Search Results - "Ackermann, Teresa F."

Akt2 Deficiency is Associated with Anxiety and Depressive Behavior in Mice by Leibrock, Christina, Ackermann, Teresa F., Hierlmeier, Michael, Lang, Florian, Borgwardt, Stefan, Lang, Undine E.

“…Background: The economic burden associated with major depressive disorder and anxiety disorders render both disorders the most common and debilitating…”
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Inhibition of Colonic Tumor Growth by the Selective SGK Inhibitor EMD638683 by Towhid, Syeda T., Liu, Gui-Lai, Ackermann, Teresa F., Beier, Norbert, Scholz, Wolfgang, Fuchß, Thomas, Toulany, Mahmoud, Rodemann, Hans-Peter, Lang, Florian

“…Background: The serum and glucocorticoid inducible kinase SGK1, which was originally cloned from mammary tumor cells, is highly expressed in some but not all…”
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Hyperaldosteronism in Klotho-deficient mice by Fischer, Stephanie S, Kempe, Daniela S, Leibrock, Christina B, Rexhepaj, Rexhep, Siraskar, Balasaheb, Boini, Krishna M, Ackermann, Teresa F, Föller, Michael, Hocher, Berthold, Rosenblatt, Kevin P, Kuro-O, Makoto, Lang, Florian

“…Klotho is a membrane protein participating in the inhibitory effect of FGF23 on the formation of 1,25-dihydroxyvitamin-D(3) [1,25(OH)(2)D(3)]. It participates…”
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Hyperactivity and Enhanced Curiosity of Mice Expressing PKB/SGK-resistant Glycogen Synthase Kinase-3 (GSK-3) by Ackermann, Teresa F., Kempe, Daniela S., Lang, Florian, Lang, Undine E.

“…Background: Mounting evidence suggests that bipolar disorder symptoms could be favorably influenced by modification of glycogen synthase kinase-3 (GSK-3)…”
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Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1 by Boini, Krishna M, Graf, Dirk, Hennige, Anita M, Koka, Saisudha, Kempe, Daniela S, Wang, Kan, Ackermann, Teresa F, Föller, Michael, Vallon, Volker, Pfeifer, Karl, Schleicher, Erwin, Ullrich, Susanne, Häring, Hans-Ulrich, Häussinger, Dieter, Lang, Florian

“…The pore-forming K+-channel alpha-subunit KCNQ1 is expressed in a wide variety of tissues including heart, skeletal muscle, liver, and epithelia. Most recent…”
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Relative resistance of SGK1 knockout mice against chemical carcinogenesis by Nasir, Omaima, Wang, Kan, Föller, Michael, Gu, Shuchen, Bhandaru, Madhuri, Ackermann, Teresa F., Boini, Krishna M., Mack, Andreas, Klingel, Karin, Amato, Rosario, Perrotti, Nicola, Kuhl, Dietmar, Behrens, Jürgen, Stournaras, Christos, Lang, Florian

“…The serum and glucocorticoid inducible kinase SGK1 was originally cloned from mammary tumor cells. SGK1 was found to be up‐regulated in a variety of tumors,…”
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Accelerated suicidal erythrocyte death in Klotho-deficient mice by Kempe, Daniela S., Ackermann, Teresa F., Fischer, Stephanie S., Koka, Saisudha, Boini, Krishna M., Mahmud, Hasan, Föller, Michael, Rosenblatt, Kevin P., Kuro-o, Makoto, Lang, Florian

“…Klotho, a membrane protein mainly expressed in parathyroid glands, kidney, and choroid plexus, counteracts aging and increases the life span. Accordingly, life…”
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SGK1-sensitive renal tubular glucose reabsorption in diabetes by Ackermann, Teresa F, Boini, Krishna M, Völkl, Harald, Bhandaru, Madhuri, Bareiss, Petra M, Just, Lothar, Vallon, Volker, Amann, Kerstin, Kuhl, Dietmar, Feng, Yuxi, Hammes, Hans-Peter, Lang, Florian

“…The hyperglycemia of diabetes mellitus increases the filtered glucose load beyond the maximal tubular transport rate and thus leads to glucosuria. Sustained…”
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Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs by Gulbins, Erich, Palmada, Monica, Reichel, Martin, Lüth, Anja, Böhmer, Christoph, Amato, Davide, Müller, Christian P, Tischbirek, Carsten H, Groemer, Teja W, Tabatabai, Ghazaleh, Becker, Katrin A, Tripal, Philipp, Staedtler, Sven, Ackermann, Teresa F, van Brederode, Johannes, Alzheimer, Christian, Weller, Michael, Lang, Undine E, Kleuser, Burkhard, Grassmé, Heike, Kornhuber, Johannes

“…Depression is a debilitating condition for which new treatments are sorely needed. Now, Erich Gulbins and his colleagues report that reducing ceramide levels…”
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EMD638683, a Novel SGK Inhibitor with Antihypertensive Potency by Ackermann, Teresa F., Boini, Krishna M., Beier, Norbert, Scholz, Wolfgang, Fuchß, Thomas, Lang, Florian

“…The serum- and glucocorticoid-inducible kinase 1 (SGK1) is transcriptionally upregulated by mineralocorticoids and activated by insulin. The kinase enhances…”
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Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 by Lang, Elisabeth, Bissinger, Rosi, Fajol, Abul, Salker, Madhuri S., Singh, Yogesh, Zelenak, Christine, Ghashghaeinia, Mehrdad, Gu, Shuchen, Jilani, Kashif, Lupescu, Adrian, Reyskens, Kathleen M. S. E., Ackermann, Teresa F., Föller, Michael, Schleicher, Erwin, Sheffield, William P., Arthur, J. Simon C., Lang, Florian, Qadri, Syed M.

“…The mitogen- and stress-activated kinase MSK1/2 plays a decisive role in apoptosis. In analogy to apoptosis of nucleated cells, suicidal erythrocyte death…”
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PKB/SGK-Resistant GSK3 Enhances Phosphaturia and Calciuria by FÖLLER, Michael, KEMPE, Daniela S, BHANDARU, Madhuri, ACKERMANN, Teresa F, JUDENHOFER, Martin S, PICHLER, Bernd J, BIBER, Jürg, WAGNER, Carsten A, LANG, Florian, BOINI, Krishna M, PATHARE, Ganesh, SIRASKAR, Balasaheb, CAPUANO, Paola, ALESUTAN, Loana, SOPJANI, Mentor, STRANGE, Gerti, MOHEBBI, Nilufar

“…Insulin and IGF1-dependent signaling activates protein kinase B and serum and glucocorticoid inducible kinase (PKB/SGK), which together phosphorylate and…”
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SGK1-dependent Intestinal Tumor Growth in APC-deficient Mice by Wang, Kan, Gu, Shuchen, Nasir, Omaima, Föller, Michael, Ackermann, Teresa F., Klingel, Karin, Kandolf, Reinhard, Kuhl, Dietmar, Stournaras, Christos, Lang, Florian

“…Adenomatous polyposis coli (APC) is inactivated in familial adenomatous polyposis and sporadic colorectal cancer. Mice carrying defective APC (apc Min/+ )…”
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Effects of Gum Arabic (Acacia senegal) on Renal Function in Diabetic Mice by Nasir, Omaima, Umbach, Anja T., Rexhepaj, Rexhep, Ackermann, Teresa F., Bhandaru, Madhuri, Ebrahim, Ammar, Artunc, Ferruh, Kempe, Daniela S., Puchchakayala, Goverdhan, Siraskar, Balasaheb, Föller, Michael, Saeed, Amal, Lang, Florian

“…Background/Aims: Gum arabic (GA) is a Ca 2+ -, Mg 2+ - and K + -rich dietary fiber used for the treatment of patients with chronic kidney disease in Middle…”
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Phosphatidylinositide Dependent Kinase Deficiency Increases Anxiety and Decreases GABA and Serotonin Abundance in the Amygdala by Ackermann, Teresa F., Hörtnagl, Heide, Wolfer, David P., Colacicco, Giovanni, Sohr, Reinhard, Lang, Florian, Hellweg, Rainer, Lang, Undine E.

“…Pathological anxiety is paralleled by deficits in serotonergic and GABAergic neurotransmission in the amygdala. Conversely, anxiety disorders and depression…”
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Downregulation of Angiogenin Transcript Levels and Inhibition of Colonic Carcinoma by Gum Arabic (Acacia senegal) by Nasir, Omaima, Wang, Kan, Foller, Michael, Bhandaru, Madhuri, Sandulache, Diana, Artunc, Ferruh, Ackermann, Teresa F, Ebrahim, Ammar, Palmada, Monica, Klingel, Karin, Saeed, Amal M, Lang, Florian

“…Gum Arabic (GA), a nutrient from dried exudate of Acacia senegal, is widely used as emulsifier and stabilizer. It stimulates sodium and water absorption in…”
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Phosphoinositide-Dependent Protein Kinase 1 (PDK1): Impact on Schizophrenia Risk and Endophenotype Profile by Lang, Undine E., Ackermann, Teresa F., Wolfer, David, Schubert, Florian, Sohr, Reinhard, Hörtnagl, Heide, Lang, Florian, Gallinat, Juergen

“…Phosphatidylinositol-3-kinase (PI3K) signaling influences susceptibility to virus infections, anoxia, obstetric complications, and cancer; which are changed in…”
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Tumor suppressor gene adenomatous polyposis coli downregulates intestinal transport by Rexhepaj, Rexhep, Rotte, Anand, Gu, Shuchen, Michael, Diana, Pasham, Venkanna, Wang, Kan, Kempe, Daniela S., Ackermann, Teresa F., Brücher, Björn, Fend, Falko, Föller, Michael, Lang, Florian

“…Loss of function mutations of the tumor suppressor gene adenomatous polyposis coli (APC) underly the familial adenomatous polyposis. Mice carrying an…”
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Regulation of renal tubular glucose reabsorption by Akt2/PKBβ by Kempe, Daniela S, Siraskar, Gulab, Fröhlich, Henning, Umbach, Anja T, Stübs, Michael, Weiss, Florian, Ackermann, Teresa F, Völkl, Harald, Birnbaum, Morris J, Pearce, David, Föller, Michael, Lang, Florian

“…Akt/PKB is known to regulate the facilitative glucose carrier GLUT4. Nothing is known, however, of the role of Akt/PKB in the regulation of renal epithelial…”
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Role of PDK1 in Regulation of Gastric Acid Secretion by Rotte, Anand, Bhandaru, Madhuri, Ackermann, Teresa F., Boini, Krishna M., Lang, Florian

“…Pharmacological inhibition of phosphoinositide 3-kinase (PI3K) has previously been shown to enhance basal gastric acid secretion. Signaling of PI-3-kinase…”
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