Search Results - "Abumrad, N N"

Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery by Albaugh, Vance L., Banan, Babak, Antoun, Joseph, Xiong, Yanhua, Guo, Yan, Ping, Jie, Alikhan, Muhammed, Clements, Blake Austin, Abumrad, Naji N., Flynn, Charles Robb

“…Bile diversion to the ileum (GB-IL) has strikingly similar metabolic and satiating effects to Roux-en-Y gastric bypass (RYGB) in rodent obesity models. The…”
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Endothelial cell CD36 regulates membrane ceramide formation, exosome fatty acid transfer and circulating fatty acid levels by Peche, V. S., Pietka, T. A., Jacome-Sosa, M., Samovski, D., Palacios, H., Chatterjee-Basu, G., Dudley, A. C., Beatty, W., Meyer, G. A., Goldberg, I. J., Abumrad, N. A.

“…Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs transfer FAs. FA interaction with apical membrane CD36 induces Src…”
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CD36 gene deletion reduces fat preference and intake but not post-oral fat conditioning in mice by Sclafani, A, Ackroff, K, Abumrad, N A

“…Several findings suggest the existence of a "fatty" taste, and the CD36 fatty acid translocase is a candidate taste receptor. The present study compared fat…”
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Hepatic TLR4 signaling in obese NAFLD by Sharifnia, Torfay, Antoun, Joseph, Verriere, Thomas G C, Suarez, Giovanni, Wattacheril, Julia, Wilson, Keith T, Peek, Jr, Richard M, Abumrad, Naji N, Flynn, Charles R

“…Nonalcoholic fatty liver disease occurs frequently in the setting of metabolic syndrome, but the factors leading to nonalcoholic steatohepatitis (NASH) are not…”
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Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery by Flynn, Charles Robb, Albaugh, Vance L., Cai, Steven, Cheung-Flynn, Joyce, Williams, Phillip E., Brucker, Robert M., Bordenstein, Seth R., Guo, Yan, Wasserman, David H., Abumrad, Naji N.

“…Roux-en-Y gastric bypass (RYGB) is highly effective in reversing obesity and associated diabetes. Recent observations in humans suggest a contributing role of…”
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HMG-1 as a Late Mediator of Endotoxin Lethality in Mice by Wang, Haichao, Bloom, Ona, Zhang, Minghuang, Vishnubhakat, Jaideep M., Ombrellino, Michael, Che, Jiantu, Frazier, Asia, Yang, Huan, Ivanova, Svetlana, Borovikova, Lyudmila, Manogue, Kirk R., Faist, Eugen, Abraham, Edward, Andersson, Jan, Andersson, Ulf, Molina, Patricia E., Abumrad, Naji N., Sama, Andrew, Tracey, Kevin J.

“…Endotoxin, a constituent of Gram-negative bacteria, stimulates macrophages to release large quantities of tumor necrosis factor (TNF) and interleukin-1 (IL-1),…”
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Importance of Caloric Restriction in the Early Improvements in Insulin Sensitivity After Roux-en-Y Gastric Bypass Surgery by Isbell, James M, Tamboli, Robyn A, Hansen, Erik N, Saliba, Jabbar, Dunn, Julia P, Phillips, Sharon E, Marks-Shulman, Pamela A, Abumrad, Naji N

“…OBJECTIVE: Many of the metabolic benefits of Roux-en-Y gastric bypass (RYGB) occur before weight loss. In this study we investigated the influence of caloric…”
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The cellular, metabolic, and systemic consequences of aggressive fluid resuscitation strategies by COTTON, Bryan A, GUY, Jeffrey S, MORRIS, John A, ABUMRAD, Naji N

“…Increasing evidence has demonstrated that aggressive crystalloid-based resuscitation strategies are associated with cardiac and pulmonary complications,…”
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Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward by Reddy, India A, Smith, Nicholas K, Erreger, Kevin, Ghose, Dipanwita, Saunders, Christine, Foster, Daniel J, Turner, Brandon, Poe, Amanda, Albaugh, Vance L, McGuinness, Owen, Hackett, Troy A, Grueter, Brad A, Abumrad, Naji N, Flynn, Charles Robb, Galli, Aurelio

“…The gut-to-brain axis exhibits significant control over motivated behavior. However, mechanisms supporting this communication are poorly understood. We reveal…”
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Omega-3 fatty acids inhibit the up-regulation of endothelial chemokines in maintenance hemodialysis patients by Hung, Adriana M, Booker, Cindy, Ellis, Charles D, Siew, Edward D, Graves, Amy J, Shintani, Ayumi, Abumrad, Naji N, Himmelfarb, Jonathan, Ikizler, Talat Alp

“…Chronic systemic inflammation is common in patients with chronic kidney disease on dialysis (CKD5D) and has been considered a key mediator of the increased…”
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Metabolic Effects of Bile Acids: Potential Role in Bariatric Surgery by Flynn, Charles R, Albaugh, Vance L, Abumrad, Naji N

“…Bariatric surgery is the most effective and durable treatment for morbid obesity, with an unexplained yet beneficial side effect of restoring insulin…”
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Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice by Herrick, Mary K, Favela, Kristin M, Simerly, Richard B, Abumrad, Naji N, Bingham, Nathan C

“…Exposure of rodents to chronic high-fat diet (HFD) results in upregulation of inflammatory markers and proliferation of microglia within the mediobasal…”
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Surgical treatment of obesity [version 1; peer review: 4 approved] by Albaugh, Vance L, Abumrad, Naji N

“…Obesity prevalence continues to increase worldwide, as do the numerous chronic diseases associated with obesity, including diabetes, non-alcoholic fatty liver…”
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A randomized controlled pilot trial of anakinra and pioglitazone for protein metabolism in patients on maintenance haemodialysis by Ertuglu, Lale A., Deger, Serpil Muge, Alsouqi, Aseel, Hung, Adriana, Gamboa, Jorge, Mambungu, Cindy, Sha, Feng, Siew, Edward, Abumrad, Naji N., Ikizler, T. Alp

“…Background Chronic inflammation and insulin resistance are highly prevalent in patients on maintenance haemodialysis (MHD) and are strongly associated with…”
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Subchronic (90-day) repeated dose toxicity study of 2-hydroxybenzylamine acetate in rats by Fuller, John C., Pitchford, Lisa M., Abumrad, Naji N., Rathmacher, John A.

“…2-Hydroxybenzylamine (2-HOBA), a naturally occurring compound found in buckwheat, can protect cells and tissues from oxidative stress. In this study, 2-HOBA…”
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Relationship between subjective effects of cocaine and dopamine transporter occupancy by Volkow, N. D, Wang, G.-J, Fischman, M. W, Foltin, R. W, Fowler, J. S, Abumrad, N. N, Vitkun, S, Logan, J, Gatley, S. J, Pappas, N, Hitzemann, R, Shea, C. E

“…Cocaine is believed to work by blocking the dopamine transporter (DAT) and thereby increasing the availability of free dopamine within the brain. Although this…”
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Brief communication: β-cell function influences dopamine receptor availability by Dunn, Julia P, Abumrad, Naji N, Patterson, Bruce W, Kessler, Robert M, Tamboli, Robyn A

“…We aim to identify physiologic regulators of dopamine (DA) signaling in obesity but previously did not find a compelling relationship with insulin sensitivity…”
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A post-developmental genetic screen for zebrafish models of inherited liver disease by Kim, Seok-Hyung, Wu, Shu-Yu, Baek, Jeong-In, Choi, Soo Young, Su, Yanhui, Flynn, Charles R, Gamse, Joshua T, Ess, Kevin C, Hardiman, Gary, Lipschutz, Joshua H, Abumrad, Naji N, Rockey, Don C

“…Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease such as simple steatosis, nonalcoholic steatohepatitis…”
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Risk factors for pressure ulcers in acute care hospitals by Fogerty, Mary D., Abumrad, Naji N., Nanney, Lillian, Arbogast, Patrick G., Poulose, Benjamin, Barbul, Adrian

“…ABSTRACT Selection of patients for preventive measures to protect against pressure ulcers relies on clinical scales and provider judgment, which vary widely…”
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Defective Uptake and Utilization of Long Chain Fatty Acids in Muscle and Adipose Tissues of CD36 Knockout Mice by Coburn, Chris T., Knapp, F.F., Febbraio, Maria, Beets, Arnold L., Silverstein, Roy L., Abumrad, Nada A.

“…The transmembrane protein CD36 has been identified in isolated cell studies as a putative transporter of long chain fatty acids. In humans, an association…”
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