Search Results - "Acker, J.D."

Protease-activated Receptor-2 Exerts Contrasting Model-specific Effects on Acute Experimental Pancreatitis by Laukkarinen, Johanna M., Weiss, Eric R., van Acker, Gijs J.D., Steer, Michael L., Perides, George

“…Protease-activated receptor-2 (PAR2) is a 7-transmembrane G-protein-coupled tethered ligand receptor that is expressed by pancreatic acinar and ductal cells…”
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Experimental acute biliary pancreatitis induced by retrograde infusion of bile acids into the mouse pancreatic duct by Perides, George, Steer, Michael L, van Acker, Gijs JD, Laukkarinen, Johanna M

“…Mechanistic studies of acute pancreatitis require animal models because clinical material is generally not available during the early phases of the disease…”
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Age, Gender, and Hemispheric Differences in Human Striatum: A Quantitative Review and New Data from in Vivo MRI Morphometry by Raz, N., Torres, I.J., Acker, J.D.

“…We reviewed postmortem and neuroimaging studies of striatal neuroanatomy in humans. The quantitative review revealed evidence of moderate age-related shrinkage…”
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Tumor Progression Locus-2 Is a Critical Regulator of Pancreatic and Lung Inflammation during Acute Pancreatitis by Van Acker, Gijs J.D., Perides, George, Weiss, Eric R., Das, Santasabuj, Tsichlis, Philip N., Steer, Michael L.

“…Pancreatic and lung inflammation during acute pancreatitis is a poorly understood, but clinically important, phenomenon. The proto-oncogene Tpl2 (tumor…”
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Serine Protease Inhibitor Causes F-Actin Redistribution and Inhibition of Calcium-Mediated Secretion in Pancreatic Acini by Singh, Vijay P., Saluja, Ashok K., Bhagat, Lakshmi, Hietaranta, Antti J., Song, Albert, Mykoniatis, Andreas, Acker, Gijs J.D. Van, Steer, Michael L.

“…Background & Aims: The present study was undertaken to evaluate the role of serine proteases in regulating digestive enzyme secretion in pancreatic acinar…”
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Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment: The CAIRO4 Phase 3 Randomized Clinical Trial by van der Kruijssen, Dave E W, Elias, Sjoerd G, Vink, Geraldine R, van Rooijen, Karlijn L, 't Lam-Boer, Jorine, Mol, Linda, Punt, Cornelis J A, de Wilt, Johannes H W, Koopman, Miriam

“…The role of primary tumor resection (PTR) in synchronous patients with metastatic colorectal cancer (mCRC) who had unresectable metastases and few or absent…”
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Correlation of CT findings with intra-operative outcome in closed-loop small bowel obstruction (CL-SBO) by de Kok, Bente M., Toneman, Masja K., Oei, Stanley, Westerterp, Marinke, van Acker, Gijs J.D., van der Pool, Anne E.M., Zijta, Frank M., Bipat, Shandra

“…•Closed loop small bowel obstruction is a precursor for bowel wall ischemia and necrosis.•CT findings concerning mesenteric and bowel wall changes correlate…”
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Upfront resection versus no resection of the primary tumor in patients with synchronous metastatic colorectal cancer: the randomized phase III CAIRO4 study conducted by the Dutch Colorectal Cancer Group and the Danish Colorectal Cancer Group by van der Kruijssen, D E W, Elias, S G, van de Ven, P M, van Rooijen, K L, Lam-Boer, J 't, Mol, L, Punt, C J A, Sommeijer, D W, Tanis, P J, Nielsen, J D, Yilmaz, M K, van Riel, J M G H, Wasowiz-Kemps, D K, Loosveld, O J L, van der Schelling, G P, de Groot, J W B, van Westreenen, H L, Jakobsen, H L, Fromm, A L, Hamberg, P, Verseveld, M, Jaensch, C, Liposits, G I, van Duijvendijk, P, Oulad Hadj, J, van der Hoeven, J A B, Trajkovic, M, de Wilt, J H W, Koopman, M

“…Upfront primary tumor resection (PTR) has been associated with longer overall survival (OS) in patients with synchronous unresectable metastatic colorectal…”
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Antibiotic Duration After Laparoscopic Appendectomy for Acute Complicated Appendicitis by van Rossem, Charles C, Schreinemacher, Marc H F, van Geloven, Anna A W, Bemelman, Willem A

“…Optimal duration of antibiotic treatment to reduce infectious complications after an appendectomy for acute complicated appendicitis remains unclear. To…”
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Oncological Safety and Potential Cost Savings of Routine vs Selective Histopathological Examination After Appendectomy: Results of the Multicenter, Prospective, Cross-Sectional FANCY Study by Bastiaenen, Vivian P, de Jonge, Joske, Corten, Bartholomeus J G A, de Savornin Lohman, Elise A J, Kraima, Anne C, Swank, Hilko A, van Vliet, Jaap L P, van Acker, Gijs J D, van Geloven, Anna A W, In 't Hof, Klaas H, Koens, Lianne, de Reuver, Philip R, van Rossem, Charles C, Slooter, Gerrit D, Tanis, Pieter J, Terpstra, Valeska, Dijkgraaf, Marcel G W, Bemelman, Willem A

“…To investigate the oncological safety and potential cost savings of selective histopathological examination after appendectomy. The necessity of routine…”
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Safety and economic analysis of selective histopathology following cholecystectomy: multicentre, prospective, cross-sectional FANCY study by Bastiaenen, Vivian P, van Vliet, Jaap L P, de Savornin Lohman, Elise A J, Corten, Bartholomeus J G A, de Jonge, Joske, Kraima, Anne C, Swank, Hilko A, van Acker, Gijs J D, van Geloven, Anna A W, In 't Hof, Klaas H, Koens, Lianne, de Reuver, Philip R, van Rossem, Charles C, Slooter, Gerrit D, Tanis, Pieter J, Terpstra, Valeska, Dijkgraaf, Marcel G W, Bemelman, Willem A

“…There is ongoing debate concerning the necessity of routine histopathological examination following cholecystectomy. In order to reduce the pathology workload…”
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Technical Perspective for Video Based Assessment of Surgeries in Low-Resource Settings by van Kesteren, Jurre, van Goudoever, Leandra A.E., Conteh, Amara, van Acker, Gijs J.D., Bonjer, H. Jaap, Bolkan, Håkon A.

“…•Use of surgical training videos in low- and middle-income countries is limited•Chronological steps for shooting a surgical procedure in a low-resource…”
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A Population-Based Cohort Study on Efficacy and Safety of Bariatric Surgery in Young Adults Versus Adults by van de Pas, Kelly G. H., Esfandiyari Noushi, Aliyar, Janssen, Loes, Vreugdenhil, Anita C. E., Leclercq, Wouter K. G., van Dielen, François M. H.

“…Purpose Bariatric surgery is the most effective treatment for severe obesity in adults and has shown promising results in young adults. Lack of insight…”
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Does livestreaming surgical education have the future? Development and participant evaluation of a national COVID-19 livestreaming initiative by Feenstra, Tim M., van Felius, L. Peter, Vriens, Menno R., Stassen, Laurents P. S., van Acker, Gijs J. D., van Dijkum, Els J. M. Nieveen, Schijven, Marlies P., Bonjer, H. Jaap

“…Backgrounds COVID-19 related reduction of surgical procedures jeopardizes learning on the job of surgical residents. Many educators resorted to digital…”
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Management of resectable esophageal and gastric (mixed adeno)neuroendocrine carcinoma: A nationwide cohort study by van der Veen, A., Seesing, M.F.J., Wijnhoven, B.P.L., de Steur, W.O., van Berge Henegouwen, M.I., Rosman, C., van Sandick, J.W., Mook, S., Haj Mohammad, N., Ruurda, J.P., Brosens, L.A.A., van Hillegersberg, R., Alderlieste, Y.A., Baas, P.C., Belt, E.J.T., Ünlü, C., de Waard, J.W.D., Duijvendijk, P., Heisterkamp, J., Kouwenhoven, E.A., Nieuwenhuijzen, G.A.P., Pierik, E.G.J.M., Plukker, J.T.M., Pronk, A., Rijken, A.M., Scheepers, J.J.G., Stoot, J.H., Tetteroo, G.W.M., van Acker, G.J.D., van der Harst, E., van der Peet, D.L.

“…The aim of this study is to provide insight in accuracy of diagnosing, current treatment and survival in patients with resectable esophageal and gastric…”
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A mouse model of acute biliary pancreatitis induced by retrograde pancreatic duct infusion of Na-taurocholate by Laukkarinen, Johanna M, Van Acker, Gijs J D, Weiss, Eric R, Steer, Michael L, Perides, George

“…Objective:Most mechanistic studies of pancreatitis in mice employ the secretagogue-induced model. The currently reported studies were designed to develop an…”
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Safety and cost analysis of selective histopathological examination following appendicectomy and cholecystectomy (FANCY study): protocol and statistical analysis plan of a prospective observational multicentre study by Bastiaenen, Vivian P, Corten, Bartholomeus JGA, de Savornin Lohman, Elise AJ, de Jonge, Joske, Kraima, Anne C, Swank, Hilko A, van Vliet, Jaap LP, van Acker, Gijs JD, van Geloven, Anna AW, in 't Hof, Klaas H, Koens, Lianne, de Reuver, Philip R, van Rossem, Charles C, Slooter, Gerrit D, Tanis, Pieter J, Terpstra, Valeska, Dijkgraaf, Marcel GW, Bemelman, Willem A

“…IntroductionRoutine histopathological examination following appendicectomy and cholecystectomy has significant financial implications and comprises a…”
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Cause-effect relationships between zymogen activation and other early events in secretagogue-induced acute pancreatitis by Van Acker, Gijs J D, Weiss, Eric, Steer, Michael L, Perides, George

“…We have hypothesized that the colocalization of digestive zymogens with lysosomal hydrolases, which occurs during the early stages of every experimental…”
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Co-localization hypothesis： A mechanism for the intrapancreatic activation of digestive enzymes during the early phases of acute pancreatitis by van Acker, Gijs J D, Perides, George, Steer, Michael L

“…Acute pancreatitis is generally believed to be a disease in which the pancreas is injured by digestive enzymes that it normally produces. Most of the…”
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Alternative specimen extraction techniques after laparoscopic emergency colectomy in inflammatory bowel disease by Gardenbroek, Tjibbe J., Eshuis, Emma J., van Acker, Gijs J. D., Tanis, Pieter J., Bemelman, Willem A.

“…Background Omitting the extraction site incision potentially further decreases the abdominal wall trauma in laparoscopic surgery. The purpose of this study was…”
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