Search Results - "Adam, Cloé"
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RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia
Published in Nature communications (21-03-2018)“…The roles of RNA 5-methylcytosine (RNA:m 5 C) and RNA:m 5 C methyltransferases (RCMTs) in lineage-associated chromatin organization and drug…”
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Human Osteoblast-Conditioned Media Can Influence Staphylococcus aureus Biofilm Formation
Published in International journal of molecular sciences (19-11-2022)“…Osteoblasts are bone-forming and highly active cells participating in bone homeostasis. In the case of osteomyelitis and more specifically prosthetic joint…”
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UVC Box: An Effective Way to Quickly Decontaminate Healthcare Facilities' Wheelchairs
Published in Life (Basel, Switzerland) (01-02-2024)“…Disinfection in the hospital environment remains challenging, especially for wide and structurally complex objects such as beds or wheelchairs. Indeed, the…”
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The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39)
Published in Biochemistry (Easton) (29-03-2011)“…The ΔE693 (Japanese) mutation of the β-amyloid precursor protein leads to production of ΔE22-Aβ peptides such as ΔE22-Aβ(1-39). Despite reports that these…”
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t(11;16)(q23;p13)/KMT2A-CREBBP in hematologic malignancies: presumptive evidence of myelodysplasia or therapy-related neoplasm?
Published in Annals of hematology (01-03-2020)“…Fusion partners of KMT2A affect disease phenotype and influence the current World Health Organization classification of hematologic neoplasms. The…”
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Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia
Published in Nature communications (06-06-2018)“…In the originally published version of this Article, the GAPDH loading control blot in Fig. 1a was inadvertently replaced with a duplicate of the DNMT2 blot in…”
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The Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40 into Atypical Fibrils by ΔE22-Aβ1−39
Published in Biochemistry (Easton) (29-03-2011)“…The ΔE693 (Japanese) mutation of the β-amyloid precursor protein leads to production of ΔE22-Aβ peptides such as ΔE22-Aβ1−39. Despite reports that these…”
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Prediction of Coagulation Testing in Underfilled Patient Samples
Published in American journal of clinical pathology (01-03-2017)Get full text
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FLT3 Inhibitors for the Treatment of Acute Myeloid Leukemia: An Evaluation of Efficacy of Target Inhibition and Relationship to Disease Progression
Published in Blood (03-12-2015)“…Introduction FLT3 is a receptor tyrosine kinase that plays a role in hematopoietic stem/progenitor cell proliferation and survival and is frequently found to…”
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Identification of Specific Hnrnps As Novel Therapeutic Targets and Responsive Indicators of KPT330 (selinexor) in Leukemia
Published in Blood (02-12-2016)“…Background: Activenuclear-cytoplasmic shuttling of proteins and RNAs, such as heterogeneous ribonucleoproteins (hnRNPs), is essential for the normal function…”
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Bone Marrow Collection: Comparison of Unassisted vs Assisted Bedside Collections by a Laboratory Technologist
Published in American journal of clinical pathology (01-04-2022)“…Bone marrow collections are often difficult, and creating quality smears and touch preparations at the bedside can prove challenging. The objective of this…”
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RNA:m5c/Methyltransferases Mediate Chromatin Organization and 5-Azacytidine Response/Resistance in Leukemia
Published in Blood (08-12-2017)“…Background: The roles of RNA modifications and RNA-modifying enzymes (writers and erasers) in the regulation of chromatin structure and drug…”
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Abstract 4470: RNA m5C methyltransferases and hnRNPK mediate disease-associated chromatin structure and drug resistance in leukemia
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract The mechanisms governing disease-associated chromatin organization and drug selectivity are poorly understood. Our epigenetic drug screening…”
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Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex
Published in Blood (02-12-2016)“…Background: BETs are evolutionarily conserved proteins that specifically bind to acetyl-lysines on histones and other proteins to recruit transcriptional…”
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P2‐248: Approaches to NMR of mixed Aβ oligomers
Published in Alzheimer's & dementia (01-07-2011)Get full text
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Approaches to NMR of mixed Aβ oligomers
Published in Alzheimer's & dementia (01-07-2011)Get full text
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The ΔE22 Aβ “Japanese” mutant: Biophysical characterization and implications for Alzheimer's disease pathogenesis
Published 01-01-2011“…Alzheimer's Disease is a condition marked by the development of aggregates of the Aβ peptide. Despite extensive research into the development of Alzheimer's…”
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Dissertation