Search Results - "Acaz‐Fonseca, Estefanía"
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Insight into the molecular sex dimorphism of ischaemic stroke in rat cerebral cortex: Focus on neuroglobin, sex steroids and autophagy
Published in The European journal of neuroscience (01-07-2020)“…Including sex is of paramount importance in preclinical and clinical stroke researches, and molecular studies dealing in depth with sex differences in stroke…”
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Developmental Sex Differences in the Metabolism of Cardiolipin in Mouse Cerebral Cortex Mitochondria
Published in Scientific reports (06-03-2017)“…Cardiolipin (CL) is a mitochondrial-specific phospholipid. CL content and acyl chain composition are crucial for energy production. Given that estradiol…”
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Molecular mechanisms involved in the regulation of neuritogenesis by estradiol: Recent advances
Published in The Journal of steroid biochemistry and molecular biology (01-08-2012)“…This review analyzes the signaling mechanisms activated by estradiol to regulate neuritogenesis in several neuronal populations. Estradiol regulates axogenesis…”
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Sex differences in glia reactivity after cortical brain injury
Published in Glia (01-11-2015)“…Several brain disorders associated with neuroinflammation show sex differences in their incidence, onset, progression and/or outcome. The different regulation…”
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5
Gonadal hormones and the control of reactive gliosis
Published in Hormones and behavior (01-02-2013)“…This article is part of a Special Issue "Hormones & Neurotrauma". Astrocytes and microglia respond to central nervous system (CNS) injury with changes in…”
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Sex differences and gonadal hormone regulation of brain cardiolipin, a key mitochondrial phospholipid
Published in Journal of neuroendocrinology (01-01-2020)“…Cardiolipin (CL) is a phospholipid that is almost exclusively located in the inner mitochondrial membrane of eukaryotic cells. As a result of its unique…”
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Sex differences in the inflammatory response of primary astrocytes to lipopolysaccharide
Published in Biology of sex differences (11-07-2011)“…Numerous neurological and psychiatric disorders show sex differences in incidence, age of onset, symptomatology or outcome. Astrocytes, one of the glial cell…”
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Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficit
Published in PloS one (03-06-2015)“…Traumatic brain injury (TBI) incidence rises during adolescence because during this critical neurodevelopmental period some risky behaviors increase. The…”
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Notch signaling in astrocytes mediates their morphological response to an inflammatory challenge
Published in Cell death discovery (03-04-2019)“…In the nervous system, Notch pathway has a prominent role in the control of neuronal morphology and in the determination of the astrocyte fate. However, the…”
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Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions
Published in Progress in neurobiology (01-09-2016)“…In the last years there has been a considerable advance in the knowledge on the regulation of astrocytes by sex steroids under physiological and pathological…”
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A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 in neurons
Published in PloS one (30-01-2013)“…Neurogenin 3 (Ngn3), a proneural gene, regulates dendritogenesis and synaptogenesis in mouse hippocampal neurons. Ngn3 is transiently exported from the cell…”
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Role of astrocytes in the neuroprotective actions of 17β-estradiol and selective estrogen receptor modulators
Published in Molecular and cellular endocrinology (25-05-2014)“…•Estradiol regulates reactive astrogliosis and the inflammatory response of astrocytes.•Estradiol regulates neuroglobin expression in astrocytes.•Estradiol…”
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Lipotoxic Effects of Palmitic Acid on Astrocytes Are Associated with Autophagy Impairment
Published in Molecular neurobiology (01-03-2019)“…Obesity is associated with an increase in the brain levels of saturated free fatty acids, such as palmitic acid (PA). Previous studies have shown that PA…”
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14
Estradiol meets notch signaling in developing neurons
Published in Frontiers in endocrinology (Lausanne) (2011)“…The transmembrane receptor Notch, a master developmental regulator, controls gliogenesis, neurogenesis, and neurite development in the nervous system…”
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Profiling Neuroactive Steroid Levels After Traumatic Brain Injury in Male Mice
Published in Endocrinology (Philadelphia) (01-10-2016)“…The incidence of traumatic brain injuries (TBIs) in humans has rapidly increased in the last ten years. The most common causes are falls and car accidents…”
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Correlation of brain levels of progesterone and dehydroepiandrosterone with neurological recovery after traumatic brain injury in female mice
Published in Psychoneuroendocrinology (01-06-2015)“…Highlights • Neuroactive steroid levels change in the brain after TBI. • Brain and plasma steroid levels vary differently and independently after TBI. • Brain…”
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Sex Differences and Effects of Estrogenic Compounds on the Expression of Inflammatory Molecules by Astrocytes Exposed to the Insecticide Dimethoate
Published in Neurotoxicity research (01-04-2014)“…A low dose of the organophosphorus insecticide dimethoate (DMT) produces oxidation of lipids and proteins and impairs mitochondrial function in the brain of…”
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The Selective Estrogen Receptor Modulator Raloxifene Regulates Arginine-Vasopressin Gene Expression in Human Female Neuroblastoma Cells Through G Protein-Coupled Estrogen Receptor and ERK Signaling
Published in Endocrinology (Philadelphia) (01-10-2015)“…The selective estrogen receptor modulator raloxifene reduces blood pressure in hypertensive postmenopausal women. In the present study we have explored whether…”
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Estradiol and Testosterone Regulate Arginine-Vasopressin Expression in SH-SY5Y Human Female Neuroblastoma Cells Through Estrogen Receptors-α and -β
Published in Endocrinology (Philadelphia) (01-06-2013)“…The expression of arginine-vasopressin (AVP) is regulated by estradiol and testosterone (T) in different neuronal populations by mechanisms that are not yet…”
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CB2 cannabinoid receptor is involved in the anti-inflammatory effects of leptin in a model of traumatic brain injury
Published in Experimental neurology (01-05-2016)“…The rates for traumatic brain injury (TBI) have risen in the last decade. Studies in animal models and clinical trials have not yet resulted in an effective…”
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