Search Results - "Acosta, Javier"
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WikiPathways 2024: next generation pathway database
Published in Nucleic acids research (05-01-2024)“…Abstract WikiPathways (wikipathways.org) is an open-source biological pathway database. Collaboration and open science are pivotal to the success of…”
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New Ways of Supporting Arts Entrepreneurship: A Case Study of Maniobra
Published in Artivate (01-04-2023)“…This research analyses Maniobra, a cultural employment initiative that offers guaranteed income and additional support for three years to selected artists in…”
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Decolonising the cultural policy and management curriculum - reflections from practice
Published in Cultural trends (14-03-2024)“…Decolonising the curriculum is a global imperative that takes different forms and urgency depending on the context. Developments across the globe such as…”
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The Impact of Agricultural Credit on Banana cultivation in Valle del Cauca, Colombia
Published in Revista de ciencias agricolas (05-05-2023)“…This study aimed to explore the use and effect of agricultural credit disbursed from banks and financial institutions on banana yield in farmers from Valle del…”
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Artists Profiles: Maniobra
Published in Artivate (01-04-2023)“…Maniobra is a cultural employment initiative providing guaranteed income and additional support for artists and collectives in Puerto Rico over three years…”
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Rational Design of a Thermostable 2'-Deoxyribosyltransferase for Nelarabine Production by Prediction of Disulfide Bond Engineering Sites
Published in International journal of molecular sciences (05-10-2022)“…One of the major drawbacks of the industrial implementation of enzymatic processes is the low operational stability of the enzymes under tough industrial…”
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Designing cultural policy in a postcolonial colony: the case of Puerto Rico
Published in International journal of cultural policy : CP (04-05-2017)“…Puerto Rico became a territory of the United States in 1898 with the end of the Spanish-American War. In 1952, the island became a 'Commonwealth' through the…”
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Mitochondrial dysfunction in anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) immune-mediated necrotising myopathy
Published in Neuromuscular disorders : NMD (01-05-2022)“…•Several non-inflammatory mechanisms of cell stress, such as mitochondrial dysfunction, have been linked to the pathogenesis of IIM.•Our results show that…”
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Development and evaluation of specific polymerase chain reaction assays for detecting Theileria equi genotypes
Published in Parasites & vectors (25-11-2023)“…Theileria equi causes equine piroplasmosis, an economically significant disease that affects horses and other equids worldwide. Based on 18S ribosomal RNA (18S…”
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Engineering a Bifunctional Fusion Purine/Pyrimidine Nucleoside Phosphorylase for the Production of Nucleoside Analogs
Published in Biomolecules (Basel, Switzerland) (23-09-2024)“…Nucleoside phosphorylases (NPs) are pivotal enzymes in the salvage pathway, catalyzing the reversible phosphorolysis of nucleosides to produce nucleobases and…”
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Novel Directed Enzyme Prodrug Therapy for Cancer Treatment Based on 2'-Deoxyribosyltransferase-Conjugated Magnetic Nanoparticles
Published in Biomolecules (Basel, Switzerland) (24-07-2024)“…Directed enzyme prodrug therapy (DEPT) strategies show promise in mitigating chemotherapy side effects during cancer treatment. Among these, the use of…”
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Harmonising knowledge for safer materials via the “NanoCommons” Knowledge Base
Published in Frontiers in physics (13-11-2023)“…In mediaeval Europe, the term “commons” described the way that communities managed land that was held “in common” and provided a clear set of rules for how…”
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N-Ribosyltransferase From Archaeoglobus veneficus: A Novel Halotolerant and Thermostable Biocatalyst for the Synthesis of Purine Ribonucleoside Analogs
Published in Frontiers in bioengineering and biotechnology (16-06-2020)“…Nucleoside-2′-deoxyribosyl-transferases (NDTs) catalyze a transglycosylation reaction consisting of the exchange of the 2′-deoxyribose moiety between a purine…”
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Molecular Basis of NDT-Mediated Activation of Nucleoside-Based Prodrugs and Application in Suicide Gene Therapy
Published in Biomolecules (Basel, Switzerland) (18-01-2021)“…Herein we report the first proof for the application of type II 2'-deoxyribosyltransferase from ( NDT) in suicide gene therapy for cancer treatment. To this…”
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Severe Frostbite Due to Extreme Altitude Climbing in South America: A Case Report
Published in Curēus (Palo Alto, CA) (08-08-2022)“…Frostbite is a tissue injury secondary to freezing that can currently be categorized using two schemes (Cauchy and clinical scheme). However, we present a…”
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Hypoxanthine-Guanine Phosphoribosyltransferase/adenylate Kinase From Zobellia galactanivorans: A Bifunctional Catalyst for the Synthesis of Nucleoside-5′-Mono-, Di- and Triphosphates
Published in Frontiers in bioengineering and biotechnology (24-06-2020)“…In our search for novel biocatalysts for the synthesis of nucleic acid derivatives, we found a good candidate in a putative dual-domain hypoxanthine-guanine…”
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Regional moderate hyperthermia for mild-to-moderate COVID-19 (TherMoCoV study): a randomized controlled trial
Published in Frontiers in medicine (2023)“…BackgroundTo prevent COVID-19 progression, low-cost alternatives that are available to all patients are needed. Diverse forms of thermotherapy have been…”
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Medication adherence in schizophrenia
Published in World journal of psychiatry (22-10-2012)“…Non-adherence is a major problem in the treatment of schizophrenia. Its high prevalence, potentially severe consequences and associated costs make the study of…”
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Conocimiento y pensamiento práctico docente en Ángel I. Pérez Gómez
Published in Márgenes (Málaga) (30-09-2022)“…Este artículo es un recorrido por la obra de Ángel I. Pérez Gómez en donde se aborda la cuestión del conocimiento práctico y el pensamiento docente. Se extraen…”
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Effectiveness and cost-effectiveness of a multicomponent intervention to improve medication adherence in people with depressive disorders - MAPDep: a study protocol for a cluster randomized controlled trial
Published in Patient preference and adherence (01-01-2019)“…Depression is a widespread mental disorder which can be treated effectively. However, low adherence to antidepressants is very common. The study of medication…”
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