Search Results - "Accardi, Fabrizio"

Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma by Bae, Jooeun, Accardi, Fabrizio, Hideshima, Teru, Tai, Yu-Tzu, Prabhala, Rao, Shambley, Aaron, Wen, Kenneth, Rowell, Sean, Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.

“…Immune profiling in patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and multiple myeloma (MM)…”
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Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target by Bolzoni, Marina, Chiu, Martina, Accardi, Fabrizio, Vescovini, Rosanna, Airoldi, Irma, Storti, Paola, Todoerti, Katia, Agnelli, Luca, Missale, Gabriele, Andreoli, Roberta, Bianchi, Massimiliano G., Allegri, Manfredi, Barilli, Amelia, Nicolini, Francesco, Cavalli, Albertina, Costa, Federica, Marchica, Valentina, Toscani, Denise, Mancini, Cristina, Martella, Eugenia, Dall'Asta, Valeria, Donofrio, Gaetano, Aversa, Franco, Bussolati, Ovidio, Giuliani, Nicola

“…The importance of glutamine (Gln) metabolism in multiple myeloma (MM) cells and its potential role as a therapeutic target are still unknown, although it has…”
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Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling by Aversa, Franco, Dalla Palma, Benedetta, Bolzoni, Marina, Toscani, Denise, Accardi, Fabrizio, Giuliani, Nicola

“…Multiple myeloma (MM) is characterized by a high capacity to induce alterations in the bone remodeling process. The increase in osteoclastogenesis and the…”
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The Proteasome and Myeloma-Associated Bone Disease by Accardi, Fabrizio, Toscani, Denise, Costa, Federica, Aversa, Franco, Giuliani, Nicola

“…Bone disease is the hallmark of multiple myeloma (MM), a hematological malignancy characterized by osteolytic lesions due to a severe uncoupled and unbalanced…”
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The Proteasome Inhibitor Bortezomib Maintains Osteocyte Viability in Multiple Myeloma Patients by Reducing Both Apoptosis and Autophagy: A New Function for Proteasome Inhibitors by Toscani, Denise, Palumbo, Carla, Dalla Palma, Benedetta, Ferretti, Marzia, Bolzoni, Marina, Marchica, Valentina, Sena, Paola, Martella, Eugenia, Mancini, Cristina, Ferri, Valentina, Costa, Federica, Accardi, Fabrizio, Craviotto, Luisa, Aversa, Franco, Giuliani, Nicola

“…ABSTRACT Multiple myeloma (MM) is characterized by severely imbalanced bone remodeling. In this study, we investigated the potential effect of proteasome…”
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Impact of daratumumab/bortezomib/thalidomide and dexamethasone induction therapy on chemo-free stem cell mobilization in transplant eligible newly diagnosed multiple myeloma: a multicentre real-world experience by Porrazzo, Marika, Moscato, Tiziana, Sapienza, Giuseppe, Accardi, Fabrizio, Patti, Caterina, Cangialosi, Clotilde, Costanza, Carmelo, Bono, Roberto, Tringali, Stefania, Rotolo, Cristina, Gigliotta, Emilia, Rizzuto, Andrea, Ingrascè, Manuela Giuseppa, Butera, Giulia, Di Noto, Laura, Santoro, Alessandra, Marfia, Anna, Botta, Cirino, Siragusa, Sergio, Martino, Massimo, Castagna, Luca

“…Not available.Not available…”
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CD38 expression by plasma cells in extramedullary multiple myeloma by Notarfranchi, Laura, Accardi, Fabrizio, Mancini, Cristina, Martella, Eugenia, Bonomini, Sabrina, Segreto, Roberta, Vescovini, Rosanna, Palma, Anna Benedetta Dalla, Sammarelli, Gabriella, Todaro, Giannalisa, Storti, Paola, Burroughs-Garcia, Jessica, Iannozzi, Nicolas Thomas, Raimondi, Vincenzo, Lungu, Oxana, Ricci, Stefania, Craviotto, Luisa, Giuliani, Nicola

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The transcriptomic profile of CD138 + cells from patients with early progression from smoldering to active multiple myeloma remains substantially unchanged by Storti, Paola, Agnelli, Luca, Palma, Benedetta Dalla, Todoerti, Katia, Marchica, Valentina, Accardi, Fabrizio, Sammarelli, Gabriella, Deluca, Federica, Toscani, Denise, Costa, Federica, Vicario, Emanuela, Todaro, Giannalisa, Martella, Eugenia, Neri, Antonino, Giuliani, Nicola

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IL21R expressing CD14 + CD16 + monocytes expand in multiple myeloma patients leading to increased osteoclasts by Bolzoni, Marina, Ronchetti, Domenica, Storti, Paola, Donofrio, Gaetano, Marchica, Valentina, Costa, Federica, Agnelli, Luca, Toscani, Denise, Vescovini, Rosanna, Todoerti, Katia, Bonomini, Sabrina, Sammarelli, Gabriella, Vecchi, Andrea, Guasco, Daniela, Accardi, Fabrizio, Palma, Benedetta Dalla, Gamberi, Barbara, Ferrari, Carlo, Neri, Antonino, Aversa, Franco, Giuliani, Nicola

“…Bone marrow monocytes are primarily committed to osteoclast formation. It is, however, unknown whether potential primary alterations are specifically present…”
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Multiple Myeloma in 2023 Ways: From Trials to Real Life by Fazio, Manlio, Del Fabro, Vittorio, Parrinello, Nunziatina Laura, Allegra, Alessandro, Markovic, Uroš, Botta, Cirino, Accardi, Fabrizio, Vincelli, Iolanda Donatella, Leotta, Salvatore, Elia, Federica, Esposito, Benedetta, Garibaldi, Bruno, Sapuppo, Gabriele, Orofino, Alessandra, Romano, Alessandra, Palumbo, Giuseppe A, Di Raimondo, Francesco, Conticello, Concetta

“…Multiple myeloma is a chronic hematologic malignancy that obstinately tends to relapse. Basic research has made giant strides in better characterizing the…”
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Cutaneous localization in multiple myeloma in the context of bortezomib-based treatment: how do myeloma cells escape from the bone marrow to the skin? by Marchica, Valentina, Accardi, Fabrizio, Storti, Paola, Mancini, Cristina, Martella, Eugenia, Dalla Palma, Benedetta, Bolzoni, Marina, Todoerti, Katia, Marcatti, Magda, Schifano, Chiara, Bonomini, Sabrina, Sammarelli, Gabriella, Neri, Antonino, Ponzoni, Maurilio, Aversa, Franco, Giuliani, Nicola

“…The skin is a possible site of extramedullary localization in multiple myeloma (MM) patients; however, the mechanisms involved in this process are poorly…”
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Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties by Costa, Federica, Vescovini, Rosanna, Bolzoni, Marina, Marchica, Valentina, Storti, Paola, Toscani, Denise, Accardi, Fabrizio, Notarfranchi, Laura, Dalla Palma, Benedetta, Manferdini, Cristina, Manni, Sabrina, Todaro, Giannalisa, Lisignoli, Gina, Piazza, Francesco, Aversa, Franco, Giuliani, Nicola

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A Rare Case of Systemic AL Amyloidosis with Muscle Involvement: A Misleading Diagnosis by Notarfranchi, Laura, Aversa, Franco, Pietrini, Vladimiro, Cenacchi, Giovanna, Giuliani, Nicola, Costa, Roberta, Martella, Eugenia, Mancini, Cristina, Verga, Laura, Capello, Gian Luca, Capozzi, Anna Rita, Papa, Valentina, Accardi, Fabrizio, Dalla Palma, Benedetta

“…Muscle involvement in AL amyloidosis is a rare condition, and the diagnosis of amyloid myopathy is often delayed and underdiagnosed. Amyloid myopathy may be…”
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Neurofibromatosis type I and multiple myeloma coexistence: A possible link? by Accardi, Fabrizio, Marchica, Valentina, Mancini, Cristina, Maredi, Elena, Racano, Costantina, Notarfranchi, Laura, Martorana, Davide, Storti, Paola, Martella, Eugenia, Palma, Benedetta Dalla, Craviotto, Luisa, Filippo, Massimo De, Percesepe, Antonio, Aversa, Franco, Giuliani, Nicola

“…The association between Neurofibromatosis type I (NF1) and multiple myeloma (MM), a plasma cell, dyscrasia is very rare. Here we put to the attention of the…”
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The osteoblastic niche in the context of multiple myeloma by Toscani, Denise, Bolzoni, Marina, Accardi, Fabrizio, Aversa, Franco, Giuliani, Nicola

“…The osteoblastic niche has a critical role in the regulation of hemopoietic stem cell (HSC) quiescence and self‐renewal and in the support of hematopoiesis…”
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Combining bortezomib to high dose melphalan as conditioning regimen results in the improvement of the response rate in newly diagnosed young multiple myeloma patients by Dalla Palma, Benedetta, Accardi, Fabrizio, Prezioso, Lucia, Notarfranchi, Laura, Giuliani, Nicola

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Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation by Costa, Federica, Toscani, Denise, Chillemi, Antonella, Quarona, Valeria, Bolzoni, Marina, Marchica, Valentina, Vescovini, Rosanna, Mancini, Cristina, Martella, Eugenia, Campanini, Nicoletta, Schifano, Chiara, Bonomini, Sabrina, Accardi, Fabrizio, Horenstein, Alberto L, Aversa, Franco, Malavasi, Fabio, Giuliani, Nicola

“…It is known that multiple myeloma (MM) cells express CD38 and that a recently developed human anti-CD38 monoclonal antibody Daratumumab mediates myeloma…”
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Novel targets for the treatment of relapsing multiple myeloma by Giuliani, Nicola, Accardi, Fabrizio, Marchica, Valentina, Dalla Palma, Benedetta, Storti, Paola, Toscani, Denise, Vicario, Emanuela, Malavasi, Fabio

“…: Multiple myeloma (MM) is characterized by the high tendency to relapse and develop drug resistance. : This review focused on the main novel targets…”
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Short-Term Risk of Progression of Patients with Asymptomatic Monoclonal Gammopathies to Active Multiple Myeloma: The Critical Impact of the Tumoral Mass by Dalla Palma, Anna Benedetta, Notarfranchi, Laura, Crosara, Jessica, Pedrazzoni, Mario, Accardi, Fabrizio, Marchica, Valentina, Toscani, Denise, Vicario, Emanuela, Storti, Paola, Giuliani, Nicola

“…The identification of risk factors for progression is critical in the clinical management and appropriate follow up of patients with pre-malignant Asymptomatic…”
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P-360 Impact of Daratumumab/Bortezomib/Thalidomide/Dexamethasone (DVTD) Induction Therapy on Chemo-Free Stem Cell Mobilization in Newly Diagnosed Multiple Myeloma Patients: A Real Life Experience by Porrazzo, Marika, Moscato, Tiziana, Sapienza, Giuseppe, Accardi, Fabrizio, Patti, Caterina, Cangialosi, Clotilde, Bono, Roberto, Tringali, Stefania, Rotolo, Cristina, Noto, Laura Di, Santoro, Alessandra, Marfia, Anna, Martino, Massimo, Castagna, Luca

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