Search Results - "Abumiya, Takeo"

Mapping altered brain connectivity and its clinical associations in adult moyamoya disease: A resting-state functional MRI study by Kazumata, Ken, Tha, Khin Khin, Uchino, Haruto, Ito, Masaki, Nakayama, Naoki, Abumiya, Takeo

“…Detection of subtle ischemic injuries in moyamoya disease may enable optimization of timing of revascularization surgery, and could potentially improve…”
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Cellular Functions and Gene and Protein Expression Profiles in Endothelial Cells Derived from Moyamoya Disease-Specific iPS Cells by Hamauchi, Shuji, Shichinohe, Hideo, Uchino, Haruto, Yamaguchi, Shigeru, Nakayama, Naoki, Kazumata, Ken, Osanai, Toshiya, Abumiya, Takeo, Houkin, Kiyohiro, Era, Takumi

“…Moyamoya disease (MMD) is a slow, progressive steno-occlusive disease, arising in the terminal portions of the cerebral internal carotid artery. However, the…”
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Transarterial Regional Brain Hypothermia Inhibits Acute Aquaporin-4 Surge and Sequential Microvascular Events in Ischemia/Reperfusion Injury by Kurisu, Kota, Abumiya, Takeo, Nakamura, Hideki, Shimbo, Daisuke, Shichinohe, Hideo, Nakayama, Naoki, Kazumata, Ken, Shimizu, Hiroshi, Houkin, Kiyohiro

“…Abstract BACKGROUND Although transarterial regional hypothermia is an attractive alternative to general hypothermia, its efficacy and underlying mechanisms…”
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Association of CYP2C19 Polymorphisms With Clopidogrel Reactivity and Clinical Outcomes in Chronic Ischemic Stroke by Tanaka, Tomotaka, Yamagami, Hiroshi, Ihara, Masafumi, Miyata, Toshiyuki, Miyata, Shigeki, Hamasaki, Toshimitsu, Amano, Shu, Fukuma, Kazuki, Yamamoto, Haruko, Nakagawara, Jyoji, Furui, Eisuke, Uchiyama, Shinichiro, Hyun, Boohan, Yamamoto, Yasumasa, Manabe, Yasuhiro, Ito, Yasuhiro, Fukunaga, Ryuzo, Abumiya, Takeo, Yasaka, Masahiro, Kitagawa, Kazuo, Toyoda, Kazunori, Nagatsuka, Kazuyuki

“…Background:CYP2C19variants are associated with the antiplatelet effects of clopidogrel against recurrent cardiovascular events. However, it remains unknown…”
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Research on advanced intervention using novel bone marrOW stem cell (RAINBOW): a study protocol for a phase I, open-label, uncontrolled, dose-response trial of autologous bone marrow stromal cell transplantation in patients with acute ischemic stroke by Shichinohe, Hideo, Kawabori, Masahito, Iijima, Hiroaki, Teramoto, Tuyoshi, Abumiya, Takeo, Nakayama, Naoki, Kazumata, Ken, Terasaka, Shunsuke, Arato, Teruyo, Houkin, Kiyohiro

“…Stroke is a leading cause of death and disability, and despite intensive research, few treatment options exist. However, a recent breakthrough in cell therapy…”
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Topographic changes in cerebral blood flow and reduced white matter integrity in the first 2 weeks following revascularization surgery in adult moyamoya disease by Kazumata, Ken, Tha, Khin Khin, Uchino, Haruto, Shiga, Tohru, Shichinohe, Hideo, Ito, Masaki, Nakayama, Naoki, Abumiya, Takeo

“…OBJECTIVE After revascularization surgery, hyperperfusion and ischemia are associated with morbidity and mortality in adult moyamoya disease (MMD). However,…”
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Post-ischemic intra-arterial infusion of liposome-encapsulated hemoglobin can reduce ischemia reperfusion injury by Shimbo, Daisuke, Abumiya, Takeo, Shichinohe, Hideo, Nakayama, Naoki, Kazumata, Ken, Houkin, Kiyohiro

“…Abstract Despite successful revascularization, reperfusion after prolonged ischemia causes ischemia reperfusion (I/R) injury. Recruitment and activation of…”
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Neuroprotective effects of cilostazol are mediated by multiple mechanisms in a mouse model of permanent focal ischemia by Shichinohe, Hideo, Tan, Chengbo, Abumiya, Takeo, Nakayama, Naoki, Kazumata, Ken, Hokari, Masaaki, Houkin, Kiyohiro, Kuroda, Satoshi

“…Abstract The phosphodiesterase (PDE) 3 inhibitor cilostazol, used as an anti-platelet drug, reportedly can also ameliorate ischemic brain injury. Here, we…”
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Ultrasound-guided Femoral Artery Access for Minimally Invasive Neuro-intervention and Risk Factors for Access Site Hematoma by KURISU, Kota, OSANAI, Toshiya, KAZUMATA, Ken, NAKAYAMA, Naoki, ABUMIYA, Takeo, SHICHINOHE, Hideo, SHIMODA, Yusuke, HOUKIN, Kiyohiro

“…Although ultrasound (US) guidance for venous access is becoming the “standard of care” for preventing access site complications, its feasibility for arterial…”
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Increased Blood Viscosity in Ischemic Stroke Patients with Small Artery Occlusion Measured by an Electromagnetic Spinning Sphere Viscometer by Furukawa, Koji, MD, Abumiya, Takeo, MD, PhD, Sakai, Keiji, PhD, Hirano, Miki, MS, Osanai, Toshiya, MD, PhD, Shichinohe, Hideo, MD, PhD, Nakayama, Naoki, MD, PhD, Kazumata, Ken, MD, PhD, Hida, Kazutoshi, MD, PhD, Houkin, Kiyohiro, MD, PhD

“…Background and Purpose High blood viscosity causes blood stagnation and subsequent pathological thrombotic events, resulting in the development of ischemic…”
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Short-, middle- and long-term safety of superparamagnetic iron oxide-labeled allogeneic bone marrow stromal cell transplantation in rat model of lacunar infarction by Tan, Chengbo, Shichinohe, Hideo, Abumiya, Takeo, Nakayama, Naoki, Kazumata, Ken, Hokari, Masaaki, Hamauchi, Shuji, Houkin, Kiyohiro

“…Recently, both basic and clinical studies demonstrated that bone marrow stromal cell (BMSC) transplantation therapy can promote functional recovery of patients…”
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Superior Microvascular Perfusion of Infused Liposome-Encapsulated Hemoglobin Prior to Reductions in Infarctions after Transient Focal Cerebral Ischemia by Shimbo, Daisuke, Abumiya, Takeo, Kurisu, Kota, Osanai, Toshiya, Shichinohe, Hideo, Nakayama, Naoki, Kazumata, Ken, Nakamura, Hideki, Shimuzu, Hiroshi, Houkin, Kiyohiro

“…The development of cerebral infarction after transient ischemia is attributed to postischemic delayed hypoperfusion in the microvascular region. In the present…”
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Measurement of human blood viscosity by an electromagnetic spinning sphere viscometer by Furukawa, Koji, Abumiya, Takeo, Sakai, Keiji, Hirano, Miki, Osanai, Toshiya, Shichinohe, Hideo, Nakayama, Naoki, Kazumata, Ken, Aida, Toshimitsu, Houkin, Kiyohiro

“…We herein applied an electromagnetic spinning sphere (EMS) viscometer to the measurement of human blood viscosity for the first time. We collected blood…”
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Cardiovascular events occur independently of high on-aspirin platelet reactivity and residual COX-1 activity in stable cardiovascular patients by Nagatsuka, Kazuyuki, Miyata, Shigeki, Kada, Akiko, Kawamura, Atsushi, Nakagawara, Jyoji, Furui, Eisuke, Takiuchi, Shin, Taomoto, Katsushi, Kario, Kazuomi, Uchiyama, Shinichiro, Saito, Kozue, Nagao, Takehiko, Kitagawa, Kazuo, Hosomi, Naohisa, Tanaka, Keiji, Kaikita, Koichi, Katayama, Yasuo, Abumiya, Takeo, Nakane, Hiroshi, Wada, Hideo, Hattori, Akira, Kimura, Kazumi, Isshiki, Takaaki, Nishikawa, Masakatsu, Yamawaki, Takemori, Yonemoto, Naohiro, Okada, Hiromi, Ogawa, Hisao, Minematsu, Kazuo, Miyata, Toshiyuki

“…Several studies have indicated that approximately 25 % of patients treated with aspirin exhibit high on-treatment platelet reactivity (HTPR), which is…”
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[18F]DPA-714 PET imaging shows immunomodulatory effect of intravenous administration of bone marrow stromal cells after transient focal ischemia by Tan, Chengbo, Zhao, Songji, Higashikawa, Kei, Wang, Zifeng, Kawabori, Masahito, Abumiya, Takeo, Nakayama, Naoki, Kazumata, Ken, Ukon, Naoyuki, Yasui, Hironobu, Tamaki, Nagara, Kuge, Yuji, Shichinohe, Hideo, Houkin, Kiyohiro

“…Background The potential application of bone marrow stromal cell (BMSC) therapy in stroke has been anticipated due to its immunomodulatory effects. Recently,…”
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Surgical Outcome of Cerebral Aneurysm Clipping Treated with Immunosuppressants: Report of 11 Cases and Review of the Literature by HOKARI, Masaaki, NAKAYAMA, Naoki, KAZUMATA, Ken, OSANAI, Toshiya, SHICHINOHE, Hideo, ABUMIYA, Takeo, HOUKIN, Kiyohiro

“…There are no reports on the outcomes of clippings in patients who receive immunosuppressants, for example, due to connective tissue diseases or following organ…”
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Matrix Metalloproteinases Increase Very Early During Experimental Focal Cerebral Ischemia by Heo, Ji Hoe, Lucero, Jacinta, Abumiya, Takeo, Koziol, James A., Copeland, Brian R., del Zoppo, Gregory J.

“…Microvascular integrity is lost during focal cerebral ischemia. The degradation of the basal lamina and extracellular matrix are, in part, responsible for the…”
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Advanced Glycation End Products Increase Permeability of Brain Microvascular Endothelial Cells through Reactive Oxygen Species–Induced Vascular Endothelial Growth Factor Expression by Niiya, Yoshimasa, MD, PhD, Abumiya, Takeo, MD, PhD, Yamagishi, Sho-ichi, MD, PhD, Takino, Jun-ichi, MS, Takeuchi, Masayoshi, PhD

“…Background Advanced glycation end products (AGEs) have been implicated as important factors in the pathogenesis of diabetic vascular complication. The aim of…”
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Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke by Shichinohe, Hideo, Wang, Zifeng, Hamauchi, Shuji, Abumiya, Takeo, Nakayama, Naoki, Kazumata, Ken, Tan, Chengbo, Kudo, Kohsuke, Takamoto, Shigeru, Houkin, Kiyohiro, Ito, Tsuneo

“…Currently, there is increasing interest in human bone marrow stromal cells (hBMSCs) as regeneration therapy against cerebral stroke. The aim of the present…”
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Moyamoya Vasculopathy and Moyamoya-Related Systemic Vasculopathy: A Review With Histopathological and Genetic Viewpoints by Abumiya, Takeo, Fujimura, Miki

“…Systemic vasculopathy has occasionally been reported in cases of moyamoya disease (MMD). Since the pathological relationship between moyamoya vasculopathy…”
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