Search Results - "Abuelezz, Sally A."

PCSK9 Inhibition Reduces Depressive like Behavior in CUMS-Exposed Rats: Highlights on HMGB1/RAGE/TLR4 Pathway, NLRP3 Inflammasome Complex and IDO-1 by Hendawy, Nevien, Salaheldin, Tala H., Abuelezz, Sally A.

“…Ample evidence has pointed to a close link between cardiovascular diseases (CVD) and depression. Inflammatory pathways including the high-mobility-group-box-1…”
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HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis by Abuelezz, Sally A., Hendawy, Nevien

“…Alzheimer's disease (AD) is a leading health problem in which increased amyloid β (Aβ) accumulation may occur due to abnormal Aβ precursor protein processing…”
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Spotlight on Coenzyme Q10 in scopolamine-induced Alzheimer's disease: oxidative stress/PI3K/AKT/GSK 3ß/CREB/BDNF/TrKB by Abuelezz, Sally A, Hendawy, Nevien

“…Excess amyloid beta (Aβ) and oxidative stress (OS) are inextricable hallmarks of the neuronal damage associated Alzheimer's disease. Aβ-induced cognitive and…”
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The potential benefit of combined versus monotherapy of coenzyme Q10 and fluoxetine on depressive-like behaviors and intermediates coupled to Gsk-3β in rats by Abuelezz, Sally A., Hendawy, Nevien, Magdy, Yosra

“…As a part of the serotoninergic dysfunction implicated in neurobiology of depression, evidence has focused on serotonin (5-HT) receptors downstream signaling…”
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Insights into the potential antidepressant mechanisms of cilostazol in chronically restraint rats: impact on the Nrf2 pathway by Abuelezz, Sally A, Hendawy, Nevien

“…Ample evidence has pointed to a close link between oxidative stress, mitochondrial dysfunction, and depression. Nuclear factor-erythroid 2-related factor-2…”
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Targeting Oxidative Stress, Cytokines and Serotonin Interactions Via Indoleamine 2, 3 Dioxygenase by Coenzyme Q10: Role in Suppressing Depressive Like Behavior in Rats by Abuelezz, Sally A., Hendawy, Nevien, Magdy, Yosra

“…Depression is a major health problem in which oxidative stress and inflammation are inextricably connected in its pathophysiology. Coenzyme Q10 (CoQ10) is an…”
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Sonic hedgehog pathway as a new target of atypical antipsychotics: Revisiting of amisulpride and aripiprazole effects in a rat model of schizophrenia by Abdelfattah, Ahmed M., Abuelezz, Sally A., Hendawy, Nevien, Negm, Eman A., Nawishy, Salwa Abd El Khalek, Khalil, Ahmed Mohamed Mohamed

“…Schizophrenia is a chronic mental illness presented by cognitive deficits that precede its positive and negative symptoms. Sonic hedgehog (Shh)-pathway…”
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Validation of prenatal versus postnatal valproic acid rat models of autism: A behavioral and neurobiological study by Elnahas, Esraa M., Abuelezz, Sally A., Mohamad, Magda I., Nabil, Mai M., Abdelraouf, Sahar M., Bahaa, Nevine, Hassan, Ghada AM, Ibrahim, Eman A., Ahmed, Asmaa I., Aboul-Fotouh, Sawsan

“…Despite the increasing prevalence of autism spectrum disorder (ASD), there is still a deficiency in understanding its exact pathophysiology and treatment,…”
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Alleviation of renal mitochondrial dysfunction and apoptosis underlies the protective effect of sitagliptin in gentamicin-induced nephrotoxicity by Abuelezz, Sally A., Hendawy, Nevien, Abdel Gawad, Sara

“…Objective This study aimed to investigate the potential protective effect of sitagliptin on gentamicin‐induced nephrotoxicity and to elucidate the underlying…”
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Novel role of peroxisome proliferator activated receptor-α in valproic acid rat model of autism: Mechanistic study of risperidone and metformin monotherapy versus combination by Elnahas, Esraa M., Abuelezz, Sally A., Mohamad, Magda I., Nabil, Mai M., Abdelraouf, Sahar M., Bahaa, Nevine, Hassan, Ghada A.M., Aboul-Fotouh, Sawsan

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder of heterogenous etiology exhibiting a challenge in understanding its exact…”
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Aliskiren attenuates bleomycin-induced pulmonary fibrosis in rats: focus on oxidative stress, advanced glycation end products, and matrix metalloproteinase-9 by Abuelezz, Sally A., Hendawy, Nevien, Osman, Wesam M.

“…Pulmonary fibrosis is a progressive lung disorder with high mortality rate and limited successful treatment. This study was designed to assess the potential…”
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The anti-osteoporotic and anti-atherogenic effects of alendronate and simvastatin in ovariectomized rats fed high fat diet: A comparative study of combination therapy versus monotherapy by Mohamed, Maha Tarek, Abuelezz, Sally A, Atalla, Suzi Sobhy, El Aziz, Lobna Fouad Abd, Gorge, Sonia Salib

“…Abstract Aim Epidemiological studies suggest a possible link between osteoporosis and cardiovascular diseases. Mevalonate pathway was pointed to as a part of…”
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