Search Results - "Ackrill, Andrew M."
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Peginterferon-α2a and ribavirin combination therapy in chronic hepatitis C: A randomized Study of Treatment duration and ribavirin dose
Published in Annals of internal medicine (02-03-2004)Get full text
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Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon α-2a (40 kd)/ribavirin therapy
Published in Hepatology (Baltimore, Md.) (01-05-2006)“…Approximately one third of hepatitis C virus (HCV) genotype 1 patients achieved a sustained virological response (SVR) after 24 weeks of treatment with…”
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Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon alpha-2a (40 kd)/ribavirin therapy
Published in Hepatology (Baltimore, Md.) (01-05-2006)“…Approximately one third of hepatitis C virus (HCV) genotype 1 patients achieved a sustained virological response (SVR) after 24 weeks of treatment with…”
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Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene
Published in Nucleic acids research (25-08-1991)“…Expression of the E1A oncogene of adenovirus type 5 inhibits the response of interferon (IFN)-inducible constructs to Type I (alpha,beta) and II (gamma) IFNs…”
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Optimized Virologic Response in Hepatitis C Virus Genotype 4 with Peginterferon-α2a and Ribavirin
Published in Annals of internal medicine (06-01-2004)Get full text
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Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response
Published in Gastroenterology (New York, N.Y. 1943) (01-11-1999)“…Background & Aims: Patients with chronic hepatitis C virus infection are commonly treated with interferon alfa (IFN-α), but the long-term response rate is…”
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Optimized virologic response in hepatitis C virus genotype 4 with peginterferon-alpha2a and ribavirin
Published in Annals of internal medicine (06-01-2004)Get full text
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Expression of the Terminal Protein Region of Hepatitis B Virus Inhibits Cellular Responses to Interferons α and γ and Double-Stranded RNA
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1991)“…Constructs expressing the core, surface, X, or polymerase proteins of hepatitis B virus were transfected into human cells. In transient assays, only the…”
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Selection of HCV NS5A quasispecies during IFN therapy in patients with chronic HCV
Published in Digestive diseases and sciences (01-07-2001)“…Interferon treatment of chronic hepatitis C virus infection is successful in a minority of patients. The sequence of the interferon sensitivity determining…”
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Transcription factors induced by interferons α and γ
Published in Nucleic acids research (25-11-1990)“…Factors induced by interferons (IFNs) bind to the IFN-stimulated response elements (ISREs) of many genes. In human cells treated with type I (alpha, beta) IFN,…”
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11
Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose
Published in Annals of internal medicine (02-03-2004)“…Treatment with pegylated interferon (peginterferon) and ribavirin for 48 weeks is more effective than conventional interferon and ribavirin in patients with…”
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Specific deletions in the hepatitis B virus core open reading frame in patients with chronic active hepatitis B
Published in Journal of medical virology (01-10-1993)“…The polymerase chain reaction (PCR) and DNA sequencing were used to examine genomic variation in the pre-core/core open reading frame of the hepatitis B virus…”
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Differential response of the human 6-16 and 9-27 genes to α and γ interferons
Published in Nucleic acids research (11-02-1991)“…9-27 mRNA is expressed to a high level in response to both alpha and gamma interferons. In contrast, 6-16 mRNA is expressed well in response to alpha but very…”
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Comparison of pre-core/core hepatitis B virus region in liver tissue and serum from patients with chronic hepatitis B infection
Published in Journal of hepatology (1992)“…We examined the relationship between HBV-DNA isolated from the liver and from the serum in patients with various serological characteristics of chronic…”
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Expression of hamster MHC class I antigens in transformed cells and tumours induced by human adenoviruses
Published in European journal of cancer & clinical oncology (01-11-1988)“…The steady-state levels of hamster MHC class I mRNA and cell surface protein were analysed in cells transformed by either adenovirus type 12 (Ad12) or types 2…”
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