Search Results - "Actkins, Ky’Era"

Characterizing the Clinical and Genetic Spectrum of Polycystic Ovary Syndrome in Electronic Health Records by Actkins, Ky’Era V, Singh, Kritika, Hucks, Donald, Velez Edwards, Digna R, Aldrich, Melinda, Cha, Jeeyeon, Wellons, Melissa, Davis, Lea K

“…Abstract Context Polycystic ovary syndrome (PCOS) is one of the leading causes of infertility, yet current diagnostic criteria are ineffective at identifying…”
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Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease by Dennis, Jessica K, Sealock, Julia M, Straub, Peter, Lee, Younga H, Hucks, Donald, Actkins, Ky'Era, Faucon, Annika, Feng, Yen-Chen Anne, Ge, Tian, Goleva, Slavina B, Niarchou, Maria, Singh, Kritika, Morley, Theodore, Smoller, Jordan W, Ruderfer, Douglas M, Mosley, Jonathan D, Chen, Guanhua, Davis, Lea K

“…Clinical laboratory (lab) tests are used in clinical practice to diagnose, treat, and monitor disease conditions. Test results are stored in electronic health…”
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A genome-wide association study of polycystic ovary syndrome identified from electronic health records by Zhang, Yanfei, Ho, Kevin, Keaton, Jacob M., Hartzel, Dustin N., Day, Felix, Justice, Anne E., Josyula, Navya S., Pendergrass, Sarah A., Actkins, Ky'Era, Davis, Lea K., Velez Edwards, Digna R., Holohan, Brody, Ramirez, Andrea, Stanaway, Ian B., Crosslin, David R., Jarvik, Gail P., Sleiman, Patrick, Hakonarson, Hakon, Williams, Marc S., Lee, Ming Ta Michael

“…Polycystic ovary syndrome is the most common endocrine disorder affecting women of reproductive age. A number of criteria have been developed for clinical…”
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Three-dimensional mitochondria reconstructions of murine cardiac muscle changes in size across aging by Vue, Zer, Neikirk, Kit, Vang, Larry, Garza-Lopez, Edgar, Christensen, Trace A, Shao, Jianqiang, Lam, Jacob, Beasley, Heather K, Marshall, Andrea G, Crabtree, Amber, Anudokem, Jr, Josephs, Rodriguez, Benjamin, Kirk, Benjamin, Bacevac, Serif, Barongan, Taylor, Shao, Bryanna, Stephens, Dominique C, Kabugi, Kinuthia, Koh, Ho-Jin, Koh, Alice, Evans, Chantell S, Taylor, Brittany, Reddy, Anilkumar K, Miller-Fleming, Tyne, Actkins, Ky'Era V, Zaganjor, Elma, Daneshgar, Nastaran, Murray, Sandra A, Mobley, Bret C, Damo, Steven M, Gaddy, Jennifer A, Riggs, Blake, Wanjalla, Celestine, Kirabo, Annet, McReynolds, Melanie, Gomez, Jose A, Phillips, Mark A, Exil, Vernat, Dai, Dao-Fu, Hinton, Jr, Antentor

“…With sparse treatment options, cardiac disease remains a significant cause of death among humans. As a person ages, mitochondria breakdown and the heart…”
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Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey by Actkins, Ky'Era V, Srinivasan, Swetha, Spees, Lisa P, Turbitt, Erin, Allen, Caitlin G, Roberts, Megan C

“…Lynch syndrome is the most common inherited cancer syndrome that increases the risk of developing colorectal and endometrial cancer. Universal screening…”
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Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference by Meng, Xiangrui, Navoly, Georgina, Giannakopoulou, Olga, Levey, Daniel F., Koller, Dora, Pathak, Gita A., Koen, Nastassja, Lin, Kuang, Adams, Mark J., Rentería, Miguel E., Feng, Yanzhe, Gaziano, J. Michael, Stein, Dan J., Zar, Heather J., Campbell, Megan L., van Heel, David A., Trivedi, Bhavi, Finer, Sarah, McQuillin, Andrew, Bass, Nick, Chundru, V. Kartik, Martin, Hilary C., Huang, Qin Qin, Valkovskaya, Maria, Chu, Chia-Yi, Kanjira, Susan, Kuo, Po-Hsiu, Chen, Hsi-Chung, Tsai, Shih-Jen, Liu, Yu-Li, Kendler, Kenneth S., Peterson, Roseann E., Cai, Na, Fang, Yu, Sen, Srijan, Scott, Laura J., Burmeister, Margit, Loos, Ruth J. F., Preuss, Michael H., Actkins, Ky’Era V., Davis, Lea K., Uddin, Monica, Wani, Agaz H., Wildman, Derek E., Aiello, Allison E., Ursano, Robert J., Kessler, Ronald C., Kanai, Masahiro, Okada, Yukinori, Sakaue, Saori, Rabinowitz, Jill A., Maher, Brion S., Uhl, George, Eaton, William, Cruz-Fuentes, Carlos S., Martinez-Levy, Gabriela A., Campos, Adrian I., Millwood, Iona Y., Chen, Zhengming, Li, Liming, Wassertheil-Smoller, Sylvia, Jiang, Yunxuan, Tian, Chao, Martin, Nicholas G., Mitchell, Brittany L., Byrne, Enda M., Awasthi, Swapnil, Coleman, Jonathan R. I., Ripke, Stephan, Sofer, Tamar, Walters, Robin G., McIntosh, Andrew M., Polimanti, Renato, Dunn, Erin C., Stein, Murray B., Gelernter, Joel, Lewis, Cathryn M., Kuchenbaecker, Karoline

“…Most genome-wide association studies (GWAS) of major depression (MD) have been conducted in samples of European ancestry. Here we report a multi-ancestry GWAS…”
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Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity by Mbarek, Hamdi, Gordon, Scott D, Duffy, David L, Hubers, Nikki, Mortlock, Sally, Beck, Jeffrey J, Hottenga, Jouke-Jan, Pool, René, Dolan, Conor V, Actkins, Ky’Era V, Gerring, Zachary F, Van Dongen, Jenny, Ehli, Erik A, Iacono, William G, Mcgue, Matt, Chasman, Daniel I, Gallagher, C Scott, Schilit, Samantha L P, Morton, Cynthia C, Paré, Guillaume, Willemsen, Gonneke, Whiteman, David C, Olsen, Catherine M, Derom, Catherine, Vlietinck, Robert, Gudbjartsson, Daniel, Cannon-Albright, Lisa, Krapohl, Eva, Plomin, Robert, Magnusson, Patrik K E, Pedersen, Nancy L, Hysi, Pirro, Mangino, Massimo, Spector, Timothy D, Palviainen, Teemu, Milaneschi, Yuri, Penninnx, Brenda W, Campos, Adrian I, Ong, Ken K, Perry, John R B, Lambalk, Cornelis B, Kaprio, Jaakko, Ólafsson, Ísleifur, Duroure, Karine, Revenu, Céline, Rentería, Miguel E, Yengo, Loic, Davis, Lea, Derks, Eske M, Medland, Sarah E, Stefansson, Hreinn, Stefansson, Kari, Del Bene, Filippo, Reversade, Bruno, Montgomery, Grant W, Boomsma, Dorret I, Martin, Nicholas G

“…Abstract STUDY QUESTION Which genetic factors regulate female propensity for giving birth to spontaneous dizygotic (DZ) twins? SUMMARY ANSWER We identified…”
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SOX6 expression and aneurysms of the thoracic and abdominal aorta by Carmona-Berrio, David, Adarve-Rengifo, Isabel, Marshall, Andrea G., Vue, Zer, Hall, Duane D., Miller-Fleming, Tyne W., Actkins, Ky’Era V., Beasley, Heather K., Almonacid, Paula M., Barturen-Larrea, Pierina, Wells, Quinn S., Lopez, Marcos G., Garza-Lopez, Edgar, Dai, Dao-Fu, Shao, Jianqiang, Neikirk, Kit, Billings, Frederic T., Curci, John A., Cox, Nancy J., Gama, Vivian, Hinton, Antentor, Gomez, Jose A.

“…Abdominal and thoracic aortic aneurysms (AAAs, TAAs) remain a major cause of deaths worldwide, in part due to the lack of reliable prognostic markers or early…”
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Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry by Burns, Kharis, Mullin, Benjamin H, Moolhuijsen, Loes M E, Laisk, Triin, Tyrmi, Jaakko S, Cui, Jinrui, Actkins, Ky'Era V, Louwers, Yvonne V, Davis, Lea K, Dudbridge, Frank, Azziz, Ricardo, Goodarzi, Mark O, Laivuori, Hannele, Mägi, Reedik, Visser, Jenny A, Laven, Joop S E, Wilson, Scott G, Day, Felix R, Stuckey, Bronwyn G A

“…Polycystic ovary syndrome (PCOS) is a complex multifactorial disorder with a substantial genetic component. However, the clinical manifestations of PCOS are…”
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Sex modifies the effect of genetic risk scores for polycystic ovary syndrome on metabolic phenotypes by Actkins, Ky'Era V, Jean-Pierre, Genevieve, Aldrich, Melinda C, Velez Edwards, Digna R, Davis, Lea K

“…Females with polycystic ovary syndrome (PCOS), the most common endocrine disorder in women, have an increased risk of developing cardiometabolic disorders such…”
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A quick guide to networking for scientists by Beasley, Heather K., Actkins, Ky’Era V., Marshall, Andrea G., Garza-Lopez, Edgar, Wanjalla, Celestine, Scudese, Estevão, Kirabo, Annet, Liu, Kaihua, Hinton, Antentor

“…Networking is an important skill for finding social relationships relevant to one’s career. However, networking can be difficult to navigate as different…”
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Fibroid Prevalence-Still So Much to Learn by Harmon, Quaker E, Actkins, Ky'Era V, Baird, Donna D

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UTILITY OF HORMONE GENETIC RISK SCORES IN IDENTIFYING REPRODUCTIVE DYSFUNCTION ASSOCIATED WITH POLYCYSTIC OVARY SYNDROME by Actkins, Ky'Era V., Davis, Lea K.

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Calcium-Sensing Receptor Polymorphisms at rs1801725 Are Associated with Increased Risk of Secondary Malignancies by Actkins, Ky'Era V, Beasley, Heather K, Faucon, Annika B, Davis, Lea K, Sakwe, Amos M

“…Dysregulation of systemic calcium homeostasis during malignancy is common in most patients with high-grade tumors. However, it remains unclear whether single…”
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A POLYCYSTIC OVARY SYNDROME DIAGNOSIS IS A MARKER OF SOCIOECONOMIC ADVANTAGE by Actkins, Ky'era V., Aldrich, Melinda, Davis, Lea K.

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Abstract 5127: Association of inactivating calcium sensing receptor exon 7 SNPs with hypercalcemia-related disease phenotypes by Actkins, Ky'Era, Beasley, Heather, Faucon, Annika, Davis, Lea, Sakwe, Amos

“…Abstract The calcium sensing receptor (CaSR) is a ubiquitously expressed G-protein coupled receptor known to be a major calcium sensor in most tissues and…”
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Abstract 2827: Inactivating calcium-sensing receptor polymorphisms at rs1801725 are associated with increased risk of secondary malignancies by Beasley, Heather K., Actkins, Ky'Era V., Faucon, Annika B., Davis, Lea K., Sakwe, Amos M.

“…Abstract The dysregulation of systemic calcium homeostasis during malignancy is common in most patients with high-grade tumors. The associated comorbidity is…”
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Abstract 1567: The role of the calcium-sensing receptor (CaSR) in the bone metastatic niche by Beasley, Heather K., Actkins, Ky'Era, Faucon, Annika, Whalen, Diva, Williams, Stephen, Korolkova, Olga, Sakwe, Amos

“…Abstract Cancer-induced hypercalcemia (CIH) is common in cancer patients with metastatic disease and in up to 30% of breast cancer cases without evidence of…”
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POLYCYSTIC OVARY SYNDROME COMORBIDITY PATTERNS DIFFER BETWEEN RACIALLY AND ETHNICALLY DIVERSE PATIENTS by Actkins, Ky'Era V., Aldrich, Melinda, Velez Edwards, Digna R., Davis, Lea K.

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IDENTIFICATION OF NOVEL PCOS-RISK ALLELES BY LARGE-SCALE GENOME WIDE META-ANALYSIS PROVIDES NEW INSIGHTS INTO BIOLOGICAL MECHANISMS AND CLINICAL HEALTH OUTCOMES by Moolhuijsen, Loes, Day, Felix R., Karaderi, Tugce, Mullin, Benjamin H., Zhu, Jia, Gualdo, Natàlia Pujol, Actkins, Ky'Era V., Welt, Corrine K., Louwers, Yvonne, Visser, Jenny A., Laven, Joop

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