for preprocedural coronary angiography on TAVR-associated complications by Al-Kassou, Baravan, Al-Shaikh, Hasanin, Aksoy, Adem, Shamekhi, Jasmin, Zietzer, Andreas, Sugiura, Atsushi, Veulemans, Verena, Adam, Matti, Grube, Eberhard, Bakhtiary, Farhad, Zimmer, Sebastian, Kelm, Malte, Baldus, Stephan, Nickenig, Georg, Sedaghat, Alexander

“…Transradial access for preprocedural coronary angiography was associated with lower rates of periprocedural vascular injury and major vascular complications…”
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