Search Results - "Achaiah, G."

Molecular modeling studies of phenoxypyrimidinyl imidazoles as p38 kinase inhibitors using QSAR and docking by Ravindra, G.K., Achaiah, G., Sastry, G.N.

“…p38 Kinase plays a vital role in inflammation mediated by tumor necrosis factor-α (TNFα) and interleukin-1β (IL-1β) pathways and inhibitors of p38 kinase…”
Get full text

Multidrug Resistance Reversal Activity of Some New Dihydropyridines Studied by IN SITU Single-Pass Intestinal Perfusion (SPIP) Method in Rat by Sirisha, K., Achaiah, G., Prasad, N., Bhasker, S., Umachander, L., Malla Reddy, V.

“…P-glycoprotein (P-gp) mediated efflux affects the pharmacokinetics of several drugs. By analogy to verapamil, 1,4-dihydropyridines (DHPs) have been widely…”
Get full text

Novel targets for antiinflammatory and antiarthritic agents by Kulkarni, R G, Achaiah, G, Sastry, G Narahari

“…Inflammation is a complex pathological condition associated with exaggerated human immune system involving various activated immune cells and bio-molecules…”
Get more information

Design, synthesis and evaluation of new 2,6-dihydroimidazo[1,2-c]pyrimido[5,4-e]-pyrimidine-5(3H)-thiones as possible antihistaminic/antiasthmatic agents by Sirisha, K, Achaiah, G, Ram Rao, A

“…A series of new 10-(alkylamino)-8-methyl-2,6-dihydroimidazo[1,2-c]pyrimido[5,4-e]pyrimidine-5(3H)-thiones (4a-g) were subjected to molecular property…”
Get full text

Synthesis and Pharmacological Evaluation of (6-Substituted 4-Oxo-4H-chromene-3 yl) methyl N-substituted Aminoacetates by Gajbhiye, Asmita, Mallareddy, V, Achaiah, G

“…A series of the title compounds were synthesized and characterized by spectral data. All the compounds were evaluated for in vitro antihistaminic activity by…”
Get full text

Quaternary salts of 4,3′ and 4,4′ bis-pyridinium monooximes. Part 2: Synthesis and biological activity by Srinivas Rao, Chennamaneni, Venkateswarlu, Vobalaboina, Achaiah, Garlapati

“…In continuation of our investigations of unsymmetrical bisquaternary monooximes, we synthesized four new series of compounds bridged by hexyl, heptyl, octyl…”
Get full text