Search Results - "Acta Poloniae pharmaceutica"

Kinetic modeling on drug release from controlled drug delivery systems by Dash, Suvakanta, Murthy, Padala Narasimha, Nath, Lilakanta, Chowdhury, Prasanta

“…In this paper we review the mathematical models used to determine the kinetics of drug release from drug delivery systems. The quantitative analysis of the…”
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Paracetamol: mechanism of action, applications and safety concern by Jóźwiak-Bebenista, Marta, Nowak, Jerzy Z

“…Paracetamol/acetaminophen is one of the most popular and most commonly used analgesic and antipyretic drugs around the world, available without a prescription,…”
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PHARMACOLOGICAL ACTIVITIES OF PROTOCATECHUIC ACID by Khan, Abida Kalsoom, Rashid, Rehana, Fatima, Nighat, Mahmood, Sadaf, Mir, Sadullah, Khan, Sara, Jabeen, Nyla, Murtaza, Ghulam

“…Protocatechuic acid (3,4-dihydroxybenzoic acid, PCA) is a simple phenolic acid. It is found in a large variety of edible plants and possesses various…”
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Lipophilicity--methods of determination and its role in medicinal chemistry by Rutkowska, Ewelina, Pajak, Karolina, Jóźwiak, Krzysztof

“…Lipophilicity is a physicochemical property of crucial importance in medicinal chemistry. On the molecular level it encodes information on the network of…”
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Evaluation of the consumption of potentially goitrogenic food products in various models of plant-based diets in Poland by Kryczyk-Kozioł, Jadwiga, Zagrodzki, Paweł, Podsiadły, Robert, Galanty, Agnieszka, Paśko, Paweł

“…The aim of this study was to evaluate the consumption frequency of the selected examples of goitrogenic foods in four different groups of people in Poland, who…”
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Effects of zinc supplementation on metabolic status in patients with metabolic syndrome by Althanoon, Zeina, Merkhan, Marwan

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Atorvastatin can inhibit ovarian cancer by decreasing VEGF, TGF-β1 and increasing cytochrome-c and caspase-3 expressions by Chen, HongJu, Shi, HuaiJing, Jiang, XinYan

“…Objective: Atorvastatin (ATV), being widely utilized in clinical practice, is recognized as a prevalent cancer drug with established safety profiles. The…”
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CAR-T immunotherapy - recent advances and current challenges in cancer treatment: a review by Ronowicz-Pilarczyk, Joanna

“…Adoptive cell therapy represents a modern immunotherapeutic approach utilizing immune cells as dynamic agents against cancer cells, often called "living…”
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Raman spectroscopic imaging – practical applications in industrial pharmacy and medical diagnostics: a review by Ronowicz-Pilarczyk, Joanna

“…Currently, Raman imaging as a non-destructive technique providing knowledge on structural characterization of the investigated samples is gaining more and more…”
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Effect and mechanism of protease inhibitor oprozomib on doxorubicin sensitivity of hepatocellular carcinoma cells by Qi, Feng, Zheng, Sheng, Hou, Lu, Fu, XinNian, Wang, XinXin, Fu, ZhiPeng, Yang, Juan

“…This study was to examine the impact of Oprozomib (OPZ), an oral second-generation proteasome inhibitor, on the sensitivity of hepatocellular carcinoma (HCC)…”
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Novel Approach: Diphenhydramine and Lidocaine Combination Therapy for Alleviating Inflammatory and Allergic Skin Conditions with Coexisting Itch by Karłowicz-Bodalska, Katarzyna, Janicka, Natalia, Oślizło, Małgorzata, Sauer, Natalia Julia

“…Skin inflammatory and allergic conditions often result in symptoms such as erythema, edema, and pruritus, significantly impacting patients' quality of life…”
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Bioanalytical method validation for therapeutic drug monitoring of olaparib in patients with ovarian cancer by Lewandowski, Konrad, Karbownik, Agnieszka, Czyrski, Andrzej, Urjasz, Hanna, Stanisławiak-Rudowicz, Joanna, Grześkowiak, Edmund, Szałek, Edyta

“…Olaparib, an oral poly-ADP ribose polymerase (PARP) inhibitor, is a relatively new anticancer drug. It is essential to find TDM-guided dosage for better safety…”
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In vitro study of momordin Ic in improving atopic dermatitis by regulating claudin-1/MyD88 and targeting NLRP3 by Guo, Ying, Wang, Litao, Zhang, Jing, Jing, Tingting, Fu, Lefan, Miao, Guoying

“…Atopic dermatitis (AD) is a non-infectious inflammatory skin disease characterized by persistent itching of the skin, and it has become a global health problem…”
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Development and validation of analytical method for determination of elemental impurities in micafungin for injection by Ozlem Gundogdu, Sena, Turhan, Seda, Ozel Babacanoglu, Aynur, Catak, Tugce, Sahin, Adem

“…Elemental impurities contained in drug product create a risk for patients and potential toxic elemental impurities defined and classified in Guideline for…”
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HPLC-ESI-QTOF-MS/MS Analysis of Artemisia cina Leaves Aqueous Extract and Flavonoid Isolation Using High-speed Countercurrent Chromatography by Tshunungwa, Sonwabiso, Alsharif, Bashaer, Bekezhanova, Tolkyn, Begalinovna Bazhykova, Kulzada, Kukula-Koch, Wirginia, Boylan, Fabio

“…Artemisia cina Berg ex Poljakov, a shrubby plant endemic to the semi-arid areas of Kazakhstan, has as a long history of being used in traditional medicines as…”
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Application of dominance-based rough set approach in vaginal dosage forms optimization by Pałkowski, Łukasz, Karolak, Maciej, Kubiak, Bartłomiej, Błaszczyński, Jerzy, Słowiński, Roman

“…The objective of this study was to identify cause-effect relationships between various data related to vaginal dosage forms, such as composition, process…”
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Drug-drug interaction between pachymic acid and repaglinide in rats and its potential mechanism by Gu, Jing, Zhang, Hui, Li, Xinxin

“…Both repaglinide and pachymic acid are useful for reducing blood glucose, but the drug interactions between them are not known. This study aimed to explore the…”
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Vitamin C: Overview of drugs and dietary supplements and analytical methods for determining its content by Krukowski, Sylwester, Biały, Jakub, Adamczyk, Aleksandra, Kowalewska, Aleksandra

“…Vitamin C is one of the most well-known and most frequently used substances found in various pharmaceutical preparations. Patients consider it as a safe…”
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Monoterpenes as Medicinal Agents: Exploring the Pharmaceutical Potential of p-Cymene, p-Cymenene, and γ-Terpinene by Bagińska, Sylwia, Golonko, Aleksandra, Świsłocka, Renata, Lewandowski, Włodzimierz

“…This review highlights the therapeutic propeties of monoterpenes, particularly γ-terpinene, p-cymene, and p-cymenene, found in essential oils derived from…”
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Inhibition of Colon Cancer Xenograft Growth by Celecoxib Analog OSU-03013 Through Wnt/β-Catenin Pathway Modulation by Yang, ChunYong, Zhou, ZhiQiang, Tian, JiaXin, Jin, RuoTian, Li, ZhanYong

“…OSU-03013 is a Celecoxib analog that dose not inhibit COX-2 expression. OSU-03013 effectively mimics the anti-tumor effects of Celecoxib, however, its exact…”
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