Search Results - "Acuña, Sergio A."

Oncologic Outcomes Following Laparoscopic versus Open Resection of pT4 Colon Cancer: A Systematic Review and Meta-analysis by Feinberg, Adina E, Chesney, Tyler R, Acuna, Sergio A, Sammour, Tarik, Quereshy, Fayez A

“…BACKGROUND:Locally advanced colon cancer is considered a relative contraindication for laparoscopic resection, and clinical trials addressing the oncologic…”
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Association of perioperative red blood cell transfusions with all-cause and cancer-specific death in patients undergoing surgery for gastrointestinal cancer: Long-term outcomes from a population-based cohort by Zuckerman, Jesse, Coburn, Natalie, Callum, Jeannie, Mahar, Alyson L., Acuña, Sergio A., Guttman, Matthew P., Zuk, Victoria, Lin, Yulia, Turgeon, Alexis F., Martel, Guillaume, Hallet, Julie

“…Red blood cell transfusions are common in patients undergoing gastrointestinal cancer surgery. Yet, to adequately balance their risks and benefits, clinicians…”
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Cancer Mortality Among Recipients of Solid-Organ Transplantation in Ontario, Canada by Acuna, Sergio A, Fernandes, Kimberly A, Daly, Corinne, Hicks, Lisa K, Sutradhar, Rinku, Kim, S Joseph, Baxter, Nancy N

“…Solid-organ transplant recipients (SOTRs) are at greater risk of developing some cancers than the general population; however, because they are also at…”
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Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials by Pol, Jonathan G., Acuna, Sergio A., Yadollahi, Beta, Tang, Nan, Stephenson, Kyle B., Atherton, Matthew J., Hanwell, David, El-Warrak, Alexander, Goldstein, Alyssa, Moloo, Badru, Turner, Patricia V., Lopez, Roberto, LaFrance, Sandra, Evelegh, Carole, Denisova, Galina, Parsons, Robin, Millar, Jamie, Stoll, Gautier, Martin, Chantal G., Pomoransky, Julia, Breitbach, Caroline J., Bramson, Jonathan L., Bell, John C., Wan, Yonghong, Stojdl, David F., Lichty, Brian D., McCart, J. Andrea

“…Multiple immunotherapeutics have been approved for cancer patients, however advanced solid tumors are frequently refractory to treatment. We evaluated the…”
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Vaccinia virus and peptide-receptor radiotherapy synergize to improve treatment of peritoneal carcinomatosis by Ottolino-Perry, Kathryn, Mealiea, David, Sellers, Clara, Acuna, Sergio A., Angarita, Fernando A., Okamoto, Lili, Scollard, Deborah, Ginj, Mihaela, Reilly, Raymond, McCart, J. Andrea

“…Tumor-specific overexpression of receptors enables a variety of targeted cancer therapies, exemplified by peptide-receptor radiotherapy (PRRT) for somatostatin…”
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Outcomes of resection for locoregionally recurrent colon cancer: A systematic review by Chesney, Tyler R., MD, MSc, Nadler, Ashlie, MD, Acuna, Sergio A., MD, Swallow, Carol J., MD, PhD

“…Background The value of resection for locoregionally recurrent colon cancer (LRCC) is controversial. We aimed to describe the outcomes of resection for LRCC…”
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Etiology of increased cancer incidence after solid organ transplantation by Acuna, Sergio A.

“…Over the past decades, there has been an encouraging increase in survival after solid organ transplantation. However, with longer life spans, more transplant…”
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Colecistitis calculosa aguda by Angarita, Fernando A., Acuña, Sergio A., Jimenez, Carolina, Garay, Javier, Gömez, David, Domínguez, Luis Carlos

“…La colecistitis calculosa aguda es la causa más importante de colecistectomías en el mundo. En esta revisión de tema se resume la fisiopatología del proceso…”
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Opioid Use After Discharge in Postoperative Patients: A Systematic Review by Feinberg, Adina E, Chesney, Tyler R, Srikandarajah, Sanjho, Acuna, Sergio A, McLeod, Robin S

“…BACKGROUND:Over the past 2 decades, there has been an increase in opioid use and subsequently, opioid deaths. The amount of opioid prescribed to surgical…”
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Thrombocytosis in splenic trauma: In-hospital course and association with venous thromboembolism by Chia, Tze L., MD, Chesney, Tyler R., MD MSc, Isa, David, MD, Mnatzakanian, Gevork, MD, Colak, Errol, MD, Belmont, Caio, MD, Hirpara, Dhruvin, BHSc, Veigas, Precilla V., PhD, Acuna, Sergio A., MD, Rizoli, Sandro, MD PhD, Rezende-Neto, Joao, MD PhD

“…Abstract Introduction Thrombocytosis is common following elective splenectomy and major trauma. However, little is known about the in-hospital course of…”
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Meta-analysis of noninferiority and equivalence trials: ignoring trial design leads to differing and possibly misleading conclusions by Acuna, Sergio A., Dossa, Fahima, Baxter, Nancy

“…The objective of the study is to examine the analytic approach of meta-analyses that include noninferiority or equivalence (NI/EQ) trials. We used Scopus to…”
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Comment on “Long-term Outcome of Surgery Versus Conservative Management for Recurrent and Ongoing Complaints After an Episode of Diverticulitis”: Statistically Significant Results Are Not Necessarily Clinically Important by Acuna, Sergio A., Dossa, Fahima

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Chest Wall Resection for Recurrent Breast Cancer in the Modern Era: A Systematic Review and Meta-analysis by Wakeam, Elliot, Acuna, Sergio A, Keshavjee, Shaf

“…OBJECTIVE:To review the literature on chest wall resection for recurrent breast cancer and evaluate overall survival (OS) and quality-of-life (QOL) outcomes…”
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Harmful or Physiologic: Diagnosing Fibrinolysis Shutdown in a Trauma Cohort With Rotational Thromboelastometry by Gomez-Builes, J. Carolina, Acuna, Sergio A., Nascimento, Bartolomeu, Madotto, Fabiana, Rizoli, Sandro B.

“…BACKGROUND:Despite its central role in early trauma coagulopathy, abnormal fibrinolysis continues to be poorly understood. Excessive fibrinolysis is a known…”
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Propofol versus midazolam with or without short-acting opioids for sedation in colonoscopy: a systematic review and meta-analysis of safety, satisfaction, and efficiency outcomes by Dossa, Fahima, Medeiros, Braeden, Keng, Christine, Acuna, Sergio A., Baxter, Nancy N.

“…Propofol is increasingly being used for sedation in colonoscopy; however, its benefits over midazolam (± short-acting opioids) are not well quantified. The…”
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Solid Organ Transplantation in Patients with Preexisting Malignancies in Remission: A Propensity Score Matched Cohort Study by Acuna, Sergio A, Sutradhar, Rinku, Kim, S Joseph, Baxter, Nancy N

“…BACKGROUNDSolid organ transplant recipients (SOTR) with pretransplant malignancies (PTM) have worse overall survival (OS) compared to recipients without…”
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The Fragility Index-P Values Reimagined, Flaws and All by Acuna, Sergio A, Sue-Chue-Lam, Colin, Dossa, Fahima

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A note on competing risks in analyses of cancer‐specific mortality by Acuna, Sergio A., Dossa, Fahima

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Incorporating Patient Preferences in Noninferiority Trials by Acuna, Sergio A, Chesney, Tyler R, Baxter, Nancy N

“…This Viewpoint discusses the selection and interpretation of noninferiority margins (ΔNIs) in noninferiority trials, reviews techniques for eliciting patient…”
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Laparoscopic and robotic hysterectomy in endometrial cancer patients with obesity: a systematic review and meta-analysis of conversions and complications by Cusimano, Maria C., Simpson, Andrea N., Dossa, Fahima, Liani, Valentina, Kaur, Yuvreet, Acuna, Sergio A., Robertson, Deborah, Satkunaratnam, Abheha, Bernardini, Marcus Q., Ferguson, Sarah E., Baxter, Nancy N.

“…Robotic assistance may facilitate completion of minimally invasive hysterectomy, which is the standard of care for the treatment of early-stage endometrial…”
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