Search Results - "Abuhamad, Asmaa Y"
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Understanding Glioblastoma Biomarkers: Knocking a Mountain with a Hammer
Published in Cells (Basel, Switzerland) (16-05-2020)“…Gliomas are the most frequent and deadly form of human primary brain tumors. Among them, the most common and aggressive type is the high-grade glioblastoma…”
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Application of 3D-Printed Bioinks in Chronic Wound Healing: A Scoping Review
Published in Polymers (29-08-2024)“…Chronic wounds, such as diabetic foot ulcers, pressure ulcers, and venous ulcers, pose significant clinical challenges and burden healthcare systems worldwide…”
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Cancer Cell-Derived PDGFB Stimulates mTORC1 Activation in Renal Carcinoma
Published in International journal of molecular sciences (29-03-2023)“…Clear cell renal cell carcinoma (ccRCC) is a hypervascular tumor that is characterized by bi-allelic inactivation of the tumor suppressor gene and mTOR…”
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Reverting TP53 Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations
Published in Cells (Basel, Switzerland) (11-05-2022)“…Breast cancer is the leading cause of cancer-related deaths in women. The aggressive breast cancer subtype is commonly linked to the genetic alterations in the…”
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dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer
Published in CRISPR journal (01-04-2024)“…Clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing is evolving into an essential tool in the field of biological and…”
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Novel imidazo[1,2-a]pyridine inhibits AKT/mTOR pathway and induces cell cycle arrest and apoptosis in melanoma and cervical cancer cells
Published in Oncology letters (01-07-2019)“…The present study aimed to investigate the anti-cancer activity of imidazo[1,2-a]pyridine 5-7 in the A375 and WM115 melanoma and HeLa cervical cancer cell…”
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CRISPR-Mediated Generation of In Vitro Breast Cancer Models to Study P53 Gain of Function Mutation
Published in Asia-Pacific journal of molecular biology and biotechnology (01-06-2021)“…Introduction: Breast cancer (BC) is the second leading cause of cancer-related deaths among women. Aggressive BC is commonly linked to P53 gene mutations. The…”
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