Search Results - "Ackah, Ezekiel Bonwin"
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Iron stores in steady‐state sickle cell disease children accessing care at a sickle cell disease clinic in Kumasi, Ghana: A cross‐sectional study
Published in Health science reports (01-11-2022)“…Background and Aims Children with sickle cell disease (SCD) have an increased risk of multiple hemotransfusions and this can predispose them to elevated iron…”
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Effects of COVID-19 disease on PAI-1 antigen and haematological parameters during disease management: A prospective cross-sectional study in a regional Hospital in Ghana
Published in PLOS global public health (2023)“…Individuals with COVID-19 experience thrombotic events probably due to the associated hypofibrinolysis resulting from the upregulation of plasminogen activator…”
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Hemopexin deficiency promotes acute kidney injury in sickle cell disease
Published in Blood (26-03-2020)“…Acute kidney injury (AKI) is a major clinical concern in sickle cell disease (SCD). Clinical evidence suggests that red cell alarmins may cause AKI in SCD,…”
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Enhanced Renal Clearance of Heme Triggers Acute Kidney Injury in Sickle Cell Disease
Published in Blood (08-12-2017)“…Circulating heme is scavenged primarily by hemopexin (Hx) for degradation in the liver, while alpha-1-microglobulin (A1M) binds heme for urinary clearance…”
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PA-500 Prevalence and genomic characterization of typhoidal and non-typhoidal Salmonellae in Ghana
Published in BMJ global health (17-12-2023)“…BackgroundSalmonella are a group of facultative anaerobic bacteria that belong to the family of Enterobacteriaceae. The common serovars are Salmonella enterica…”
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Organ damage in sickle cell disease study (ORDISS): protocol for a longitudinal cohort study based in Ghana
Published in BMJ open (01-08-2017)“…IntroductionSickle cell disease is highly prevalent in Africa with a significant public health burden. Nonetheless, morbidity and mortality in sickle cell…”
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