Search Results - "Acta biochimica et biophysica Sinica"

Aquaporin 8ab is required in zebrafish embryonic intestine development by Wang, Shiping, Qin, Yinyin, Sheng, Jiajing, Duan, Xuchu, Shen, Lizong, Liu, Dong

“…The aquaporin 8 (AQP8) is a small integral membrane protein that selectively transports water and other small uncharged solutes across cell plasma membranes…”
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TGF-β signaling in cancer metastasis by Xie, Feng, Ling, Li, van Dam, Hans, Zhou, Fangfang, Zhang, Long

“…Abstract The transforming growth factor (TGF)-β signaling events are well known to control diverse processes and numerous responses, such as cell…”
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ROS signaling cascades: dual regulations for osteoclast and osteoblast by Tao, Huaqiang, Ge, Gaoran, Liang, Xiaolong, Zhang, Weicheng, Sun, Houyi, Li, Meng, Geng, Dechun

“…Abstract Accumulating evidence indicates that intracellular reactive oxygen species (ROS) production is highly involved in bone homeostasis by intervening…”
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Effects of cannabidiol interactions with Wnt/β-catenin pathway and PPARγ on oxidative stress and neuroinflammation in Alzheimer's disease by Vallée, Alexandre, Lecarpentier, Yves, Guillevin, Rémy, Vallée, Jean-Noël

“…Alzheimer's disease (AD) is a neurodegenerative disease, in which the primary etiology remains unknown. AD presents amyloid beta (Aβ) protein aggregation and…”
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TGF-β family co-receptor function and signaling by Nickel, Joachim, ten Dijke, Peter, Mueller, Thomas D

“…Abstract Transforming growth factor-β (TGF-β) family members, which include TGF-βs, activins and bone morphogenetic proteins, are pleiotropic cytokines that…”
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A modified pCas/pTargetF system for CRISPR-Cas9-assisted genome editing in Escherichia coli by Li, Qi, Sun, Bingbing, Chen, Jun, Zhang, Yiwen, Jiang, Yu, Yang, Sheng

“…Abstract The clustered regularly interspaced short palindromic repeats (CRISPR)-associated nuclease 9 (Cas9)-based genome editing tool pCas/pTargetF system…”
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Metformin induces ferroptosis by targeting miR-324-3p/GPX4 axis in breast cancer by Hou, Yifeng, Cai, Shuang, Yu, Shouyang, Lin, Hui

“…Abstract Metformin is a widely prescribed hypoglycemic drug. Many studies have shown its anti-cancer properties. In the present study, we aimed to explore the…”
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Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells by Saini, Nipun, Yang, Xiaohe

“…Abstract Metformin, a first line medication for type II diabetes, initially entered the spotlight as a promising anti-cancer agent due to epidemiologic reports…”
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Interaction between autophagy and the NLRP3 inflammasome by Cao, Zhenrui, Wang, Yanhao, Long, Zhimin, He, Guiqiong

“…Autophagy, a metabolic pathway that plays an important role in maintaining the dynamic balance of cells, has two types, i.e. non-selective autophagy and…”
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TBK1, a central kinase in innate immune sensing of nucleic acids and beyond by Zhou, Ruyuan, Zhang, Qian, Xu, Pinglong

“…Sensing of intracellular and extracellular environments is one of the fundamental processes of cell. Surveillance of aberrant nucleic acids, derived either…”
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Mesenchymal stem cell-derived exosomal miR-21a-5p promotes M2 macrophage polarization and reduces macrophage infiltration to attenuate atherosclerosis by Ma, Jian, Chen, Li, Zhu, Xiang, Li, Qing, Hu, Liqun, Li, Hongqi

“…Abstract Atherosclerosis (AS) is the main pathological basis for ischemic cardiovascular and cerebrovascular diseases. Mesenchymal stem cell (MSC)-derived…”
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Wnt/Ca2+ signaling pathway: a brief overview by De, Antara

“…The non-canonical Wnt/Ca2+ signaling cascade is less characterized than their canonical counterpart, the Wnt/β-catenin pathway. The non-canonical Wnt signaling…”
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Feedback regulation of TGF-β signaling by Yan, Xiaohua, Xiong, Xiangyang, Chen, Ye-Guang

“…Abstract Transforming growth factor beta (TGF-β) is a multi-functional polypeptide that plays a critical role in regulating a broad range of cellular functions…”
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Elevated G6PD expression contributes to migration and invasion of hepatocellular carcinoma cells by inducing epithelial-mesenchymal transition by Lu, Ming, Lu, Lu, Dong, Qiongzhu, Yu, Guangyang, Chen, Jinhong, Qin, Lunxiu, Wang, Lianxin, Zhu, Wenwei, Jia, Huliang

“…Abstract Altered metabolism is one of the hallmarks of cancer cells. Pentose phosphate pathway (PPP) is a fundamental component of cellular metabolism…”
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Exosomal LINC00355 derived from cancer-associated fibroblasts promotes bladder cancer cell resistance to cisplatin by regulating miR-34b-5p/ABCB1 axis by Luo, Guangyue, Zhang, Yangyang, Wu, Zhonghui, Zhang, Ligang, Liang, Chaozhao, Chen, Xianguo

“…Abstract Cisplatin resistance is a major challenge for bladder cancer (BC). Evidence indicates that exosome derived from cancer-associated fibroblasts…”
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Co-expression networks for plant biology: why and how by Rao, Xiaolan, Dixon, Richard A

“…Co-expression network analysis is one of the most powerful approaches for interpretation of large transcriptomic datasets. It enables characterization of…”
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Exosomal lncRNA FOXD3-AS1 upregulates ELAVL1 expression and activates PI3K/Akt pathway to enhance lung cancer cell proliferation, invasion, and 5-fluorouracil resistance by Mao, Guangxian, Mu, Zhimin, Wu, Da

“…Abstract Long non-coding RNA (lncRNA) FOXD3-AS1 expression is upregulated in lung cancer; however, its effect and mechanism on 5-fluorouracil (5-FU) resistance…”
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Fourier Transform Infrared Spectroscopic Analysis of Protein Secondary Structures by KONG, Jilie, YU, Shaoning

“…Infrared spectroscopy is one of the oldest and well established experimental techniques for the analysis of secondary structure of polypeptides and proteins…”
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Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells by Wu, Yingchao, Pi, Dajin, Zhou, Shuyao, Yi, Zhongjia, Dong, Yangyang, Wang, Wuhong, Ye, Huan, Chen, Yiliu, Zuo, Qian, Ouyang, Mingzi

“…Ginsenoside Rh3 (GRh3) is a seminatural product obtained by chemical processing after isolation from Chinese herbal medicine that has strong antitumor activity…”
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Piezo1 regulates migration and invasion of breast cancer cells via modulating cell mechanobiological properties by Yu, Yang, Wu, Xiao’an, Liu, Sisi, Zhao, Hongping, Li, Bo, Zhao, Hucheng, Feng, Xiqiao

“…Abstract Cell migration and invasion are two essential processes during cancer metastasis. Increasing evidence has shown that the Piezo1 channel is involved in…”
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