Search Results - "Abujarour, R"

Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies by Hammer, Quirin, Perica, Karlo, Mbofung, Rina M, van Ooijen, Hanna, Martin, Karen E, Momayyezi, Pouria, Varady, Erika, Pan, Yijia, Jelcic, Mark, Groff, Brian, Abujarour, Ramzey, Krokeide, Silje Z, Lee, Tom, Williams, Alan, Goodridge, Jode P, Valamehr, Bahram, Önfelt, Björn, Sadelain, Michel, Malmberg, Karl-Johan

“…Allogeneic cellular immunotherapies hold promise for broad clinical implementation but face limitations due to potential rejection of donor cells by the host…”
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Combined Genetic Ablation of CD54 and CD58 in CAR Engineered Cytotoxic Lymphocytes Effectively Averts Allogeneic Immune Cell Rejection by Hammer, Quirin, Perica, Karlo, Mbofung, Rina M, van Ooijen, Hanna, Varady, Erika, Jelcic, Mark, Pan, Yijia, Momayyezi, Pouria, Groff, Brian, Abujarour, Ramzey, Krokeide, Silje Zandstra, Lee, Tom, Williams, Alan M, Goodridge, Jode P, Valamehr, Bahram, Onfelt, Bjorn, Sadelain, Michel, Malmberg, Karl-Johan

“…Allogeneic cell therapies hold promise to be cost effective with scaled manufacturing for multi-dosing and on-demand off-the-shelf availability. A critical…”
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A Novel Stealth Strategy That Activates Adoptively Transferred Allogeneic Immune Cells and Avoids Rejection for Off-the-Shelf Cell-Based Cancer Therapy by Williams, Alan M, Hayama, Ken, Pan, Yijia, Groff, Brian, Mbofung, Rina M, Fong, Lauren, Brookhouser, Nicholas, Mandefro, Berhan, Abujarour, Ramzey, Lee, Tom, Hammer, Quirin, Malmberg, Karl-Johan, Mamonkin, Maksim, Bjordahl, Ryan, Goodridge, Jode P, Valamehr, Bahram

“…Chimeric antigen receptor (CAR) T-cell therapies have revolutionized the treatment of hematologic malignancies, however, logistical complexities associated…”
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FT538: Preclinical Development of an Off-the-Shelf Adoptive NK Cell Immunotherapy with Targeted Disruption of CD38 to Prevent Anti-CD38 Antibody-Mediated Fratricide and Enhance ADCC in Multiple Myeloma When Combined with Daratumumab by Bjordahl, Ryan, Gaidarova, Svetlana, Woan, Karrune, Cichocki, Frank, Bonello, Greg, Robinson, Megan, Ruller, Chelsea, Pribadi, Mochtar, Dinella, Jason, Fong, Lauren, Huffman, Janel, Chu, Hui-yi, Lee, Tom, Abujarour, Ramzey, Kaufman, Dan S, Malmberg, Karl-Johan, Miller, Jeffrey S., Valamehr, Bahram

“…Monoclonal antibody (mAb) treatment is an effective therapeutic strategy for many cancer types, though there remains meaningful opportunity to improve mAb…”
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A novel synthetic stealth receptor that redirects host immune cell alloreactivity and potentiates functional persistence of adoptively transferred off-the-shelf cell-based cancer therapy by Williams, AM, Hayama, K, Pan, YJ, Groff, B, Mbofung, R, Fong, L, Brookhouser, N, Mandefro, B, Abujarour, R, Lee, T, Hammer, Q, Malmberg, KJ, Mamonkin, M, Bjordahl, R, Goodridge, J, Valamehr, B

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Evidence that the transport of ricin to the cytoplasm is independent of both Rab6A and COPI by Chen, Alice, AbuJarour, Ramzey J, Draper, Rockford K

“…Cholera toxin, Shiga toxin and ricin are examples of protein toxins that require retrograde transport from the Golgi complex into the endoplasmic reticulum…”
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p97 Is in a Complex with Cholera Toxin and Influences the Transport of Cholera Toxin and Related Toxins to the Cytoplasm by AbuJarour, Ramzey J., Dalal, Seema, Hanson, Phyllis I., Draper, Rockford K.

“…Certain protein toxins, including cholera toxin, ricin, and Pseudomonas aeruginosa exotoxin A, are transported to the lumen of the endoplasmic reticulum where…”
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