Search Results - "Achar, Sooraj R."

β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway by Ghosh, Sourish, Dellibovi-Ragheb, Teegan A., Kerviel, Adeline, Pak, Eowyn, Qiu, Qi, Fisher, Matthew, Takvorian, Peter M., Bleck, Christopher, Hsu, Victor W., Fehr, Anthony R., Perlman, Stanley, Achar, Sooraj R., Straus, Marco R., Whittaker, Gary R., de Haan, Cornelis A.M., Kehrl, John, Altan-Bonnet, Grégoire, Altan-Bonnet, Nihal

“…β-Coronaviruses are a family of positive-strand enveloped RNA viruses that includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is…”
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Universal antigen encoding of T cell activation from high-dimensional cytokine dynamics by Achar, Sooraj R, Bourassa, François X P, Rademaker, Thomas J, Lee, Angela, Kondo, Taisuke, Salazar-Cavazos, Emanuel, Davies, John S, Taylor, Naomi, François, Paul, Altan-Bonnet, Grégoire

“…Systems immunology lacks a framework with which to derive theoretical understanding from high-dimensional datasets. We combined a robotic platform with machine…”
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1317-A Analyzing the immunological variability in T cell/tumor interactions to identify a subpopulation of CD8+ T cells (Spark T cells) that drives successful cancer immunotherapy by Cavazos, Emanuel Salazar, Jia, Dongya, Kenet, Adam, Dada, Hannah, Achar, Sooraj R, Altan-Bonnet, Grégoire

“…BackgroundThousands of patients have benefited from the growing use of cancer immunotherapies. However, the success of these therapies can be highly variable…”
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Abstract LB103: Novel DNA-based-T-cell-activation for the generation of chimeric antigen receptor T cells with enhanced anti-leukemia cytotoxicity by Benzaoui, Mehdi, Achar, Sooraj R., Keskar, Vandana, Sood, Anup, Davis, Brian M., Highfill, Steven L., Altan-Bonnet, Grégoire, Chien, Christopher D., Taylor, Naomi

“…Abstract Chimeric antigen receptor (CAR)-T cell therapy has shown remarkable results in the treatment of hematological malignancies. However, several…”
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