Search Results - "Abuzinadah, Mohammed"
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Ursolic acid rich Ocimum sanctum L leaf extract loaded nanostructured lipid carriers ameliorate adjuvant induced arthritis in rats by inhibition of COX-1, COX-2, TNF-α and IL-1: Pharmacological and docking studies
Published in PloS one (20-03-2018)“…Ursolic acid (UA) is a promising molecule with anti-inflammatory, analgesic and potential anti-arthritic activity. This study was undertaken to make…”
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Pharmacological studies on the efficacy of a thymoquinone‐containing novel polyherbal formulation against cisplatin‐induced hepatorenal toxicity in rats
Published in Journal of food biochemistry (01-02-2020)“…The aim of this study was to investigate the protective effect of a novel polyherbal formulation against cisplatin‐induced hepatorenal toxicity in six groups…”
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The metabolic landscape of the bacteria Rhodococcus erythropolis used in the biodesulfurization of petroleum products: an emphasis on 2-hydroxybiphenyl
Published in Archives of microbiology (01-07-2024)“…Microorganisms produce diverse classes of metabolites under various physiological conditions. Many bacterial strains have been reported to carry out the…”
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Thiamin Regresses the Anticancer Efficacy of Methotrexate in the Amelioration of Diethyl Nitrosamine-Induced Hepatocellular Carcinoma in Wistar Strain Rats
Published in Nutrition and cancer (02-01-2020)“…Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer and occurs frequently in patients with liver cirrhosis. HCC is the leading…”
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Putative Anti-Cancer Drug Candidate Targeting the 'PLK-1-Polo-Box Domain' by High Throughput Virtual Screening: A Computational Drug Design Study
Published in Critical reviews in eukaryotic gene expression (2019)“…Cancer continues to remain a disease of scientific concern. Significant interest in targeting the Polo-Box-Domain (PBD) of Polo-like-kinase-1 (PLK-1) by novel…”
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Exploring the Binding Interaction of Active Compound of Pineapple against Foodborne Bacteria and Novel Coronavirus (SARS-CoV-2) Based on Molecular Docking and Simulation Studies
Published in Nutrients (25-07-2022)“…Natural resources, particularly plants and microbes, are an excellent source of bioactive molecules. Bromelain, a complex enzyme mixture found in pineapples,…”
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Methyltransferase as Antibiotics Against Foodborne Pathogens: An In Silico Approach for Exploring Enzyme as Enzymobiotics
Published in Frontiers in genetics (03-01-2022)“…The development of resistance in microbes against antibiotics and limited choice for the use of chemical preservatives in food lead the urgent need to search…”
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A novel polyherbal formulation containing thymoquinone attenuates carbon tetrachloride-induced hepatorenal injury in a rat model
Published in Asian Pacific journal of tropical biomedicine (01-04-2020)“…Objective: To evaluate a novel polyherbal formulation (BSVT) containing the standardized extracts from the leaves of Boerhavia diffusa, Solidago virgaurea,…”
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Embryonic NANOG Activity Defines Colorectal Cancer Stem Cells and Modulates through AP1- and TCF-dependent Mechanisms
Published in Stem cells (Dayton, Ohio) (01-10-2012)“…Embryonic NANOG (NANOG1) is considered as an important regulator of pluripotency while NANOGP8 (NANOG‐pseudogene) plays a role in tumorigenesis. Herein, we…”
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Nanophytosomal Gel of Heydotis corymbosa (L.) Extract against Psoriasis: Characterisation, In Vitro and In Vivo Biological Activity
Published in Pharmaceuticals (Basel, Switzerland) (06-02-2024)“…The current study was conducted to examine the possible advantages of (L.) Lam. extract nanogel as a perspective for enhanced permeation and extended skin…”
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FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation
Published in The Journal of experimental medicine (14-02-2011)“…The Fbxw7 (F-box/WD repeat-containing protein 7; also called CDC4, Sel10, Ago, and Fbw7) component of the SCF (Skp1/Cullin/F-box protein) E3 ubiquitin ligase…”
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A Study on Pharmacokinetic Functionalities and Safety Margins of an Optimized Simvastatin Nanoformulation
Published in Pharmaceuticals (Basel, Switzerland) (01-03-2023)“…A pharmaceutical formulation with favorable pharmacokinetic parameters is more likely to be efficacious and safe to overcome the failures of the drug resulting…”
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Ameliorative effect of camel's milk and Nigella Sativa Oil against thioacetamide-induced hepatorenal damage in rats
Published in Pharmacognosy Magazine (01-01-2018)“…Background: Camel milk (CM) and Nigella sativa (NS) have been traditionally claimed to cure wide range of diseases and used as medicine in different part of…”
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Identification of novel genetic variations affecting osteoarthritis patients
Published in BMC medical genetics (10-10-2016)“…Osteoarthritis (OA) is a progressive joint disease characterized by gradual degradation of extracellular matrix (ECM) components in the cartilage and bone. The…”
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Cardioprotective Effect of Coenzyme Q10 on Apoptotic Myocardial Cell Death by Regulation of Bcl-2 Gene Expression
Published in Journal of pharmacology & pharmacotherapeutics (01-07-2017)“…OBJECTIVESTo investigate the effect of coenzyme Q10 (CoQ10) on apoptotic myocardial cell death in rat model of heart ischemia and reperfusion I/R injury…”
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The molecular effects of Asperuloside against thermogenesis and anti-inflammatory process through multiple recent obesity pathways: An anti-obesity drug discovery by in-silico analysis
Published in Journal of King Saud University. Science (01-11-2023)“…Adenosine receptor signaling and suppressing potential pathways such as the aryl hydrocarbon receptor (AHR) and takeda G-protein-coupled receptor-5(TGR5) have…”
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HERisk and statistical clustering integrated for health risk modelling of PTEs in natural water resources for drinking and sanitary uses
Published in Toxin reviews (01-10-2024)Get full text
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Nanophytosomal Gel of IHeydotis corymbosa/I Extract against Psoriasis: Characterisation, In Vitro and In Vivo Biological Activity
Published in Pharmaceuticals (Basel, Switzerland) (01-02-2024)“…The current study was conducted to examine the possible advantages of Heydotis corymbosa (L.) Lam. extract nanogel as a perspective for enhanced permeation and…”
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In vivo models for assesment of wound healing potential: A systematic review
Published in Wound medicine (01-03-2018)Get full text
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